Bmpr2 (bone morphogenetic protein receptor type 2)

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Gene: Bmpr2 (bone morphogenetic protein receptor type 2) Rattus norvegicus

Analyze

Symbol:

Bmpr2

Name:

bone morphogenetic protein receptor type 2

RGD ID:

71082

Description:

Exhibits growth factor binding activity. Involved in brain development and retina development in camera-type eye. Localizes to several cellular components, including apical plasma membrane; basal plasma membrane; and caveola. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Bmpr-II; bone morphogenetic protein receptor type II; bone morphogenetic protein receptor type II (serine/threonine kinase); bone morphogenetic protein receptor type-2; bone morphogenetic protein receptor, type II (serine/threonine kinase); bone morphogenic protein receptor, type II (serine/threonine kinase)

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Allele / Splice:

Bmpr2^em1Sage Bmpr2^em2Sage Bmpr2^em1Ang

Genetic Models:

SD-Bmpr2^em1Ang+/- F344-Bmpr2^em2Sage+/- F344-Bmpr2^em1Sage+/-

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	61,192,718 - 61,307,280 (+)	NCBI
Rnor_6.0 Ensembl	9	66,568,074 - 66,676,494 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	9	66,568,074 - 66,683,019 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	9	66,371,542 - 66,486,121 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	58,327,587 - 58,436,057 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	58,524,438 - 58,554,549 (+)	NCBI
Celera	9	58,627,253 - 58,735,336 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

Brain Injuries (IEP)

Breast Neoplasms (ISO)

epilepsy (ISO)

Experimental Diabetes Mellitus (IEP)

Femoral Fractures (IEP)

heart septal defect (ISO)

hyperandrogenism (ISO)

Neurodevelopmental Disorders (ISO)

peripheral vascular disease (ISO)

primary pulmonary hypertension (ISO)

Primary Pulmonary Hypertension, 1 (ISO)

Pulmonary Arterial Hypertension (ISO)

pulmonary hypertension (IEP,IMP,ISO)

pulmonary venoocclusive disease (ISO)

Pulmonary Venoocclusive Disease 1 (ISO)

Reperfusion Injury (IEP)

Vascular Remodeling (IMP)

visual epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-methylcholine (ISO)

3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine (EXP)

3,4-methylenedioxymethamphetamine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (EXP,ISO)

arsenic atom (EXP,ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGS 15943 (ISO)

chloroprene (EXP)

choline (ISO)

chrysene (ISO)

clobetasol (ISO)

cobalt dichloride (ISO)

cocaine (EXP)

coumestrol (ISO)

crotonaldehyde (ISO)

cyclosporin A (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

diuron (EXP)

dorsomorphin (ISO)

Enterolactone (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenfluramine (ISO)

fluoxetine (EXP)

folic acid (ISO)

fosinopril (EXP)

iloprost (ISO)

L-methionine (ISO)

mercury atom (ISO)

mercury dichloride (ISO)

mercury(0) (ISO)

methacholine chloride (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

miconazole (ISO)

monocrotaline (EXP)

nitrofen (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

resveratrol (ISO)

Rutecarpine (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

simvastatin (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

taurine (ISO)

tetrachloroethene (ISO)

tetraphene (ISO)

titanium dioxide (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior/posterior pattern specification (ISO)

aortic valve development (ISO)

artery development (ISO)

atrial septum morphogenesis (ISO)

atrioventricular valve morphogenesis (ISO)

blood vessel development (IBA)

blood vessel remodeling (ISO)

BMP signaling pathway (IBA,ISO)

brain development (IEP)

cardiac muscle tissue development (ISO)

cellular response to BMP stimulus (ISO)

cellular response to growth factor stimulus (IBA)

cellular response to starvation (ISO)

chondrocyte development (ISO)

endocardial cushion development (ISO)

endochondral bone morphogenesis (ISS)

endothelial cell apoptotic process (ISO)

endothelial cell proliferation (ISO)

limb development (ISO)

lung alveolus development (ISO)

lymphangiogenesis (ISO)

lymphatic endothelial cell differentiation (ISO)

maternal placenta development (ISO)

mesoderm formation (ISO)

mitral valve morphogenesis (ISO)

negative regulation of cell growth (ISO)

negative regulation of cell proliferation involved in heart valve morphogenesis (ISO)

negative regulation of chondrocyte proliferation (ISO)

negative regulation of DNA biosynthetic process (ISO)

negative regulation of muscle cell differentiation (ISO)

negative regulation of systemic arterial blood pressure (ISO)

negative regulation of vasoconstriction (ISO)

osteoblast differentiation (ISO)

outflow tract morphogenesis (ISO)

outflow tract septum morphogenesis (ISO)

pharyngeal arch artery morphogenesis (ISO)

positive regulation of axon extension involved in axon guidance (ISO)

positive regulation of BMP signaling pathway (ISO)

positive regulation of bone mineralization (ISO)

positive regulation of cartilage development (ISS)

positive regulation of endothelial cell migration (ISO)

positive regulation of endothelial cell proliferation (ISO)

positive regulation of epithelial cell migration (ISO)

positive regulation of ossification (ISO)

positive regulation of osteoblast differentiation (ISO)

positive regulation of pathway-restricted SMAD protein phosphorylation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

protein phosphorylation (IBA)

proteoglycan biosynthetic process (ISS)

pulmonary valve development (ISO)

regulation of cell population proliferation (ISO)

regulation of lung blood pressure (ISO)

retina development in camera-type eye (IEP)

retina vasculature development in camera-type eye (ISO)

semi-lunar valve development (ISO)

transmembrane receptor protein serine/threonine kinase signaling pathway (ISO)

tricuspid valve morphogenesis (ISO)

venous blood vessel development (ISO)

ventricular septum morphogenesis (ISO)

Cellular Component

adherens junction (ISO)

apical plasma membrane (IDA)

basal plasma membrane (IDA)

caveola (IDA,ISO)

cell surface (ISO)

clathrin-coated pit (ISO)

cytoplasm (IDA)

dendrite (IDA)

integral component of plasma membrane (ISO)

neuronal cell body (IDA)

nucleoplasm (IEA,ISO)

plasma membrane (IBA,ISO)

postsynaptic density (ISO)

receptor complex (IBA)

Molecular Function

ATP binding (IEA)

BMP binding (ISO)

BMP receptor activity (ISO)

cadherin binding (ISO)

growth factor binding (IDA)

protein binding (ISO)

protein serine/threonine kinase activity (IBA,ISO)

protein tyrosine kinase binding (ISO)

transforming growth factor beta-activated receptor activity (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

Bone morphogenetic proteins signaling pathway (IMP,ISO)

cytokine mediated signaling pathway (IEA)

transforming growth factor-beta superfamily mediated signaling pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

vascular smooth muscle hypertrophy (IMP)

References

References - curated


1.	Austin ED, etal., Respir Res. 2009 Sep 28;10:87.
2.	Bosukonda D, etal., Kidney Int. 2000 Nov;58(5):1902-11.
3.	Charytoniuk DA, etal., Neuroscience. 2000;100(1):33-43.
4.	Cogan JD, etal., Genet Med. 2005 Mar;7(3):169-74.
5.	Dewachter L, etal., Eur Respir J. 2009 Nov;34(5):1100-10. Epub 2009 Mar 26.
6.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Girerd B, etal., Respir Res. 2010 Jun 10;11:73.
8.	GOA data from the GO Consortium
9.	Hong KH, etal., Circulation. 2008 Aug 12;118(7):722-30. Epub 2008 Jul 28.
10.	Kariyawasam HH, etal., Am J Respir Crit Care Med. 2008 May 15;177(10):1074-81. Epub 2008 Feb 21.
11.	Lewen A, etal., Neuroreport. 1997 Jan 20;8(2):475-9.
12.	Lopez-Lopez JG, etal., J Pharmacol Exp Ther. 2011 Jul;338(1):400-7. Epub 2011 Apr 26.
13.	MGD data from the GO Consortium
14.	Miyagi M, etal., Neuroscience. 2011 Mar 10;176:93-109. Epub 2010 Dec 23.
15.	Moller T, etal., Scand Cardiovasc J. 2010 Dec;44(6):331-6. Epub 2010 Nov 11.
16.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
17.	OMIM Disease Annotation Pipeline
18.	Onishi T, etal., Bone. 1998 Jun;22(6):605-12.
19.	Pipeline to import KEGG annotations from KEGG into RGD
20.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
21.	Ramos M, etal., Vascul Pharmacol. 2006 Jan;44(1):50-9. Epub 2005 Nov 3.
22.	Ranchoux B, etal., Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.
23.	Reynolds AM, etal., Eur Respir J. 2012 Feb;39(2):329-43. doi: 10.1183/09031936.00187310. Epub 2011 Jul 7.
24.	RGD automated data pipeline
25.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26.	RGD automated import pipeline for gene-chemical interactions
27.	RGD comprehensive gene curation
28.	Soderstrom S, etal., Cell Tissue Res. 1996 Nov;286(2):269-79.
29.	Takahashi H, etal., Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L450-8. Epub 2005 Dec 16.
30.	Tian W, etal., Circulation. 2019 Aug 29. doi: 10.1161/CIRCULATIONAHA.119.040629.
31.	Wang H, etal., Clin Genet. 2010 Feb;77(2):189-92. Epub 2009 Dec 10.
32.	West J, etal., Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L744-55. Epub 2008 Aug 22.
33.	Yamada H, etal., Jpn J Ophthalmol. 1999 Jul-Aug;43(4):290-4.

Additional References at PubMed

PMID:9442116	PMID:10772805	PMID:11502704	PMID:12045205	PMID:12117821	PMID:12441304	PMID:12819188	PMID:15542835	PMID:15657086	PMID:17114649	PMID:17472960	PMID:17992660
PMID:18063682	PMID:18326817	PMID:18364108	PMID:18367643	PMID:18436533	PMID:18552156	PMID:19153267	PMID:19366699	PMID:19409885	PMID:19440953	PMID:19669850	PMID:19903896
PMID:21619414	PMID:21976273	PMID:22664934	PMID:23079343	PMID:23446737	PMID:23610558	PMID:23676498	PMID:23780850	PMID:24052814	PMID:25187962	PMID:25461595	PMID:25468996
PMID:26076038	PMID:26535780	PMID:26598555	PMID:26774823	PMID:27177866	PMID:27622883	PMID:28187784	PMID:29478969	PMID:30575923	PMID:30586714	PMID:30610955	PMID:31850803

Genomics

Comparative Map Data

Bmpr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	61,192,718 - 61,307,280 (+)	NCBI
Rnor_6.0 Ensembl	9	66,568,074 - 66,676,494 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	9	66,568,074 - 66,683,019 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	9	66,371,542 - 66,486,121 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	58,327,587 - 58,436,057 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	58,524,438 - 58,554,549 (+)	NCBI
Celera	9	58,627,253 - 58,735,336 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

BMPR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	202,376,327 - 202,567,751 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	202,376,310 - 202,567,751 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	203,241,050 - 203,432,472 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	2	203,241,033 - 203,432,474 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	202,949,916 - 203,140,719 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	203,067,104 - 203,257,979	NCBI
Celera	2	196,992,827 - 197,184,404 (+)	NCBI
Cytogenetic Map	2	q33.1-q33.2	NCBI
HuRef	2	195,088,272 - 195,279,312 (+)	NCBI		HuRef
CHM1_1	2	203,247,530 - 203,439,226 (+)	NCBI		CHM1_1

Bmpr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	59,802,721 - 59,917,240 (+)	NCBI	GRCm39		mm39
GRCm38	1	59,764,279 - 59,878,081 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	59,763,400 - 59,879,014 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	59,821,481 - 59,927,703 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	59,709,183 - 59,815,405 (+)	NCBI			mm8
Celera	1	60,279,442 - 60,385,822 (+)	NCBI		Celera
Cytogenetic Map	1	C2	NCBI
cM Map	1	30.44	NCBI

Bmpr2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	12,235,780 - 12,316,727 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955457	12,235,780 - 12,315,680 (-)	NCBI	ChiLan1.0	ChiLan1.0

BMPR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	207,780,568 - 207,968,900 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	207,780,741 - 207,961,072 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2B	89,631,622 - 89,823,438 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

BMPR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	37	11,342,384 - 11,533,024 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	37	11,342,292 - 11,540,199 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Bmpr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936726	1,543,263 - 1,711,422 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BMPR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	105,970,427 - 106,135,730 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	105,971,577 - 106,132,496 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	117,426,776 - 117,589,050 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BMPR2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	88,103,442 - 88,302,578 (+)	NCBI
ChlSab1.1 Ensembl	10	88,106,072 - 88,303,734 (+)	Ensembl

Bmpr2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624765	13,849,689 - 13,950,839 (-)	NCBI

Position Markers

RH134140

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	9	66,677,246 - 66,677,429	NCBI	Rnor6.0
Rnor_5.0	9	66,480,348 - 66,480,531	UniSTS	Rnor5.0
RGSC_v3.4	9	58,436,817 - 58,437,000	UniSTS	RGSC3.4
Celera	9	58,736,088 - 58,736,271	UniSTS
RH 3.4 Map	9	514.9	UniSTS
Cytogenetic Map	9	q31	UniSTS

BF403103

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	9	66,682,023 - 66,682,176	NCBI	Rnor6.0
Rnor_5.0	9	66,485,125 - 66,485,278	UniSTS	Rnor5.0
RGSC_v3.4	9	58,441,597 - 58,441,750	UniSTS	RGSC3.4
Celera	9	58,740,884 - 58,741,037	UniSTS
RH 3.4 Map	9	496.5	UniSTS
Cytogenetic Map	9	q31	UniSTS

AW536011

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	9	66,682,232 - 66,682,390	NCBI	Rnor6.0
Rnor_5.0	9	66,485,334 - 66,485,492	UniSTS	Rnor5.0
RGSC_v3.4	9	58,441,806 - 58,441,964	UniSTS	RGSC3.4
Celera	9	58,741,093 - 58,741,251	UniSTS
RH 3.4 Map	9	495.8	UniSTS
Cytogenetic Map	9	q31	UniSTS

RH141266

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	9	66,676,506 - 66,676,686	NCBI	Rnor6.0
Rnor_5.0	9	66,479,608 - 66,479,788	UniSTS	Rnor5.0
RGSC_v3.4	9	58,436,069 - 58,436,249	UniSTS	RGSC3.4
Celera	9	58,735,348 - 58,735,528	UniSTS
RH 3.4 Map	9	495.8	UniSTS
Cytogenetic Map	9	q31	UniSTS

AI009781

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	9	66,680,723 - 66,680,938	NCBI	Rnor6.0
Rnor_5.0	9	66,483,825 - 66,484,040	UniSTS	Rnor5.0
RGSC_v3.4	9	58,440,297 - 58,440,512	UniSTS	RGSC3.4
Celera	9	58,739,565 - 58,739,780	UniSTS
RH 3.4 Map	9	515.3	UniSTS
Cytogenetic Map	9	q31	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1055222	93442944	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	24885099	69885099	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	25692342	92741406	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	25692373	70692373	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	27486036	66757620	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	27486155	88333183	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	29075079	83686404	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	29075079	122095297	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	29466970	107878528	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	32385133	77385133	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	37642351	82642351	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	37642351	82642351	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	41261034	90024806	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	41261034	98606834	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	41261034	102531865	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	total urine protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	46579769	91579769	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	46579769	91579769	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	46952427	83686153	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	47248965	94124663	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	54177542	99177542	Rat
1598849	Memor17	Memory QTL 17	2.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	54885041	76677636	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	60810298	82732466	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	61186278	106186278	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61730923	82890620	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	61730923	82890620	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	61730923	82890620	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	63270073	107878387	Rat

Genetic Models

This gene Bmpr2 is modified in the following models/strains

SD-Bmpr2^em1Ang+/-

F344-Bmpr2^em2Sage+/-

F344-Bmpr2^em1Sage+/-

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	35
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000035238
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		40	29	13	16	13	8	8	74	34	37	11	8
Low	3	3	28	28	3	28		3		1	4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_080407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB073714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000035238 ⟹ ENSRNOP00000037011

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	9	66,568,074 - 66,676,494 (+)	Ensembl

RefSeq Acc Id:

NM_080407 ⟹ NP_536332

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	61,192,718 - 61,300,753 (+)	NCBI
Rnor_6.0	9	66,568,074 - 66,676,494 (+)	NCBI
Rnor_5.0	9	66,371,542 - 66,486,121 (+)	NCBI
RGSC_v3.4	9	58,327,587 - 58,436,057 (+)	RGD
Celera	9	58,627,253 - 58,735,336 (+)	RGD

Sequence:

show sequence

CACTCTGGATATGTTTTCTCCCAGATCTGGCTATTTTTTTGATATCGTGAAACTACGAGGGAAA
TAATTGCAGGGGTTTCTTCTGGGCTCCCTGCTTCTTCCCCACGGACATGCCTTCAGTTTGGGGA
ACCGAGGCACCCCGTCCTAGGCGAATGAAGCCCCCCAGCCACGAGGGAGCGAAATGAAGGGAAA
TTCTGCAGTGGAATGAGAGCTCTACAAGCTAGGTCCTCGCATCTGCCATTTGTCCTTTCAAACT
GCATTGTAATCCGGGCAGGATAAATCAGGAAGAGCAGCCTCCTGGCCGGATTTCTCACCCGAAT
TTACTTTCCTGATTTCTTTTCTTTGCCCTCCTGCTTCTTGGCTGGCCCAGGGATGACTTCCTCG
CTGCAGCGGCCCTTTCGGGTGCCCTGGCTGTTATGGGCCGTCCTGCTGGTCAGCACTACGGCTG
CTTCCCAGAATCAAGAACGGCTGTGTGCATTTAAAGACCCGTATCAACAAGACCTTGGGATTGG
TGAGAGTCGAATCTCTCATGAAAATGGGACAATATTATGCTCCAAAGGGAGCACATGTTATGGT
CTGTGGGAGAAATCAAAAGGGGACATCAATCTTGTGAAACAAGGGTGCTGGTCTCACATTGGTG
ATCCCCAAGAGTGCCACTATGAAGAATGTGTAGTAACTACCACCCCACCCTCAATTCAGAATGG
AACATACCGTTTTTGCTGCTGTAGTACAGACTTATGTAACGTCAACTTCACTGAGAACTTCCCA
CCTCCTGATACAACACCACTCAGTCCGCCTCATTCATCTAATCGGGATGAAACTATAATCATTG
CTTTGGCATCGGTTTCTGTATTAGCTGTTTTGATAGTCGCCTTATGTTTTGGATACAGAATGTT
GACAGGAGACAGGAAACAGGGTCTACACAGTGTGAGCATGATGGAGGCGGCAGCGGCAGAGCCC
TCCCTGGACTTGGATAACCTGAAGCTGCTGGAGCTGATTGGACGGGGTCGATATGGAGCAGTAT
ATAAAGGTTCCTTGGATGAGCGTCCAGTTGCTGTAAAAGTATTTTCTTTTGCAAACCGTCAGAA
TTTTATAAATGAAAAAAACATTTACAGAGTGCCTTTGATGGAACATGACAACATTGCTCGCTTT
ATAGTTGGAGACGAGAGGCTCACTGCAGATGGACGCATGGAGTATTTGCTTGTGATGGAGTATT
ATCCCAATGGATCTCTGTGCAAATATCTGAGTCTCCATACAAGTGATTGGGTAAGCTCTTGCCG
TCTGGCTCATTCTGTGACAAGAGGACTGGCTTATCTTCACACAGAATTACCCCGAGGAGATCAT
TACAAACCTGCAATTTCCCATCGAGATTTAAACAGCAGAAATGTCCTGGTAAAGAATGGTGGCA
CGTGTGTTATCAGTGACTTTGGTCTGTCCATGAGGCTAACTGGAAACAGGCTGGTGCGCCCAGG
GGAAGAAGATAACGCGGCTATAAGTGAGGTTGGCACAATCCGCTATATGGCACCAGAAGTGCTA
GAAGGAGCTGTGAACCTGAGGGACTGTGAGTCAGCACTGAAGCAAGTGGACATGTATGCGCTTG
GACTGATCTACTGGGAGGTGTTTATGAGGTGCACAGACCTCTTCCCAGGTGAATCTGTACCAGA
TTACCAGATGGCTTTTCAGACAGAAGTTGGAAACCATCCCACATTTGAGGATATGCAGGTTCTT
GTGTCAAGAGAAAAGCAGAGACCCAAGTTCCCAGAAGCCTGGAAAGAAAATAGCCTGGCAGTGA
GGTCACTCAAAGAAACAATCGAAGACTGCTGGGACCAGGATGCAGAGGCTCGGCTCACTGCACA
GTGTGCTGAGGAGAGAATGGCTGAACTCATGATGATATGGGAGAGAAACAAGTCTGTGAGCCCA
ACGGTCAACCCAATGTCGACTGCTATGCAGAACGAACGCAACCTATCACATAATAGGCGTGTGC
CAAAAATCGGGCCTTACCCAGATTATTCCTCTTCCTCATATATTGAAGACTCAATTCATCACAC
TGACAGCATTGTGAAAAATATTTCCTCTGAGCATTCAATGTCCAGCACACCGTTGACAATAGGA
GAAAAGAACCGAAACTCAATTAATTATGAACGACAGCAAGCACAAGCTCGAATCCCTAGCCCAG
AAACAAGCGTCACAAGCCTGTCCACAAACACAACCACCACAAACACCTCTGGCCTCACTCCAAG
TACTGGCATGACCACGATATCTGAGATGCCATACCCAGATGAGACACATTTGCATGCCACAAAT
GTTGCACAGTCACTCGGGCCAACCCCTGTCTGCTTACAGCTGACAGAAGAAGACTTGGAAACTA
ATAAGCTAGACCCAAAAGAAGTTGATAAGAACCTCAAGGAAAGCTCTGATGAGAATCTCATGGA
GCATTCTCTGAAGCAGTTCAGTGGGCCAGACCCGTTGAGCAGTACCAGTTCCAGCTTGCTTTAT
CCACTCATAAAGCTTGCGGTGGAAGTGACTGGACAACAGGACTTCACACAGGCTGCAAATGGGC
AAGCATGTTTAATTCCTGATGTCCCACCTGCTCAGCTCTATCCTCTCCCTAAGCAACAGAACCT
TCCGAAGAGACCTACTAGTTTGCCTTTGAACACCAAAAATTCAACTAAAGAACCCCGGCTAAAA
TTTGGCAACAAGCACAAATCAAACTTGAAACAAGTAGAAACTGGAGTTGCCAAGATGAATACAA
TCAATGCAGCAGAGCCTCATGTGGTGACAGTAACTATGAATGGTGTGGCAGGTAGAAGCCACAA
TGTTAATTCCCATGCTGCCACAACCCAGTATGCCAATGGGGTAGTGCCATCTGGCCAGGCAGCC
AACATAGTGGCACATAGGGCCCAAGAAATGCTGCAGAATCAATTTAATGGTGAGGATACCAGAC
TGAATATCAATTCCAGTCCTGATGAACATGAACCTTTACTGAGACGAGAGCAGCAGGCTGGCCA
TGATGAAGGGGTTCTGGATCGTTTGGTAGACAGGAGGGAACGGCCATTAGAAGGTGGCCGAACT
AATTCCAATAACAACAACAGCAATCCATGTTCAGAACAAGATGTCCCTACACAAGGTGTTACAA
GCACAGCTGCAGACCCTGGGCCAGCAAAGCCCAGAAGAGCACAGAGGCCCAATTCTCTGGATCT
TTCAGCCACAAATATCCTGGATGGCAGCAGCATGCAGATAGGTGAGTCAACGCAGGATGGCAAA
TCAGGATCAGGCGAAAAGATCAAGAGACGTGTGAAAACTCCATACTCTCTTAAGCGGTGGCGCC
CATCCACCTGGGTCATCTCCACCGAGCCACTGGACTGTGAGGTCAACAACAATGGCAGTGACAG
GGCAGTCCATTCTAAATCTAGCACTGCTGTGTACCTCGCAGAGGGAGGCACTGCCACAACCATG
GTGTCTAAAGATATAGGAATGAATTGTCTGTGAGATGTTTTCAAGCTTATGGAGTGAAATTATT
TTTTTGCATCATTTAAACATGCAGAAGACATTTTAAAAAAAAAAAAACTGCTTTAACCTCCTGT
CAGCACCCCTTCCCACCCCTGCAGCAAGGACTTGCTTTAAATAGATTTCAGCTATGCAGAAAAC
TTTAGCTTATGCTTCCATATTTTTTAATTTTGTTTTTTAAGTTTTGCACTTTTGTTTAGTCTTG
CTAAAGTTCTATTTGTCTGTTATGACCACATTATATGTGTGCTTATCAAAAGTGGTCTCAAAAT
ATTTTTTTTAAGAAAAAAAGCAAAAACAATGTATTGCTGATAATCAGTTTGGACCATTTTCTAA
AGGTCATTAAAACAGAAGCAAATTAAGAC

hide sequence

RefSeq Acc Id:

XM_006244951 ⟹ XP_006245013

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	61,193,040 - 61,307,280 (+)	NCBI
Rnor_6.0	9	66,568,427 - 66,683,019 (+)	NCBI
Rnor_5.0	9	66,371,542 - 66,486,121 (+)	NCBI

Sequence:

show sequence

CTTCTTGGCTGGCCCAGGGATGACTTCCTCGCTGCAGCGGCCCTTTCGGGTGCCCTGGCTGTTA
TGGGCCGTCCTGCTGGTCAGCACTACGGCTGAACTCTTGAACATCCTCAGCCTCCAACGTGCTG
GAATTACAGCTTCCCAGAATCAAGAACGGCTGTGTGCATTTAAAGACCCGTATCAACAAGACCT
TGGGATTGGTGAGAGTCGAATCTCTCATGAAAATGGGACAATATTATGCTCCAAAGGGAGCACA
TGTTATGGTCTGTGGGAGAAATCAAAAGGGGACATCAATCTTGTGAAACAAGGGTGCTGGTCTC
ACATTGGTGATCCCCAAGAGTGCCACTATGAAGAATGTGTAGTAACTACCACCCCACCCTCAAT
TCAGAATGGAACATACCGTTTTTGCTGCTGTAGTACAGACTTATGTAACGTCAACTTCACTGAG
AACTTCCCACCTCCTGATACAACACCACTCAGTCCGCCTCATTCATCTAATCGGGATGAAACTA
TAATCATTGCTTTGGCATCGGTTTCTGTATTAGCTGTTTTGATAGTCGCCTTATGTTTTGGATA
CAGAATGTTGACAGGAGACAGGAAACAGGGTCTACACAGTGTGAGCATGATGGAGGCGGCAGCG
GCAGAGCCCTCCCTGGACTTGGATAACCTGAAGCTGCTGGAGCTGATTGGACGGGGTCGATATG
GAGCAGTATATAAAGGTTCCTTGGATGAGCGTCCAGTTGCTGTAAAAGTATTTTCTTTTGCAAA
CCGTCAGAATTTTATAAATGAAAAAAACATTTACAGAGTGCCTTTGATGGAACATGACAACATT
GCTCGCTTTATAGTTGGAGACGAGAGGCTCACTGCAGATGGACGCATGGAGTATTTGCTTGTGA
TGGAGTATTATCCCAATGGATCTCTGTGCAAATATCTGAGTCTCCATACAAGTGATTGGGTAAG
CTCTTGCCGTCTGGCTCATTCTGTGACAAGAGGACTGGCTTATCTTCACACAGAATTACCCCGA
GGAGATCATTACAAACCTGCAATTTCCCATCGAGATTTAAACAGCAGAAATGTCCTGGTAAAGA
ATGGTGGCACGTGTGTTATCAGTGACTTTGGTCTGTCCATGAGGCTAACTGGAAACAGGCTGGT
GCGCCCAGGGGAAGAAGATAACGCGGCTATAAGTGAGGTTGGCACAATCCGCTATATGGCACCA
GAAGTGCTAGAAGGAGCTGTGAACCTGAGGGACTGTGAGTCAGCACTGAAGCAAGTGGACATGT
ATGCGCTTGGACTGATCTACTGGGAGGTGTTTATGAGGTGCACAGACCTCTTCCCAGGTGAATC
TGTACCAGATTACCAGATGGCTTTTCAGACAGAAGTTGGAAACCATCCCACATTTGAGGATATG
CAGGTTCTTGTGTCAAGAGAAAAGCAGAGACCCAAGTTCCCAGAAGCCTGGAAAGAAAATAGCC
TGGCAGTGAGGTCACTCAAAGAAACAATCGAAGACTGCTGGGACCAGGATGCAGAGGCTCGGCT
CACTGCACAGTGTGCTGAGGAGAGAATGGCTGAACTCATGATGATATGGGAGAGAAACAAGTCT
GTGAGCCCAACGGTCAACCCAATGTCGACTGCTATGCAGAACGAACGCAACCTATCACATAATA
GGCGTGTGCCAAAAATCGGGCCTTACCCAGATTATTCCTCTTCCTCATATATTGAAGACTCAAT
TCATCACACTGACAGCATTGTGAAAAATATTTCCTCTGAGCATTCAATGTCCAGCACACCGTTG
ACAATAGGAGAAAAGAACCGAAACTCAATTAATTATGAACGACAGCAAGCACAAGCTCGAATCC
CTAGCCCAGAAACAAGCGTCACAAGCCTGTCCACAAACACAACCACCACAAACACCTCTGGCCT
CACTCCAAGTACTGGCATGACCACGATATCTGAGATGCCATACCCAGATGAGACACATTTGCAT
GCCACAAATGTTGCACAGTCACTCGGGCCAACCCCTGTCTGCTTACAGCTGACAGAAGAAGACT
TGGAAACTAATAAGCTAGACCCAAAAGAAGTTGATAAGAACCTCAAGGAAAGCTCTGATGAGAA
TCTCATGGAGCATTCTCTGAAGCAGTTCAGTGGGCCAGACCCGTTGAGCAGTACCAGTTCCAGC
TTGCTTTATCCACTCATAAAGCTTGCGGTGGAAGTGACTGGACAACAGGACTTCACACAGGCTG
CAAATGGGCAAGCATGTTTAATTCCTGATGTCCCACCTGCTCAGCTCTATCCTCTCCCTAAGCA
ACAGAACCTTCCGAAGAGACCTACTAGTTTGCCTTTGAACACCAAAAATTCAACTAAAGAACCC
CGGCTAAAATTTGGCAACAAGCACAAATCAAACTTGAAACAAGTAGAAACTGGAGTTGCCAAGA
TGAATACAATCAATGCAGCAGAGCCTCATGTGGTGACAGTAACTATGAATGGTGTGGCAGGTAG
AAGCCACAATGTTAATTCCCATGCTGCCACAACCCAGTATGCCAATGGGGTAGTGCCATCTGGC
CAGGCAGCCAACATAGTGGCACATAGGGCCCAAGAAATGCTGCAGAATCAATTTAATGGTGAGG
ATACCAGACTGAATATCAATTCCAGTCCTGATGAACATGAACCTTTACTGAGACGAGAGCAGCA
GGCTGGCCATGATGAAGGGGTTCTGGATCGTTTGGTAGACAGGAGGGAACGGCCATTAGAAGGT
GGCCGAACTAATTCCAATAACAACAACAGCAATCCATGTTCAGAACAAGATGTCCCTACACAAG
GTGTTACAAGCACAGCTGCAGACCCTGGGCCAGCAAAGCCCAGAAGAGCACAGAGGCCCAATTC
TCTGGATCTTTCAGCCACAAATATCCTGGATGGCAGCAGCATGCAGATAGGTGAGTCAACGCAG
GATGGCAAATCAGGATCAGGCGAAAAGATCAAGAGACGTGTGAAAACTCCATACTCTCTTAAGC
GGTGGCGCCCATCCACCTGGGTCATCTCCACCGAGCCACTGGACTGTGAGGTCAACAACAATGG
CAGTGACAGGGCAGTCCATTCTAAATCTAGCACTGCTGTGTACCTCGCAGAGGGAGGCACTGCC
ACAACCATGGTGTCTAAAGATATAGGAATGAATTGTCTGTGAGATGTTTTCAAGCTTATGGAGT
GAAATTATTTTTTTGCATCATTTAAACATGCAGAAGACATTTTAAAAAAAAAAAAACTGCTTTA
ACCTCCTGTCAGCACCCCTTCCCACCCCTGGAGCAAGGACTTGCTTTAAATAGATTTCAGCTAT
GCAGAAAACTTTAGCTTATGCTTCCATATTTTTTAATTTTGTTTTTTAAGTTTTGCACTTTTGT
TTAGTCTTGCTAAAGTTCTATTTGTCTGTTATGACCACATTATATGTGTGCTTATCAAAAGTGG
TCTCAAAATATTTTTTTTAAGAAAAAAAGCAAAAACAATGTATTGCTGATAATCAGTTTGGACC
ATTTTCTAAAGGTCATTAAAACAGAAGCAAATTAAGACAGGTTTGACTGCAACGGTGTCTGGTA
TCCATGTTTTATTTCTGGGCACAAGCTAGTTTATATGTTAACGTGTTTTTGACCATAATCTGTT
GGACATTCTTCTGTGTTTTATTTGAATGTGCAATAGTCTGTAGACCACAAAGAAGCTTTCTCAT
CTGCTCTCTTCCTAGCAGGGCACACATTCTTCTTCCATTGTTGAAAGAAACATTTTCCCTGGTC
TTCGACAATATGAACATTTTCCAGCTTTCTCCTTATGGAGATGCTTAGACGCTGTCCAAAGGGC
TCCACACAGGACTTACCAAAACATGTATTGAGATGCCATTGTCTTCTAACCTTCCAGTGCTAAG
TGTTTCCTTCCAGGCATTTCACTAAGCATGTCTGGTTCTGGTTTTGGAAGCTCATAAGAGAGCA
TAGAACAAAACAGAGGAAAGCAAATATTAGCCTTCTCCCTTTTATTTTTCTATGTTTATGTTCA
TGTCTGTATTCATTATTTAAGAAGTATTTTTTATCAAAAAATGTATAGAGCTAAACCTACATGG
AATGTTTAAATAGCTGGGCAAAGTGATTAGTATAGTAACTTTCACTTTCTGACCGTCACAAATT
AAATCACATTTCCTATTTATAGTAACTTCAGGAGTAATCGAATCTATAGGATGGTTCCTTGTTT
CCCAGCACTGCCTGACAGTTCTATGTGAAAAAGTGATTCCTCCTCCTCCCGTGACCTAAAACAC
TGTGGAAAGCTCCAGCCAGCTCGCCAGATCCTATGGAAGAAAGGCTTGCTGCCAACTTAGGGCC
GTTGAGCAGACTAAGATTGGCCCTGTCTTTCCTAACTTCGTTCTTCACTGACTGCTTTTGTAGT
TTCTCCCTTTGCCAGTTTCACACGTTCTCTGATGGCGAGCAGCACTCACTGTTTGTCGTGATAG
AGCGTCTTCTGCTGACGATGTGCCGTGGCCTTGCTGTCACGATGCTTTTGCTTCTTTTGTCACT
AGTGATCTCTGAAACAACAGTCTCTGTGTCTTTTAATAAAGCACTTTCTGTCAAAAATTTTAGA
AAATTTCCCTAAACATTGCTTCCTATCAGTTTGTAGACACTGTTCTCATGGTTTTCAGATTCTC
AGAATCCTTAATATCCATTATCTGACTATGTTTTCAGTTTTAGCAGGAAGATAAAAAGTTAAGT
GCAAATCTCCAAAGTCCTGATTTTGGTTCTTCTGTCCTGAACCATTTTAATCCATTCTCATTTG
TAATCCTCTTTCCTTCCGTTTAACTCGTACCCGACCTGCCGTGCTTTGACGTGACAGCGTTTTC
CATGTAGTCAGCCGCAGCACTGACGAGAGCTCTCAGTTCTTAGGATTAGGATTGTCTTACCTGT
GCCCAGGACTCCTTTCTGACTTTTGTGTTTCATCGGCCCCTCTTGTGGTTCAGAGTCTTATATA
TATTTTTGTCTTCTCCATACAGTTGTTTTTGTTTTTGTTTTTTCTCTAGTTAGTTACTGCCCTT
TGTCTATGTAACAAATAATTTGAATCTTTCACTCATTTCTTTTGTCCAAATGGCTTTCAAATGC
ATTTCAGAATTTTTATTTTCCAATTGTATGACAACTTTAAATCATAATAAATTATATTCCTCCC
ATCTTCAATTTGAAACATTAAGAATAAATGACCCTTTGAGGTCCAACTGATCTTTTCCTATCAG
AAAAATTGTCTTACATTCTGATACAGTGTATATTAGGGCCAGTCAGTTTGAATTTTTCAAGTCT
TTAATGTTTAATAATAGAATGCTTCAAAAATTAATATGCCAGATAAAAGAAATCTCTATAGTTC
CCATCTCATGCAAATGTATTTAAAACAAATAATTCCTTGAACTGCTTGAAGAATAGGAAAGGTA
GTAAGTATAGGTCATTTTAATAAAATTTGAAATCTGTACTACACAGCATGCAGAAATCCCTTTA
ACACTAGTTAGATTTATTTAATCTGATTCTTGAGCCGAAATGGAATTTACCACAAAATTTCACA
CACAGAAATTAATTTTAGGCCTTTTGAATGAAAGTCATTTAATTTAAAAAGATTTCTAGGGACA
GTAATATAATAGGACATCAGAGTATGGTTAGTTCCCTTAAGAATATTCTAGTTGTGGGGCTGGA
GGGATGACATAATAATAACAGTGCTTCCTGCGCTTACAGAGGACCCAAGTTCAGTTCCCAGCAG
CTACATGGCAGCTCACAACTTCCACAGAATCCAATTCCCTCTTTTGGCCTCCACTGACATGCAC
ATAACACCATCCTACCCGCACACACACACACATGCACATAATTATAAATGACAACAGTAAACCT
TAAAATACTAGTTATATACCAGAGCTATGTGATGGAAATAACTTGATTTGAATTATGTATAGAG
TAAAATCATTTAAATAAAAATCCTAGCTAATTTAAATGTATAATTTAAAAAATACTGCTACTGT
AGAAGTTTGTGAAGACATGCTGAAAACTGGCATTACATACACTCATCTTTTCATTCTCAGAGCA
ACCATTATTATAATTAATATTCATATTTTACAAATGAGGAAATAAAAATTAAATGGAAATCTGT
CTGTTTCATCCCAGACATACCTGGGATTTCACCCTGGGTCTGTCTCTCCATGTGTCTTTTATGC
ACAACACATGGTCTACATTCTTTATGAGCTGATGTGCAGTGTCCTGACATGTTGTGCTCCAGCA
GACGTGTGGTTTGTGTGTAAGCCAGGCCAGGTTCCTTAATGATCTTAAGTTAGGTAAAGCTAAA
ACAGTTCCTAATTCAATACAAAATTCAGCCCACATCTCAACAGTCGTCTTACCTGTCTCCTAAT
ATTTTTACATTGCAGAAGAAAAGGGAAAGTAAATGCTAGGAGACAGTGAAGGGAGCAGATGGAG
CGGGAGCTCCCTAACGTGACCCCGTACCTCTCTCGGAAAGAAGACTTTTATGTAAACTTGCAGT
CTTCTCAATCCTTTGACTCCATCTTTAAAGCTTCAGTTTTACCAATGTTAGGAAAAAGTTGTTA
ATCCAGAGAACTAAATAATCTGTAGAGAGAGTAGAAGGTTAACATTCGCAGGCTTGTGGAGCTT
CTGGATGTGTGTATACTTTTTCCAGAACCTGTATGTTGGTTCTGAATATAAGGAACACTCAAAT
CAGTGGGAATTACAAATTTTATTTAAAATATTTCCAAGTTTGACTTCTGAATCCCAAAGGAAAA
TCTGATATGGTACAGCTAACCTGTTTACTCTCTGTTAATTAGTCATTTAAAGTGGAAAGAAAAT
AAACATTGGTTTCCTCTTGTCATGTTTATGGACATAAATATTTCACTGGGAGTCACTATTAGAA
TTTGATATTATATTTATCACATTTTATAAACCTATGTTGAGCTTAGTACCAGTCATGTATATGT
TATTATATGATTAGCCACAGGTTTTTGAAAATATATAATTACCTTATATCCTTAAGTCCTTAAA
AGATTCTGCACACATTCTAATTCTACTGTTCTAGACCAGCATTCTAGGATGTGTGTAACAACCC
CTTATAGGCCCTAGGAGCCTTTTAGGCTATAATAGTTTTAAATATTCACACCCTTGACTAGCAG
TGGGTTGTGGTGTATTTTGCTTTTCTTTTTAAGTTTTTTTTAGATTATGAACTATGCAAACTTC
ATCCAAAAACTACCTTTCATGATCCCTTCCTAACTGCTTTTTGATTCTTTCAGTCTAGCCAGCT
ACTTTCTGAACTACTTAACAAAGGTTATTATCAAAAAAGACTTTTCTATAAGTGTCCACATTAA
CACTGAGGAAATCTCCATGTGCCCAAAGAGGTGGTAACACCTACCTGTTCCTCTCTTTAAGTCC
CTCATGGTTTATAGCACCTGTCCTCCACTGTCTGACTTGCAGTCATATGTCAGGAAAGTTTTCT
TCATACCTGTTCAGTCTCTCTCATTTGATTTAAGGTCTGTTTCTCATACCTAGTAGGGAGAAGA
GAAGAGACAGTCATCCTCTCTAACACTCTTCAGTCAGCTTCTGGCTTCTCAGTTAACACCAGTT
CATCAGATAAAATTGTTCCACTTCTTTTAGGGTTTTTTTCTTCTCAAATCTATTTTAATTACTT
TATTTATATTTAAAAGCACTAAAATTCTATGTTATATTCAAATTAATTATGCCAGTTAATTTAT
ATCACAATAGTTTGATAGAATTGAGAATAAAGATGTTACCATTGGATTTAATCATCAGACCACC
TGAAAATCAGCACCTAACATTTTTGTATTATCTAACATTTTTCTATTAAAGTATGTTTTATGAT
TTTTATATCTGTACAGATATAACTAGAAAGCCATGCATATATAGTTGTGTATCTTTTTTTCCAT
TAAACGCTAACCTATGTTGCAGTATGATACAAGTATTATATGTTTGGGTATTATGATTGAGCCA
CAACAAATATTACACATTTTTCTTTATCAAATACTTTATTAAACACTAAATGCAAAACTAATTT
TCAAAAGCAGACCCTACAAAAATCAGGTATTCGTGGTTGTTTTATATTTTTGTAGACCACTTTT
GAAATGCTTGTCACTGTTTTTGCAGCATAGACTGGACTAAAACAGTTTTCATTTCAACTCTTAA
ATGATTAAAACTAGGTGTTTGCATAGAAAGGAAATTCTTAAAAATTTATCCCATGGCATATAAA
TTTTGAGAAGCTATACTTTGTGTTAAGATTATGCCCCAAATAAATCTATTGAGTCTTTTTAAAA
TTTTCCATTTTGTTATTACTGATGTTTGTGGTGTTTCTAATGAGCATTGTAAACATACATATTC
ACTTGTAAAATGTAGTTTGCAGCCCACATTAAAATCTGGAGCAGAAAGAATATTTAGAAGTATT
TTTGCTTCATTAGAATGTCTAGTTTGTAAGTGAATTTAAAAAGAAAATTGACTGTACTTGAATT
TACAACTTGACTGTTCTTTCTTTTTAAAATGCTTTTCCCCCATTTAATTAGTATTTTAAGTTCC
AGAAACATCTTCATGGTTTGGAATCACTTTTAGACATAGTATTACTTAAAAACTCAGGGCCCCT
TTCAACTGTTTGTACACTGAAAGAGTTCAGATGCTAACAAACAAGCAATTAGATCTAGTTGAAT
ATTTAAAAGTATTTGTTGCATAGTAATGTTTCATCATATTATTTGACTTAATTCACATCACATG
ATGTTTGATTTCATTAATCATAAAACTTGCCCAGTTCTGTAATTACTGTACAGAAGGAATTACT
CAACTAATTGGCCACATGTTACAGCAGATTTAAGCCTTGGAGTTGAAGCACTGGCTTAAACACT
TTCTGTTCTTGGTTCTGTGGATGTACGTGATGGGGCAAATGTTTCATTCTGTTTTGTTTTTTAA
TATCAAGATTAGGAAAGGTAATTCTGACATGGAATTTCCTCATGGGATAATTAGCATTATAAGA
CTTTCTAAAAGTGAGCAGCTGTCGTTGGTGACAGCTCAATGTCTTTGAGAAGGTGAGCTATGGT
GACCAGCTTTCCACACTGTCAGAGGCAAACAGTTGTTCTTTGAGTTGACAAGCTCAAGTTCTCA
TTGGTCCGCTGTATATTTAAATCTTAGCAGTGAGTTTCTTGTAATCAGTCTCTTGTCTCAGTCT
CCCCGCCTTGTTATCAGTCGTAAGCATATAAAAGAAACATTTGTAAAGATGTATAAGAATAAGA
AAACTAATGACTAAAAAACGCAATTCAAAGCAATTAGGTTTCAATTTAATCTTGAGTTGCTTCA
CTTCTGTGGCTTATTTTTTTTTTCTAGTAACATTTATTTATTTAAGCAGTGTTGTATGCCTTCT
CTTTATTTCCATAGAGATTATTGTATGGGCTTGTGTAAGCTGGAATCATTCTTAATTTTCTGTT
GCTAATTTTTCAGATGACTTTACATGGATAGCTGTAAAATAACTCTTAGGGTGTTATAGCTGAA
ACATTGGCTGGAAGACGTGTAGCTGCCATGCCTTTTCTGAATGGACAGGAGAAACAGAAGCTAC
CAAGTATTCACTTCTGAGGATGCTTTTCCGGAAAAGAAAGGCTGACAATACGGGCACTTCCTCA
GAACCCTCCTTCTTGTTAACGGGTATCTTTCGTTGGTGTGTTTTGCTCTTACATTACAGATAGA
CTATTGTGTGTGAATTTATGAGTAATTACTTTCAGTTATTTTGCTTTTGTATAAGCCATCTGAG
ACCTTGCCATGCTGTATAAGTCGTGTGACGGAGCAGTGTGAGTGTGAGTACAGCAGATCACTCT
CCTTTTGTATTATCTATGGATGCCACTATGAACGCTGACATTAAGCCACTGAAGAGTTTTCTAT
GAATAAGTGTAAGTAAATGCTTTGATATATATAAACCTAAATAAACAGATTGTATTGAGACAGA
GACATTGGCCAAGGAAGTTTGAAGGTGGTTCTTTAGGTTTAAAAGGCTTGCTGTAAAATGGTGC
ATTATTCCACTTATTAAAGATCATATTAATGACAA

hide sequence

RefSeq Acc Id:

XM_006244952 ⟹ XP_006245014

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	61,193,040 - 61,307,280 (+)	NCBI
Rnor_6.0	9	66,568,427 - 66,683,019 (+)	NCBI
Rnor_5.0	9	66,371,542 - 66,486,121 (+)	NCBI

Sequence:

show sequence

CTTCTTGGCTGGCCCAGGGATGACTTCCTCGCTGCAGCGGCCCTTTCGGGTGCCCTGGCTGTTA
TGGGCCGTCCTGCTGGTCAGCACTACGGCTGAACTCTTGAACATCCTCAGCCTCCAACGTGCTG
GAATTACAGCTTCCCAGAATCAAGAACGGCTGTGTGCATTTAAAGACCCGTATCAACAAGACCT
TGGGATTGGTGAGAGTCGAATCTCTCATGAAAATGGGACAATATTATGCTCCAAAGGGAGCACA
TGTTATGGTCTGTGGGAGAAATCAAAAGGGGACATCAATCTTGTGAAACAAGGGTGCTGGTCTC
ACATTGGTGATCCCCAAGAGTGCCACTATGAAGAATGTGTAGTAACTACCACCCCACCCTCAAT
TCAGAATGGAACATACCGTTTTTGCTGCTGTAGTACAGACTTATGTAACGTCAACTTCACTGAG
AACTTCCCACCTCCTGATACAACACCACTCAGTCCGCCTCATTCATCTAATCGGGATGAAACTA
TAATCATTGCTTTGGCATCGGTTTCTGTATTAGCTGTTTTGATAGTCGCCTTATGTTTTGGATA
CAGAATGTTGACAGGAGACAGGAAACAGGGTCTACACAGTGTGAGCATGATGGAGGCGGCAGCG
GCAGAGCCCTCCCTGGACTTGGATAACCTGAAGCTGCTGGAGCTGATTGGACGGGGTCGATATG
GAGCAGTATATAAAGGTTCCTTGGATGAGCGTCCAGTTGCTGTAAAAGTATTTTCTTTTGCAAA
CCGTCAGAATTTTATAAATGAAAAAAACATTTACAGAGTGCCTTTGATGGAACATGACAACATT
GCTCGCTTTATAGTTGGAGACGAGAGGCTCACTGCAGATGGACGCATGGAGTATTTGCTTGTGA
TGGAGTATTATCCCAATGGATCTCTGTGCAAATATCTGAGTCTCCATACAAGTGATTGGGTAAG
CTCTTGCCGTCTGGCTCATTCTGTGACAAGAGGACTGGCTTATCTTCACACAGAATTACCCCGA
GGAGATCATTACAAACCTGCAATTTCCCATCGAGATTTAAACAGCAGAAATGTCCTGGTAAAGA
ATGGTGGCACGTGTGTTATCAGTGACTTTGGTCTGTCCATGAGGCTAACTGGAAACAGGCTGGT
GCGCCCAGGGGAAGAAGATAACGCGGCTATAAGTGAGGTTGGCACAATCCGCTATATGGCACCA
GAAGTGCTAGAAGGAGCTGTGAACCTGAGGGACTGTGAGTCAGCACTGAAGCAAGTGGACATGT
ATGCGCTTGGACTGATCTACTGGGAGGTGTTTATGAGGTGCACAGACCTCTTCCCAGGTGAATC
TGTACCAGATTACCAGATGGCTTTTCAGACAGAAGTTGGAAACCATCCCACATTTGAGGATATG
CAGGTTCTTGTGTCAAGAGAAAAGCAGAGACCCAAGTTCCCAGAAGCCTGGAAAGAAAATAGCC
TGGCAGTGAGGTCACTCAAAGAAACAATCGAAGACTGCTGGGACCAGGATGCAGAGGCTCGGCT
CACTGCACAGTGTGCTGAGGAGAGAATGGCTGAACTCATGATGATATGGGAGAGAAACAAGTCT
GTGAGCCCAACGGTCAACCCAATGTCGACTGCTATGCAGAACGAACGCAACCTATCACATAATA
GGCGTGTGCCAAAAATCGGGCCTTACCCAGATTATTCCTCTTCCTCATATATTGAAGACTCAAT
TCATCACACTGACAGCATTGTGAAAAATATTTCCTCTGAGCATTCAATGTCCAGCACACCGTTG
ACAATAGGAGAAAAGAACCGAAACTCAATTAATTATGAACGACAGCAAGCACAAGCTCGAATCC
CTAGCCCAGAAACAAGCGTCACAAGCCTGTCCACAAACACAACCACCACAAACACCTCTGGCCT
CACTCCAAGTACTGGCATGACCACGATATCTGAGATGCCATACCCAGATGAGACACATTTGCAT
GCCACAAATGTTGCACAGTCACTCGGGCCAACCCCTGTCTGCTTACAGCTGACAGAAGAAGACT
TGGAAACTAATAAGCTAGACCCAAAAGAAGTTGATAAGAACCTCAAGGAAAGCTCTGATGAGAA
TCTCATGGAGCATTCTCTGAAGCAGTTCAGTGGGCCAGACCCGTTGAGCAGTACCAGTTCCAGC
TTGCTTTATCCACTCATAAAGCTTGCGGTGGAAGTGACTGGACAACAGGACTTCACACAGGCTG
CAAATGGGCAAGCATGTTTAATTCCTGATGTCCCACCTGCTCAGCTCTATCCTCTCCCTAAGCA
ACAGAACCTTCCGAAGAGACCTACTAGTTTGCCTTTGAACACCAAAAATTCAACTAAAGAACCC
CGGCTAAAATTTGGCAACAAGCACAAATCAAACTTGAAACAAGTAGAAACTGGAGTTGCCAAGA
TGAATACAATCAATGCAGCAGAGCCTCATGTGGTGACAGTAACTATGAATGGTGTGGCAGGTAG
AAGCCACAATGTTAATTCCCATGCTGCCACAACCCAGTATGCCAATGGGGTAGTGCCATCTGGC
CAGGCAGCCAACATAGTGGCACATAGGGCCCAAGAAATGCTGCAGAATCAATTTAATGGTGAGG
ATACCAGACTGAATATCAATTCCAGTCCTGATGAACATGAACCTTTACTGAGACGAGAGCAGCA
GGCTGGCCATGATGAAGGGGTTCTGGATCGTTTGGTAGACAGGAGGGAACGGCCATTAGAAGGT
GGCCGAACTAATTCCAATAACAACAACAGCAATCCATGTTCAGAACAAGATGTCCCTACACAAG
GTGTTACAAGCACAGCTGCAGACCCTGGGCCAGCAAAGCCCAGAAGAGCACAGAGGCCCAATTC
TCTGGATCTTTCAGCCACAAATATCCTGGATGGCAGCAGCATGCAGAGTGAGTCAACGCAGGAT
GGCAAATCAGGATCAGGCGAAAAGATCAAGAGACGTGTGAAAACTCCATACTCTCTTAAGCGGT
GGCGCCCATCCACCTGGGTCATCTCCACCGAGCCACTGGACTGTGAGGTCAACAACAATGGCAG
TGACAGGGCAGTCCATTCTAAATCTAGCACTGCTGTGTACCTCGCAGAGGGAGGCACTGCCACA
ACCATGGTGTCTAAAGATATAGGAATGAATTGTCTGTGAGATGTTTTCAAGCTTATGGAGTGAA
ATTATTTTTTTGCATCATTTAAACATGCAGAAGACATTTTAAAAAAAAAAAAACTGCTTTAACC
TCCTGTCAGCACCCCTTCCCACCCCTGGAGCAAGGACTTGCTTTAAATAGATTTCAGCTATGCA
GAAAACTTTAGCTTATGCTTCCATATTTTTTAATTTTGTTTTTTAAGTTTTGCACTTTTGTTTA
GTCTTGCTAAAGTTCTATTTGTCTGTTATGACCACATTATATGTGTGCTTATCAAAAGTGGTCT
CAAAATATTTTTTTTAAGAAAAAAAGCAAAAACAATGTATTGCTGATAATCAGTTTGGACCATT
TTCTAAAGGTCATTAAAACAGAAGCAAATTAAGACAGGTTTGACTGCAACGGTGTCTGGTATCC
ATGTTTTATTTCTGGGCACAAGCTAGTTTATATGTTAACGTGTTTTTGACCATAATCTGTTGGA
CATTCTTCTGTGTTTTATTTGAATGTGCAATAGTCTGTAGACCACAAAGAAGCTTTCTCATCTG
CTCTCTTCCTAGCAGGGCACACATTCTTCTTCCATTGTTGAAAGAAACATTTTCCCTGGTCTTC
GACAATATGAACATTTTCCAGCTTTCTCCTTATGGAGATGCTTAGACGCTGTCCAAAGGGCTCC
ACACAGGACTTACCAAAACATGTATTGAGATGCCATTGTCTTCTAACCTTCCAGTGCTAAGTGT
TTCCTTCCAGGCATTTCACTAAGCATGTCTGGTTCTGGTTTTGGAAGCTCATAAGAGAGCATAG
AACAAAACAGAGGAAAGCAAATATTAGCCTTCTCCCTTTTATTTTTCTATGTTTATGTTCATGT
CTGTATTCATTATTTAAGAAGTATTTTTTATCAAAAAATGTATAGAGCTAAACCTACATGGAAT
GTTTAAATAGCTGGGCAAAGTGATTAGTATAGTAACTTTCACTTTCTGACCGTCACAAATTAAA
TCACATTTCCTATTTATAGTAACTTCAGGAGTAATCGAATCTATAGGATGGTTCCTTGTTTCCC
AGCACTGCCTGACAGTTCTATGTGAAAAAGTGATTCCTCCTCCTCCCGTGACCTAAAACACTGT
GGAAAGCTCCAGCCAGCTCGCCAGATCCTATGGAAGAAAGGCTTGCTGCCAACTTAGGGCCGTT
GAGCAGACTAAGATTGGCCCTGTCTTTCCTAACTTCGTTCTTCACTGACTGCTTTTGTAGTTTC
TCCCTTTGCCAGTTTCACACGTTCTCTGATGGCGAGCAGCACTCACTGTTTGTCGTGATAGAGC
GTCTTCTGCTGACGATGTGCCGTGGCCTTGCTGTCACGATGCTTTTGCTTCTTTTGTCACTAGT
GATCTCTGAAACAACAGTCTCTGTGTCTTTTAATAAAGCACTTTCTGTCAAAAATTTTAGAAAA
TTTCCCTAAACATTGCTTCCTATCAGTTTGTAGACACTGTTCTCATGGTTTTCAGATTCTCAGA
ATCCTTAATATCCATTATCTGACTATGTTTTCAGTTTTAGCAGGAAGATAAAAAGTTAAGTGCA
AATCTCCAAAGTCCTGATTTTGGTTCTTCTGTCCTGAACCATTTTAATCCATTCTCATTTGTAA
TCCTCTTTCCTTCCGTTTAACTCGTACCCGACCTGCCGTGCTTTGACGTGACAGCGTTTTCCAT
GTAGTCAGCCGCAGCACTGACGAGAGCTCTCAGTTCTTAGGATTAGGATTGTCTTACCTGTGCC
CAGGACTCCTTTCTGACTTTTGTGTTTCATCGGCCCCTCTTGTGGTTCAGAGTCTTATATATAT
TTTTGTCTTCTCCATACAGTTGTTTTTGTTTTTGTTTTTTCTCTAGTTAGTTACTGCCCTTTGT
CTATGTAACAAATAATTTGAATCTTTCACTCATTTCTTTTGTCCAAATGGCTTTCAAATGCATT
TCAGAATTTTTATTTTCCAATTGTATGACAACTTTAAATCATAATAAATTATATTCCTCCCATC
TTCAATTTGAAACATTAAGAATAAATGACCCTTTGAGGTCCAACTGATCTTTTCCTATCAGAAA
AATTGTCTTACATTCTGATACAGTGTATATTAGGGCCAGTCAGTTTGAATTTTTCAAGTCTTTA
ATGTTTAATAATAGAATGCTTCAAAAATTAATATGCCAGATAAAAGAAATCTCTATAGTTCCCA
TCTCATGCAAATGTATTTAAAACAAATAATTCCTTGAACTGCTTGAAGAATAGGAAAGGTAGTA
AGTATAGGTCATTTTAATAAAATTTGAAATCTGTACTACACAGCATGCAGAAATCCCTTTAACA
CTAGTTAGATTTATTTAATCTGATTCTTGAGCCGAAATGGAATTTACCACAAAATTTCACACAC
AGAAATTAATTTTAGGCCTTTTGAATGAAAGTCATTTAATTTAAAAAGATTTCTAGGGACAGTA
ATATAATAGGACATCAGAGTATGGTTAGTTCCCTTAAGAATATTCTAGTTGTGGGGCTGGAGGG
ATGACATAATAATAACAGTGCTTCCTGCGCTTACAGAGGACCCAAGTTCAGTTCCCAGCAGCTA
CATGGCAGCTCACAACTTCCACAGAATCCAATTCCCTCTTTTGGCCTCCACTGACATGCACATA
ACACCATCCTACCCGCACACACACACACATGCACATAATTATAAATGACAACAGTAAACCTTAA
AATACTAGTTATATACCAGAGCTATGTGATGGAAATAACTTGATTTGAATTATGTATAGAGTAA
AATCATTTAAATAAAAATCCTAGCTAATTTAAATGTATAATTTAAAAAATACTGCTACTGTAGA
AGTTTGTGAAGACATGCTGAAAACTGGCATTACATACACTCATCTTTTCATTCTCAGAGCAACC
ATTATTATAATTAATATTCATATTTTACAAATGAGGAAATAAAAATTAAATGGAAATCTGTCTG
TTTCATCCCAGACATACCTGGGATTTCACCCTGGGTCTGTCTCTCCATGTGTCTTTTATGCACA
ACACATGGTCTACATTCTTTATGAGCTGATGTGCAGTGTCCTGACATGTTGTGCTCCAGCAGAC
GTGTGGTTTGTGTGTAAGCCAGGCCAGGTTCCTTAATGATCTTAAGTTAGGTAAAGCTAAAACA
GTTCCTAATTCAATACAAAATTCAGCCCACATCTCAACAGTCGTCTTACCTGTCTCCTAATATT
TTTACATTGCAGAAGAAAAGGGAAAGTAAATGCTAGGAGACAGTGAAGGGAGCAGATGGAGCGG
GAGCTCCCTAACGTGACCCCGTACCTCTCTCGGAAAGAAGACTTTTATGTAAACTTGCAGTCTT
CTCAATCCTTTGACTCCATCTTTAAAGCTTCAGTTTTACCAATGTTAGGAAAAAGTTGTTAATC
CAGAGAACTAAATAATCTGTAGAGAGAGTAGAAGGTTAACATTCGCAGGCTTGTGGAGCTTCTG
GATGTGTGTATACTTTTTCCAGAACCTGTATGTTGGTTCTGAATATAAGGAACACTCAAATCAG
TGGGAATTACAAATTTTATTTAAAATATTTCCAAGTTTGACTTCTGAATCCCAAAGGAAAATCT
GATATGGTACAGCTAACCTGTTTACTCTCTGTTAATTAGTCATTTAAAGTGGAAAGAAAATAAA
CATTGGTTTCCTCTTGTCATGTTTATGGACATAAATATTTCACTGGGAGTCACTATTAGAATTT
GATATTATATTTATCACATTTTATAAACCTATGTTGAGCTTAGTACCAGTCATGTATATGTTAT
TATATGATTAGCCACAGGTTTTTGAAAATATATAATTACCTTATATCCTTAAGTCCTTAAAAGA
TTCTGCACACATTCTAATTCTACTGTTCTAGACCAGCATTCTAGGATGTGTGTAACAACCCCTT
ATAGGCCCTAGGAGCCTTTTAGGCTATAATAGTTTTAAATATTCACACCCTTGACTAGCAGTGG
GTTGTGGTGTATTTTGCTTTTCTTTTTAAGTTTTTTTTAGATTATGAACTATGCAAACTTCATC
CAAAAACTACCTTTCATGATCCCTTCCTAACTGCTTTTTGATTCTTTCAGTCTAGCCAGCTACT
TTCTGAACTACTTAACAAAGGTTATTATCAAAAAAGACTTTTCTATAAGTGTCCACATTAACAC
TGAGGAAATCTCCATGTGCCCAAAGAGGTGGTAACACCTACCTGTTCCTCTCTTTAAGTCCCTC
ATGGTTTATAGCACCTGTCCTCCACTGTCTGACTTGCAGTCATATGTCAGGAAAGTTTTCTTCA
TACCTGTTCAGTCTCTCTCATTTGATTTAAGGTCTGTTTCTCATACCTAGTAGGGAGAAGAGAA
GAGACAGTCATCCTCTCTAACACTCTTCAGTCAGCTTCTGGCTTCTCAGTTAACACCAGTTCAT
CAGATAAAATTGTTCCACTTCTTTTAGGGTTTTTTTCTTCTCAAATCTATTTTAATTACTTTAT
TTATATTTAAAAGCACTAAAATTCTATGTTATATTCAAATTAATTATGCCAGTTAATTTATATC
ACAATAGTTTGATAGAATTGAGAATAAAGATGTTACCATTGGATTTAATCATCAGACCACCTGA
AAATCAGCACCTAACATTTTTGTATTATCTAACATTTTTCTATTAAAGTATGTTTTATGATTTT
TATATCTGTACAGATATAACTAGAAAGCCATGCATATATAGTTGTGTATCTTTTTTTCCATTAA
ACGCTAACCTATGTTGCAGTATGATACAAGTATTATATGTTTGGGTATTATGATTGAGCCACAA
CAAATATTACACATTTTTCTTTATCAAATACTTTATTAAACACTAAATGCAAAACTAATTTTCA
AAAGCAGACCCTACAAAAATCAGGTATTCGTGGTTGTTTTATATTTTTGTAGACCACTTTTGAA
ATGCTTGTCACTGTTTTTGCAGCATAGACTGGACTAAAACAGTTTTCATTTCAACTCTTAAATG
ATTAAAACTAGGTGTTTGCATAGAAAGGAAATTCTTAAAAATTTATCCCATGGCATATAAATTT
TGAGAAGCTATACTTTGTGTTAAGATTATGCCCCAAATAAATCTATTGAGTCTTTTTAAAATTT
TCCATTTTGTTATTACTGATGTTTGTGGTGTTTCTAATGAGCATTGTAAACATACATATTCACT
TGTAAAATGTAGTTTGCAGCCCACATTAAAATCTGGAGCAGAAAGAATATTTAGAAGTATTTTT
GCTTCATTAGAATGTCTAGTTTGTAAGTGAATTTAAAAAGAAAATTGACTGTACTTGAATTTAC
AACTTGACTGTTCTTTCTTTTTAAAATGCTTTTCCCCCATTTAATTAGTATTTTAAGTTCCAGA
AACATCTTCATGGTTTGGAATCACTTTTAGACATAGTATTACTTAAAAACTCAGGGCCCCTTTC
AACTGTTTGTACACTGAAAGAGTTCAGATGCTAACAAACAAGCAATTAGATCTAGTTGAATATT
TAAAAGTATTTGTTGCATAGTAATGTTTCATCATATTATTTGACTTAATTCACATCACATGATG
TTTGATTTCATTAATCATAAAACTTGCCCAGTTCTGTAATTACTGTACAGAAGGAATTACTCAA
CTAATTGGCCACATGTTACAGCAGATTTAAGCCTTGGAGTTGAAGCACTGGCTTAAACACTTTC
TGTTCTTGGTTCTGTGGATGTACGTGATGGGGCAAATGTTTCATTCTGTTTTGTTTTTTAATAT
CAAGATTAGGAAAGGTAATTCTGACATGGAATTTCCTCATGGGATAATTAGCATTATAAGACTT
TCTAAAAGTGAGCAGCTGTCGTTGGTGACAGCTCAATGTCTTTGAGAAGGTGAGCTATGGTGAC
CAGCTTTCCACACTGTCAGAGGCAAACAGTTGTTCTTTGAGTTGACAAGCTCAAGTTCTCATTG
GTCCGCTGTATATTTAAATCTTAGCAGTGAGTTTCTTGTAATCAGTCTCTTGTCTCAGTCTCCC
CGCCTTGTTATCAGTCGTAAGCATATAAAAGAAACATTTGTAAAGATGTATAAGAATAAGAAAA
CTAATGACTAAAAAACGCAATTCAAAGCAATTAGGTTTCAATTTAATCTTGAGTTGCTTCACTT
CTGTGGCTTATTTTTTTTTTCTAGTAACATTTATTTATTTAAGCAGTGTTGTATGCCTTCTCTT
TATTTCCATAGAGATTATTGTATGGGCTTGTGTAAGCTGGAATCATTCTTAATTTTCTGTTGCT
AATTTTTCAGATGACTTTACATGGATAGCTGTAAAATAACTCTTAGGGTGTTATAGCTGAAACA
TTGGCTGGAAGACGTGTAGCTGCCATGCCTTTTCTGAATGGACAGGAGAAACAGAAGCTACCAA
GTATTCACTTCTGAGGATGCTTTTCCGGAAAAGAAAGGCTGACAATACGGGCACTTCCTCAGAA
CCCTCCTTCTTGTTAACGGGTATCTTTCGTTGGTGTGTTTTGCTCTTACATTACAGATAGACTA
TTGTGTGTGAATTTATGAGTAATTACTTTCAGTTATTTTGCTTTTGTATAAGCCATCTGAGACC
TTGCCATGCTGTATAAGTCGTGTGACGGAGCAGTGTGAGTGTGAGTACAGCAGATCACTCTCCT
TTTGTATTATCTATGGATGCCACTATGAACGCTGACATTAAGCCACTGAAGAGTTTTCTATGAA
TAAGTGTAAGTAAATGCTTTGATATATATAAACCTAAATAAACAGATTGTATTGAGACAGAGAC
ATTGGCCAAGGAAGTTTGAAGGTGGTTCTTTAGGTTTAAAAGGCTTGCTGTAAAATGGTGCATT
ATTCCACTTATTAAAGATCATATTAATGACAA

hide sequence

RefSeq Acc Id:

XM_039082970 ⟹ XP_038938898

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	61,243,173 - 61,307,280 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_536332	(Get FASTA)	NCBI Sequence Viewer
	XP_006245013	(Get FASTA)	NCBI Sequence Viewer
	XP_006245014	(Get FASTA)	NCBI Sequence Viewer
	XP_038938898	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAB71720	(Get FASTA)	NCBI Sequence Viewer
	EDL98946	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_536332 ⟸ NM_080407
- Peptide Label:	precursor
- UniProtKB:	F1LQC5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTSSLQRPFRVPWLLWAVLLVSTTAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGS TCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFT ENFPPPDTTPLSPPHSSNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSVSMMEAA AAEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDN IARFIVGDERLTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELP RGDHYKPAISHRDLNSRNVLVKNGGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMA PEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRCTDLFPGESVPDYQMAFQTEVGNHPTFED MQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNK SVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTP LTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTSGLTPSTGMTTISEMPYPDETHL HATNVAQSLGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSS SLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQLYPLPKQQNLPKRPTSLPLNTKNSTKE PRLKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNSHAATTQYANGVVPS GQAANIVAHRAQEMLQNQFNGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLE GGRTNSNNNNSNPCSEQDVPTQGVTSTAADPGPAKPRRAQRPNSLDLSATNILDGSSMQIGEST QDGKSGSGEKIKRRVKTPYSLKRWRPSTWVISTEPLDCEVNNNGSDRAVHSKSSTAVYLAEGGT ATTMVSKDIGMNCL hide sequence

RefSeq Acc Id:

XP_006245013 ⟸ XM_006244951

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTSSLQRPFRVPWLLWAVLLVSTTAELLNILSLQRAGITASQNQERLCAFKDPYQQDLGIGESR
ISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYR
FCCCSTDLCNVNFTENFPPPDTTPLSPPHSSNRDETIIIALASVSVLAVLIVALCFGYRMLTGD
RKQGLHSVSMMEAAAAEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFIN
EKNIYRVPLMEHDNIARFIVGDERLTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAH
SVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNGGTCVISDFGLSMRLTGNRLVRPGEED
NAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRCTDLFPGESVPDYQM
AFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAE
ERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSI
VKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTSGLTPSTGM
TTISEMPYPDETHLHATNVAQSLGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSL
KQFSGPDPLSSTSSSLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQLYPLPKQQNLPKR
PTSLPLNTKNSTKEPRLKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNS
HAATTQYANGVVPSGQAANIVAHRAQEMLQNQFNGEDTRLNINSSPDEHEPLLRREQQAGHDEG
VLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDVPTQGVTSTAADPGPAKPRRAQRPNSLDLSAT
NILDGSSMQIGESTQDGKSGSGEKIKRRVKTPYSLKRWRPSTWVISTEPLDCEVNNNGSDRAVH
SKSSTAVYLAEGGTATTMVSKDIGMNCL

hide sequence

RefSeq Acc Id:

XP_006245014 ⟸ XM_006244952

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTSSLQRPFRVPWLLWAVLLVSTTAELLNILSLQRAGITASQNQERLCAFKDPYQQDLGIGESR
ISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYR
FCCCSTDLCNVNFTENFPPPDTTPLSPPHSSNRDETIIIALASVSVLAVLIVALCFGYRMLTGD
RKQGLHSVSMMEAAAAEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFIN
EKNIYRVPLMEHDNIARFIVGDERLTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAH
SVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNGGTCVISDFGLSMRLTGNRLVRPGEED
NAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRCTDLFPGESVPDYQM
AFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAE
ERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSI
VKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTSGLTPSTGM
TTISEMPYPDETHLHATNVAQSLGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSL
KQFSGPDPLSSTSSSLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQLYPLPKQQNLPKR
PTSLPLNTKNSTKEPRLKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNS
HAATTQYANGVVPSGQAANIVAHRAQEMLQNQFNGEDTRLNINSSPDEHEPLLRREQQAGHDEG
VLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDVPTQGVTSTAADPGPAKPRRAQRPNSLDLSAT
NILDGSSMQSESTQDGKSGSGEKIKRRVKTPYSLKRWRPSTWVISTEPLDCEVNNNGSDRAVHS
KSSTAVYLAEGGTATTMVSKDIGMNCL

hide sequence

RefSeq Acc Id:

ENSRNOP00000037011 ⟸ ENSRNOT00000035238

RefSeq Acc Id:	XP_038938898 ⟸ XM_039082970
- Peptide Label:	isoform X3

Protein Domains

Protein kinase

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:71082	AgrOrtholog
Ensembl Genes	ENSRNOG00000022196	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000037011	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000035238	ENTREZGENE, UniProtKB/TrEMBL
InterPro	Activin_rcpt	UniProtKB/TrEMBL
	BMPR2	UniProtKB/TrEMBL
	Kinase-like_dom	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	TGFB_receptor	UniProtKB/TrEMBL
KEGG Report	rno:140590	UniProtKB/TrEMBL
NCBI Gene	140590	ENTREZGENE
PANTHER	PTHR23255	UniProtKB/TrEMBL
	PTHR23255:SF97	UniProtKB/TrEMBL
Pfam	Activin_recp	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PhenoGen	Bmpr2	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	F1LQC5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-04	Bmpr2	bone morphogenetic protein receptor type 2	Bmpr2	bone morphogenetic protein receptor type II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-09	Bmpr2	bone morphogenetic protein receptor type II	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-26	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-07-09	Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)