Slc27a5 (solute carrier family 27 member 5) - Rat Genome Database

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Gene: Slc27a5 (solute carrier family 27 member 5) Rattus norvegicus
Analyze
Symbol: Slc27a5
Name: solute carrier family 27 member 5
RGD ID: 708535
Description: Enables cholate-CoA ligase activity. Involved in bile acid metabolic process. Located in intracellular membrane-bounded organelle. Part of protein-containing complex. Orthologous to human SLC27A5 (solute carrier family 27 member 5); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BA-CoA ligase; BACS; BAL; bile acid CoA ligase; bile acid-CoA ligase; bile acyl-CoA synthetase; cholate--CoA ligase; FATP-5; fatty acid transport protein 5; LOC79111; long-chain fatty acid transport protein 5; long-chain-fatty-acid--CoA ligase; rBAL-1; solute carrier family 27 (fatty acid transporter), member 5; very long-chain acyl-CoA synthetase-related protein; VLACS-related; VLACSR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Slc27a5m1Mcwi   Slc27a5m2Mcwi  
Genetic Models: FHH-Slc27a5m1Mcwi BN-Slc27a5m2Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2173,616,556 - 73,627,149 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl173,616,564 - 73,627,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,996,966 - 79,007,611 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0187,561,304 - 87,571,949 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0180,752,046 - 80,762,691 (-)NCBIRnor_WKY
Rnor_6.0165,576,599 - 65,587,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl165,576,535 - 65,587,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,387,832 - 66,398,425 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4172,924,630 - 72,935,223 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1173,002,740 - 73,013,332 (+)NCBI
Celera160,212,177 - 60,222,770 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
berberine  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
cholic acid  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
deoxycholic acid  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
glafenine  (EXP)
glycidol  (EXP)
GW 4064  (ISO)
imipenem hydrate  (ISO)
L-methionine  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (ISO)
LY294002  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nimesulide  (EXP)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
olanzapine  (ISO)
oxycodone  (EXP)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rifampicin  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
streptozocin  (ISO)
T-2 toxin  (EXP)
tert-butyl ethyl ether  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thioacetamide  (EXP)
triphenyl phosphate  (EXP)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

References

References - curated
# Reference Title Reference Citation
1. Molecular cloning and expression of rat liver bile acid CoA ligase. Falany CN, etal., J Lipid Res 2002 Dec;43(12):2062-71.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat liver bile acid CoA:amino acid N-acyltransferase: expression, characterization, and peroxisomal localization. He D, etal., J Lipid Res. 2003 Dec;44(12):2242-9. Epub 2003 Sep 1.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Purification and characterization of a rat liver bile acid coenzyme A ligase from rat liver microsomes. Wheeler JB, etal., Arch Biochem Biophys. 1997 Dec 1;348(1):15-24.
Additional References at PubMed
PMID:9671728   PMID:10479480   PMID:10749848   PMID:11980911   PMID:12477932   PMID:15489334   PMID:16618416   PMID:16618417   PMID:20530735  


Genomics

Comparative Map Data
Slc27a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2173,616,556 - 73,627,149 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl173,616,564 - 73,627,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,996,966 - 79,007,611 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0187,561,304 - 87,571,949 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0180,752,046 - 80,762,691 (-)NCBIRnor_WKY
Rnor_6.0165,576,599 - 65,587,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl165,576,535 - 65,587,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,387,832 - 66,398,425 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4172,924,630 - 72,935,223 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1173,002,740 - 73,013,332 (+)NCBI
Celera160,212,177 - 60,222,770 (+)NCBICelera
Cytogenetic Map1q12NCBI
SLC27A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381958,498,333 - 58,511,992 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1958,479,512 - 58,512,413 (-)EnsemblGRCh38hg38GRCh38
GRCh371959,009,700 - 59,023,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361963,701,517 - 63,715,161 (-)NCBINCBI36Build 36hg18NCBI36
Build 341963,701,517 - 63,715,157NCBI
Celera1956,053,816 - 56,067,542 (-)NCBICelera
Cytogenetic Map19q13.43NCBI
HuRef1955,319,377 - 55,333,864 (-)NCBIHuRef
CHM1_11959,003,732 - 59,017,394 (-)NCBICHM1_1
T2T-CHM13v2.01961,594,402 - 61,607,985 (-)NCBIT2T-CHM13v2.0
Slc27a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39712,722,273 - 12,732,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl712,722,273 - 12,732,119 (-)EnsemblGRCm39 Ensembl
GRCm38712,988,346 - 12,998,192 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl712,988,346 - 12,998,192 (-)EnsemblGRCm38mm10GRCm38
MGSCv37713,573,695 - 13,583,541 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36711,888,532 - 11,898,329 (-)NCBIMGSCv36mm8
Celera710,613,981 - 10,626,137 (-)NCBICelera
Cytogenetic Map7A1NCBI
Slc27a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555841,112,117 - 1,121,323 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555841,112,387 - 1,121,500 (-)NCBIChiLan1.0ChiLan1.0
SLC27A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11964,329,567 - 64,342,630 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1964,329,567 - 64,342,630 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01955,507,455 - 55,520,448 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC27A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1199,435,140 - 99,438,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,833,542 - 99,842,039 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01100,048,410 - 100,056,905 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1100,041,887 - 100,056,901 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1199,693,751 - 99,702,249 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0199,406,581 - 99,415,077 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01100,161,220 - 100,169,717 (+)NCBIUU_Cfam_GSD_1.0
Slc27a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118218,019,774 - 218,029,145 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493706290,217 - 98,562 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC27A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,065,830 - 63,075,202 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,068,880 - 63,075,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC27A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1650,782,713 - 50,793,816 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl650,781,544 - 50,792,515 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660454,088,423 - 4,092,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc27a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483284,552 - 92,556 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462483284,456 - 92,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc27a5
69 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:24
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000026575
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat

Markers in Region
BE107935  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2173,616,603 - 73,616,779 (-)MAPPERmRatBN7.2
Rnor_6.0165,586,969 - 65,587,144NCBIRnor6.0
Rnor_5.0166,398,202 - 66,398,377UniSTSRnor5.0
RGSC_v3.4172,935,000 - 72,935,175UniSTSRGSC3.4
Celera160,222,547 - 60,222,722UniSTS
RH 3.4 Map1765.69UniSTS
Cytogenetic Map1q21UniSTS


Genetic Models
This gene Slc27a5 is modified in the following models/strains

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 31 31 31 4
Low 2 19 10 5 10 3 3 38 17 14 7 3
Below cutoff 1 11 7 14 5 8 22 16 19 4 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000026575   ⟹   ENSRNOP00000026574
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl173,616,564 - 73,627,172 (-)Ensembl
Rnor_6.0 Ensembl165,576,535 - 65,587,186 (+)Ensembl
RefSeq Acc Id: NM_024143   ⟹   NP_077057
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2173,616,556 - 73,627,149 (-)NCBI
Rnor_6.0165,576,599 - 65,587,192 (+)NCBI
Rnor_5.0166,387,832 - 66,398,425 (+)NCBI
RGSC_v3.4172,924,630 - 72,935,223 (+)RGD
Celera160,212,177 - 60,222,770 (+)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_077057   ⟸   NM_024143
- Peptide Label: precursor
- UniProtKB: Q9ES38 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000026574   ⟸   ENSRNOT00000026575

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ES38-F1-model_v2 AlphaFold Q9ES38 1-690 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689674
Promoter ID:EPDNEW_R199
Type:initiation region
Name:Slc27a5_1
Description:solute carrier family 27 member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0165,576,595 - 65,576,655EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708535 AgrOrtholog
BioCyc Gene G2FUF-60701 BioCyc
BioCyc Pathway PWY-6061 [bile acid biosynthesis, neutral pathway] BioCyc
Ensembl Genes ENSRNOG00000019626 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000026574 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026575 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.300.30 UniProtKB/Swiss-Prot
  3.40.50.12780 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7370589 IMAGE-MGC_LOAD
InterPro AMP-bd_C UniProtKB/Swiss-Prot
  AMP-bd_C_sf UniProtKB/Swiss-Prot
  AMP-binding_CS UniProtKB/Swiss-Prot
  AMP-dep_Synth/Lig UniProtKB/Swiss-Prot
  AMP-dep_Synthh-like_sf UniProtKB/Swiss-Prot
  FATP5 UniProtKB/Swiss-Prot
KEGG Report rno:79111 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108681 IMAGE-MGC_LOAD
NCBI Gene 79111 ENTREZGENE
PANTHER PTHR43107:SF4 UniProtKB/Swiss-Prot
Pfam AMP-binding UniProtKB/Swiss-Prot
  AMP-binding_C UniProtKB/Swiss-Prot
PhenoGen Slc27a5 PhenoGen
PROSITE AMP_BINDING UniProtKB/Swiss-Prot
UniProt Q9ES38 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc27a5  solute carrier family 27 member 5  Slc27a5  solute carrier family 27 (fatty acid transporter), member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Slc27a5  solute carrier family 27 (fatty acid transporter), member 5    bile acid CoA ligase  Name updated 1299863 APPROVED
2004-09-10 Slc27a5  bile acid CoA ligase  LOC79111    Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference