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Strain: SD-Tbc1d1Tn(sb)1Fkh

Symbol: SD-Tbc1d1Tn(sb)1Fkh
Strain: SD-Tbc1d1Tn(sb)1
Substrain: Fkh
RGD ID: 150521708
Citation ID: RRID:RGD_150521708
Ontology ID: RS:0005114
Alleles: Tbc1d1Tn(sb)1Fkh
Also Known As: TBC1D1 KO rat; SD-Tbc1d1Tn(sb)Fkh; SD-Tbc1d1^[Tn(sb)1Fkh]
Type: mutant
Available Source: Not Available
Origination: University of Texas Southwestern Medical Center, Dallas TX
Description: The Sleeping Beauty transposon-mediated mutagenesis was used to knock out the rat Tbc1d1 gene in in rat spermatogonial stem cells from Sprague Dawley.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,936,820 - 44,135,133RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01445,598,753 - 45,797,650RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01445,404,208 - 45,603,325RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41446,594,874 - 46,781,813RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. The Rab-GTPase activating protein, TBC1D1, is critical for maintaining normal glucose homeostasis and β-cell mass. Paglialunga S, etal., Appl Physiol Nutr Metab. 2017 Jun;42(6):647-655. doi: 10.1139/apnm-2016-0585. Epub 2017 Jan 31.
2. Strains registration through online submission tool Strains registered through the Online Strain Submission Tool
3. Ablating the protein TBC1D1 impairs contraction-induced sarcolemmal glucose transporter 4 redistribution but not insulin-mediated responses in rats. Whitfield J, etal., J Biol Chem. 2017 Oct 6;292(40):16653-16664. doi: 10.1074/jbc.M117.806786. Epub 2017 Aug 14.


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-16 SD-Tbc1d1Tn(sb)1Fkh    SD-Tbc1d1Tn(sb)Fkh    Symbol and/or name change 68913 APPROVED