Enox1 (ecto-NOX disulfide-thiol exchanger 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Enox1 (ecto-NOX disulfide-thiol exchanger 1) Rattus norvegicus
Analyze
Symbol: Enox1
Name: ecto-NOX disulfide-thiol exchanger 1
RGD ID: 1306118
Description: Predicted to enable NADH dehydrogenase activity; protein disulfide isomerase activity; and protein-disulfide reductase activity. Predicted to be involved in ultradian rhythm. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Orthologous to human ENOX1 (ecto-NOX disulfide-thiol exchanger 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; N,N-diethyl-m-toluamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC306038; RGD1306118; similar to hypothetical protein FLJ31846
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Enox1Tn(sb-T2/Bart3)2.282Mcwi  
Genetic Models: F344-Enox1Tn(sb-T2/Bart3)2.282Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21552,517,833 - 53,079,752 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1552,515,178 - 53,079,749 (+)Ensembl
Rnor_6.01559,331,134 - 59,884,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1559,678,165 - 59,884,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01563,013,519 - 63,564,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41558,555,747 - 58,762,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11558,529,976 - 58,778,210 (+)NCBI
Celera1552,128,810 - 52,677,995 (+)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Comparative Map Data
Enox1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21552,517,833 - 53,079,752 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1552,515,178 - 53,079,749 (+)Ensembl
Rnor_6.01559,331,134 - 59,884,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1559,678,165 - 59,884,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01563,013,519 - 63,564,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41558,555,747 - 58,762,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11558,529,976 - 58,778,210 (+)NCBI
Celera1552,128,810 - 52,677,995 (+)NCBICelera
Cytogenetic Map15q11NCBI
ENOX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381343,213,130 - 43,786,972 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1343,213,130 - 43,786,972 (-)EnsemblGRCh38hg38GRCh38
GRCh371343,787,266 - 44,361,108 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361342,685,704 - 43,139,655 (-)NCBINCBI36hg18NCBI36
Celera1324,843,864 - 25,417,275 (-)NCBI
Cytogenetic Map13q14.11NCBI
HuRef1324,589,879 - 25,163,216 (-)NCBIHuRef
CHM1_11343,755,216 - 44,328,614 (-)NCBICHM1_1
T2T-CHM13v2.01342,431,573 - 43,005,924 (-)NCBI
Enox1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391477,393,790 - 77,959,203 (+)NCBIGRCm39mm39
GRCm39 Ensembl1477,394,203 - 77,959,200 (+)Ensembl
GRCm381477,156,248 - 77,721,763 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1477,156,763 - 77,721,760 (+)EnsemblGRCm38mm10GRCm38
MGSCv371477,556,623 - 78,121,214 (+)NCBIGRCm37mm9NCBIm37
MGSCv361475,890,971 - 76,455,562 (+)NCBImm8
Celera1474,659,159 - 75,225,482 (+)NCBICelera
Cytogenetic Map14D3NCBI
Enox1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555181,124,556 - 1,352,203 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555181,124,556 - 1,677,025 (-)NCBIChiLan1.0ChiLan1.0
ENOX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13199,336,885 - 199,480,415 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01324,377,918 - 24,722,036 (-)NCBIMhudiblu_PPA_v0panPan3
ENOX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1227,093,885 - 7,642,984 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl227,259,071 - 7,673,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha227,086,398 - 7,636,064 (+)NCBI
ROS_Cfam_1.0227,298,066 - 7,847,902 (+)NCBI
ROS_Cfam_1.0 Ensembl227,299,036 - 7,847,518 (+)Ensembl
UMICH_Zoey_3.1226,998,022 - 7,552,915 (+)NCBI
UNSW_CanFamBas_1.0227,059,909 - 7,610,039 (+)NCBI
UU_Cfam_GSD_1.0227,065,889 - 7,620,498 (+)NCBI
Enox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945153,364,591 - 153,885,764 (-)NCBI
SpeTri2.0NW_004936747380,813 - 709,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENOX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1123,237,697 - 23,894,727 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11123,234,764 - 23,894,763 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21123,830,914 - 24,285,421 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENOX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1321,339,684 - 21,909,377 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl321,339,690 - 21,545,310 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605722,275,637 - 22,852,341 (+)NCBIVero_WHO_p1.0
Enox1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474811,687,743 - 11,888,126 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474811,308,948 - 11,887,738 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D15Rat20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,813,028 - 52,813,179 (+)MAPPERmRatBN7.2
Rnor_6.01559,616,275 - 59,616,425NCBIRnor6.0
Rnor_5.01563,298,793 - 63,298,943UniSTSRnor5.0
RGSC_v3.41558,377,066 - 58,377,355RGDRGSC3.4
RGSC_v3.41558,377,126 - 58,377,276UniSTSRGSC3.4
RGSC_v3.11558,392,906 - 58,393,056RGD
Celera1552,413,673 - 52,413,823UniSTS
RH 3.4 Map15467.1UniSTS
RH 3.4 Map15467.1RGD
SHRSP x BN Map1535.7899UniSTS
SHRSP x BN Map1535.7899RGD
Cytogenetic Map15q11UniSTS
D15Rat123  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,847,908 - 52,848,045 (+)MAPPERmRatBN7.2
Rnor_6.01559,651,151 - 59,651,287NCBIRnor6.0
Rnor_5.01563,333,669 - 63,333,805UniSTSRnor5.0
RGSC_v3.41558,412,001 - 58,412,138RGDRGSC3.4
RGSC_v3.41558,412,002 - 58,412,138UniSTSRGSC3.4
RGSC_v3.11558,427,782 - 58,427,918RGD
Celera1552,448,507 - 52,448,643UniSTS
RH 3.4 Map15466.9UniSTS
RH 3.4 Map15466.9RGD
SHRSP x BN Map1535.7498UniSTS
SHRSP x BN Map1535.7498RGD
Cytogenetic Map15q11UniSTS
BE096152  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,406,331 - 52,406,500 (+)MAPPERmRatBN7.2
Rnor_6.01559,215,607 - 59,215,775NCBIRnor6.0
Rnor_5.01562,898,033 - 62,898,201UniSTSRnor5.0
RGSC_v3.41558,495,986 - 58,496,154UniSTSRGSC3.4
Celera1552,017,018 - 52,017,186UniSTS
RH 3.4 Map15494.11UniSTS
Cytogenetic Map15q11UniSTS
RH128801  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,839,600 - 52,839,783 (+)MAPPERmRatBN7.2
Rnor_6.01559,642,843 - 59,643,025NCBIRnor6.0
Rnor_5.01563,325,361 - 63,325,543UniSTSRnor5.0
RGSC_v3.41558,403,694 - 58,403,876UniSTSRGSC3.4
Celera1552,440,199 - 52,440,381UniSTS
RH 3.4 Map15466.6UniSTS
Cytogenetic Map15q11UniSTS
RH133019  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,908,424 - 52,908,606 (+)MAPPERmRatBN7.2
Rnor_6.01559,714,016 - 59,714,197NCBIRnor6.0
Rnor_5.01563,394,442 - 63,394,623UniSTSRnor5.0
RGSC_v3.41558,591,451 - 58,591,632UniSTSRGSC3.4
Celera1552,508,723 - 52,508,904UniSTS
RH 3.4 Map15464.19UniSTS
Cytogenetic Map15q11UniSTS
BE119345  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,959,137 - 52,959,346 (+)MAPPERmRatBN7.2
Rnor_6.01559,764,556 - 59,764,764NCBIRnor6.0
Rnor_5.01563,444,982 - 63,445,190UniSTSRnor5.0
RGSC_v3.41558,642,162 - 58,642,370UniSTSRGSC3.4
Celera1552,558,697 - 52,558,905UniSTS
RH 3.4 Map15466.9UniSTS
Cytogenetic Map15q11UniSTS
BF418003  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21552,884,602 - 52,884,723 (+)MAPPERmRatBN7.2
Rnor_6.01559,690,196 - 59,690,316NCBIRnor6.0
Rnor_5.01563,370,622 - 63,370,742UniSTSRnor5.0
RGSC_v3.41558,567,631 - 58,567,751UniSTSRGSC3.4
Celera1552,484,903 - 52,485,023UniSTS
RH 3.4 Map15466.9UniSTS
Cytogenetic Map15q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)155284790873690657Rat


Genetic Models
This gene Enox1 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:660
Count of miRNA genes:264
Interacting mature miRNAs:334
Transcripts:ENSRNOT00000073481, ENSRNOT00000074868
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 63 3
Low 3 43 20 12 11 12 8 9 11 35 38 11 8
Below cutoff 32 27 8 27 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000074868   ⟹   ENSRNOP00000065000
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1552,518,534 - 53,079,749 (+)Ensembl
Rnor_6.0 Ensembl1559,678,165 - 59,884,511 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110778   ⟹   ENSRNOP00000081296
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1552,515,178 - 53,079,749 (+)Ensembl
RefSeq Acc Id: XM_017599959   ⟹   XP_017455448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,716,855 - 53,079,752 (+)NCBI
Rnor_6.01559,609,147 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599960   ⟹   XP_017455449
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,517,835 - 53,079,752 (+)NCBI
Rnor_6.01559,331,134 - 59,884,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094030   ⟹   XP_038949958
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,517,834 - 53,079,752 (+)NCBI
RefSeq Acc Id: XM_039094031   ⟹   XP_038949959
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,517,834 - 53,079,752 (+)NCBI
RefSeq Acc Id: XM_039094032   ⟹   XP_038949960
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,729,263 - 53,079,752 (+)NCBI
RefSeq Acc Id: XM_039094033   ⟹   XP_038949961
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,517,833 - 53,079,752 (+)NCBI
RefSeq Acc Id: XM_039094034   ⟹   XP_038949962
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21552,517,834 - 52,975,431 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_017455449   ⟸   XM_017599960
- Peptide Label: isoform X3
- UniProtKB: D3ZYM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455448   ⟸   XM_017599959
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000065000   ⟸   ENSRNOT00000074868
RefSeq Acc Id: XP_038949961   ⟸   XM_039094033
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949958   ⟸   XM_039094030
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949959   ⟸   XM_039094031
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949962   ⟸   XM_039094034
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038949960   ⟸   XM_039094032
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000081296   ⟸   ENSRNOT00000110778

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYM3-F1-model_v2 AlphaFold D3ZYM3 1-643 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306118 AgrOrtholog
BioCyc Gene G2FUF-13031 BioCyc
Ensembl Genes ENSRNOG00000047817 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000065000 ENTREZGENE
  ENSRNOP00000065000.2 UniProtKB/TrEMBL
  ENSRNOP00000081296 ENTREZGENE
  ENSRNOP00000081296.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074868 ENTREZGENE
  ENSRNOT00000074868.3 UniProtKB/TrEMBL
  ENSRNOT00000110778 ENTREZGENE
  ENSRNOT00000110778.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro ENOX UniProtKB/TrEMBL
  ENOX_RRM UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene 306038 ENTREZGENE
PANTHER PTHR16001 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Enox1 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I6G7S4_RAT UniProtKB/TrEMBL
  D3ZYM3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Enox1  ecto-NOX disulfide-thiol exchanger 1  LOC100363621  hypothetical protein LOC100363621  Data Merged 1643240 APPROVED
2010-05-06 LOC100363621  hypothetical protein LOC100363621      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Enox1  ecto-NOX disulfide-thiol exchanger 1  RGD1306118_predicted  similar to hypothetical protein FLJ31846 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 RGD1306118_predicted  similar to hypothetical protein FLJ31846 (predicted)  LOC684954  similar to CG10948-PC, isoform C  Data Merged 1643240 APPROVED
2006-11-19 LOC684954  similar to CG10948-PC, isoform C      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1306118_predicted  similar to hypothetical protein FLJ31846 (predicted)  LOC306038_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC306038_predicted  similar to hypothetical protein FLJ31846 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL