Gene: L1cam (L1 cell adhesion molecule) Rattus norvegicus
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Symbol: L1cam
Name: L1 cell adhesion molecule
Description: ENCODES a protein that exhibits PDZ domain binding; identical protein binding (ortholog); integrin binding (ortholog); INVOLVED IN axonal fasciculation; cellular response to dexamethasone stimulus; cellular response to ethanol; ASSOCIATED WITH anxiety disorder; hypothyroidism; mental depression; FOUND IN axon; axonal growth cone; cell surface; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil
AGR Description: Exhibits PDZ domain binding activity; involved in several processes, including cellular response to growth factor stimulus, cellular response to hormone stimulus, and generation of neurons; localizes to several cellular components, including the Schaffer collateral - CA1 synapse, cell surface, and neuron projection; biomarker of anxiety disorder, hypothyroidism, and mental depression; orthologous to human L1CAM (L1 cell adhesion molecule).
Merged Description: Exhibits PDZ domain binding activity; involved in several processes, including cellular response to growth factor stimulus, cellular response to hormone stimulus, and generation of neurons; localizes to several cellular components, including the Schaffer collateral - CA1 synapse, cell surface, and neuron projection; biomarker of anxiety disorder, hypothyroidism, and mental depression; orthologous to human L1CAM (L1 cell adhesion molecule); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Hsas; Hyd; L1; L1 cell adhesion molecule (mapped); L1cam_mapped; N-CAM L1; N-CAM-L1; NCAM-L1; NCAML1; nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; neuron-glia cell adhesion molecule; NgCAM; NILE
Orthologs:
Homo sapiens (human) : L1CAM (L1 cell adhesion molecule)  HGNC  Alliance
Mus musculus (house mouse) : L1cam (L1 cell adhesion molecule)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : L1cam (L1 cell adhesion molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : L1CAM (L1 cell adhesion molecule)
Canis lupus familiaris (dog) : L1CAM (L1 cell adhesion molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : L1cam (L1 cell adhesion molecule)
Sus scrofa (pig) : L1CAM (L1 cell adhesion molecule)
more info ...
Allele / Splice: L1cam_v1   L1cam_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X156,901,244 - 156,928,064 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,649,353 - 152,676,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,784,792 - 159,801,553 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1136,279,868 - 136,293,057 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Gene Ontology Annotations
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References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on L1cam
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619777
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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