Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ENOX1 mRNA | CTD | PMID:23649840 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ENOX1 mRNA | CTD | PMID:32109520 | 2-palmitoylglycerol | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ENOX1 mRNA | CTD | PMID:37199045 | 3-chloropropane-1,2-diol | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | alpha-Chlorohydrin results in decreased expression of ENOX1 mRNA | CTD | PMID:35690182 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of ENOX1 gene | CTD | PMID:31601247 | 5-aza-2'-deoxycytidine | multiple interactions | ISO | ENOX1 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Decitabine results in decreased expression of ENOX1 mRNA] | CTD | PMID:19363521 | 5-aza-2'-deoxycytidine | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Decitabine results in decreased expression of ENOX1 mRNA | CTD | PMID:19363521 | 7,12-dimethyltetraphene | decreases expression | ISO | Enox1 (Mus musculus) | 6480464 | 9 more ... | CTD | PMID:32553695 | 8-Br-cAMP | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ENOX1 mRNA | CTD | PMID:20147733 | aflatoxin B1 | affects expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ENOX1 protein | CTD | PMID:20106945 | aflatoxin B1 | affects methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of ENOX1 intron | CTD | PMID:30157460 | aflatoxin B1 | decreases methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ENOX1 gene | CTD | PMID:27153756 | aflatoxin B1 | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ENOX1 mRNA | CTD | PMID:22100608 more ... | benzo[a]pyrene | increases methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ENOX1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ENOX1 mRNA | CTD | PMID:32234424 and PMID:35690182 | benzo[a]pyrene | affects methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ENOX1 5' UTR and Benzo(a)pyrene affects the methylation of ENOX1 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | decreases methylation | ISO | Enox1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of ENOX1 intron | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ENOX1 mRNA | CTD | PMID:30816183 | bisphenol A | decreases methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ENOX1 gene | CTD | PMID:31601247 | carbamazepine | affects expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ENOX1 mRNA | CTD | PMID:25979313 | choline | multiple interactions | ISO | Enox1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ENOX1 gene | CTD | PMID:20938992 | clothianidin | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | clothianidin results in increased expression of ENOX1 mRNA | CTD | PMID:35690182 | dexamethasone | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of ENOX1 mRNA | CTD | PMID:25047013 | diquat | increases expression | ISO | Enox1 (Mus musculus) | 6480464 | Diquat results in increased expression of ENOX1 mRNA | CTD | PMID:36851058 | dorsomorphin | multiple interactions | ISO | ENOX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ENOX1 mRNA | CTD | PMID:29803840 | fenamidone | decreases expression | ISO | Enox1 (Mus musculus) | 6480464 | fenamidone results in decreased expression of ENOX1 mRNA | CTD | PMID:27029645 | folic acid | multiple interactions | ISO | Enox1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ENOX1 gene | CTD | PMID:20938992 | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of ENOX1 gene | CTD | PMID:35440735 | L-methionine | multiple interactions | ISO | Enox1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ENOX1 gene | CTD | PMID:20938992 | Lasiocarpine | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | lasiocarpine results in decreased expression of ENOX1 mRNA | CTD | PMID:32234424 and PMID:35690182 | melphalan | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Melphalan results in decreased expression of ENOX1 mRNA | CTD | PMID:22363485 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Enox1 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of ENOX1 mRNA | CTD | PMID:22401849 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of ENOX1 gene | CTD | PMID:33148267 | N-Nitrosopyrrolidine | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of ENOX1 mRNA | CTD | PMID:32234424 and PMID:35690182 | O-methyleugenol | decreases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of ENOX1 mRNA | CTD | PMID:32234424 and PMID:35690182 | panobinostat | multiple interactions | ISO | ENOX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ENOX1 mRNA | CTD | PMID:27188386 | paracetamol | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ENOX1 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ENOX1 mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of ENOX1 mRNA | CTD | PMID:32680482 | perfluorooctanoic acid | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of ENOX1 mRNA | CTD | PMID:35690182 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of ENOX1 gene | CTD | PMID:33148267 | phenylmercury acetate | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of ENOX1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | ENOX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ENOX1 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Enox1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ENOX1 mRNA | CTD | PMID:20813756 | pirinixic acid | multiple interactions | ISO | Enox1 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of ENOX1 mRNA | CTD | PMID:20813756 | potassium dichromate | decreases expression | ISO | Enox1 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of ENOX1 mRNA | CTD | PMID:23608068 | propanal | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of ENOX1 mRNA | CTD | PMID:26079696 | SB 431542 | multiple interactions | ISO | ENOX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | Enox1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of ENOX1 mRNA | CTD | PMID:37682722 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ENOX1 mRNA | CTD | PMID:31150632 | titanium dioxide | increases expression | ISO | Enox1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ENOX1 mRNA | CTD | PMID:23131501 | trichostatin A | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ENOX1 mRNA | CTD | PMID:24935251 | triptonide | increases expression | ISO | Enox1 (Mus musculus) | 6480464 | triptonide results in increased expression of ENOX1 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | Enox1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ENOX1 mRNA | CTD | PMID:17292431 | valproic acid | decreases methylation | ISO | ENOX1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ENOX1 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ENOX1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ENOX1 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ENOX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ENOX1 mRNA | CTD | PMID:27188386 | vincristine | increases expression | ISO | ENOX1 (Homo sapiens) | 6480464 | Vincristine results in increased expression of ENOX1 mRNA | CTD | PMID:23649840 | |