Izumo1 (izumo sperm-oocyte fusion 1) - Rat Genome Database

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Gene: Izumo1 (izumo sperm-oocyte fusion 1) Rattus norvegicus
Analyze
Symbol: Izumo1
Name: izumo sperm-oocyte fusion 1 (Ensembl:izumo sperm-egg fusion 1)
RGD ID: 1565454
Description: Enables protein homodimerization activity. Involved in binding activity of sperm to zona pellucida. Located in plasma membrane. Orthologous to human IZUMO1 (izumo sperm-oocyte fusion 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: izumo sperm-egg fusion 1; izumo sperm-egg fusion protein 1; LOC499152; OBF; oocyte binding/fusion factor; similar to hypothetical protein MGC34799; sperm-specific protein izumo
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Izumo1em1Osb  
Genetic Models: W;WIAR-Izumo1em1Osb
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,227,603 - 105,233,357 (+)NCBIGRCr8
mRatBN7.2196,090,817 - 96,096,893 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1101,476,573 - 101,482,331 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,949,270 - 109,955,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,239,647 - 103,245,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,603,222 - 101,608,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,603,222 - 101,608,976 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,682,002 - 102,687,757 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,090,118 - 96,095,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera190,344,795 - 90,350,549 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm. Ellerman DA, etal., Mol Reprod Dev. 2009 Dec;76(12):1188-99. doi: 10.1002/mrd.21092.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Participation of WD repeat-containing protein 54 (WDR54) in rat sperm-oocyte fusion through interaction with both IZUMO1 and JUNO. Lai X, etal., Theriogenology. 2024 Jan 15;214:286-297. doi: 10.1016/j.theriogenology.2023.10.031. Epub 2023 Nov 7.
4. Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats. Matsumura T, etal., Front Cell Dev Biol. 2022 Jan 12;9:810118. doi: 10.3389/fcell.2021.810118. eCollection 2021.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:15759005   PMID:19144954   PMID:20375058   PMID:20421979   PMID:22954305   PMID:24739963   PMID:27309808   PMID:27624483  


Genomics

Comparative Map Data
Izumo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,227,603 - 105,233,357 (+)NCBIGRCr8
mRatBN7.2196,090,817 - 96,096,893 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1101,476,573 - 101,482,331 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,949,270 - 109,955,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,239,647 - 103,245,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,603,222 - 101,608,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,603,222 - 101,608,976 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,682,002 - 102,687,757 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,090,118 - 96,095,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera190,344,795 - 90,350,549 (+)NCBICelera
Cytogenetic Map1q22NCBI
IZUMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,740,852 - 48,746,909 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,740,852 - 48,746,909 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,244,109 - 49,250,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,935,957 - 53,941,978 (-)NCBINCBI36Build 36hg18NCBI36
Celera1946,110,237 - 46,116,258 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,622,956 - 45,628,979 (-)NCBIHuRef
CHM1_11949,245,907 - 49,251,937 (-)NCBICHM1_1
T2T-CHM13v2.01951,735,271 - 51,741,330 (-)NCBIT2T-CHM13v2.0
Izumo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,270,251 - 45,276,653 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,271,235 - 45,278,247 (+)EnsemblGRCm39 Ensembl
GRCm38745,621,811 - 45,627,242 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,621,811 - 45,628,823 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,877,181 - 52,882,612 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,489,853 - 45,495,284 (+)NCBIMGSCv36mm8
Celera741,083,355 - 41,088,784 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.39NCBI
Izumo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555591,825,589 - 1,830,535 (+)NCBIChiLan1.0ChiLan1.0
IZUMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,844,051 - 54,850,311 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,770,395 - 56,776,681 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,740,372 - 45,747,177 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,330,542 - 54,337,974 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,330,545 - 54,337,533 (-)Ensemblpanpan1.1panPan2
IZUMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,579,073 - 107,583,163 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,101,516 - 107,105,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,103,745 - 108,107,828 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11107,770,586 - 107,774,666 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,417,509 - 107,421,583 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,253,081 - 108,257,163 (+)NCBIUU_Cfam_GSD_1.0
IZUMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,072,265 - 54,076,474 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,072,607 - 54,076,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,819,983 - 49,824,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IZUMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607321,860,467 - 21,867,228 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Izumo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,173,070 - 5,176,480 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,171,778 - 5,176,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Izumo1
17 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:126
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000033278
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat


Genetic Models
This gene Izumo1 is modified in the following models/strains:
W;WIAR-Izumo1em1Osb    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 39 113 79 78 47 25 47 6 188 87 93 37 59 31

Sequence


Ensembl Acc Id: ENSRNOT00000033278   ⟹   ENSRNOP00000035119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1101,603,222 - 101,608,976 (+)Ensembl
RefSeq Acc Id: NM_001017514   ⟹   NP_001017514
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,227,603 - 105,233,357 (+)NCBI
mRatBN7.2196,091,138 - 96,096,893 (+)NCBI
Rnor_6.01101,603,222 - 101,608,977 (+)NCBI
Rnor_5.01102,682,002 - 102,687,757 (+)NCBI
RGSC_v3.4196,090,118 - 96,095,872 (+)RGD
Celera190,344,795 - 90,350,549 (+)RGD
Sequence:
RefSeq Acc Id: XM_039087498   ⟹   XP_038943426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,230,300 - 105,233,357 (+)NCBI
mRatBN7.2196,093,836 - 96,096,893 (+)NCBI
RefSeq Acc Id: XM_039087504   ⟹   XP_038943432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,228,596 - 105,232,038 (+)NCBI
mRatBN7.2196,090,817 - 96,095,521 (+)NCBI
RefSeq Acc Id: NP_001017514   ⟸   NM_001017514
- Peptide Label: precursor
- UniProtKB: Q6AY06 (UniProtKB/Swiss-Prot),   A6JB60 (UniProtKB/TrEMBL),   A0A455R7F4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035119   ⟸   ENSRNOT00000033278
RefSeq Acc Id: XP_038943432   ⟸   XM_039087504
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038943426   ⟸   XM_039087498
- Peptide Label: isoform X1
Protein Domains
Ig-like C2-type   Izumo protein immunoglobulin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY06-F1-model_v2 AlphaFold Q6AY06 1-383 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690048
Promoter ID:EPDNEW_R572
Type:initiation region
Name:Izumo1_1
Description:izumo sperm-egg fusion 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,603,170 - 101,603,230EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565454 AgrOrtholog
BioCyc Gene G2FUF-59664 BioCyc
Ensembl Genes ENSRNOG00000024678 Ensembl
  ENSRNOG00055006637 UniProtKB/Swiss-Prot
  ENSRNOG00060010419 UniProtKB/Swiss-Prot
  ENSRNOG00065031178 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00055010805 UniProtKB/Swiss-Prot
  ENSRNOT00060017622 UniProtKB/Swiss-Prot
  ENSRNOT00065053759 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132791 IMAGE-MGC_LOAD
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  IZUMO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Izumo-Ig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IZUMO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:499152 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94329 IMAGE-MGC_LOAD
NCBI Gene 499152 ENTREZGENE
PANTHER IZUMO SPERM-EGG FUSION PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR35540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IZUMO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Izumo-Ig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Izumo1 PhenoGen
RatGTEx ENSRNOG00000024678 RatGTEx
  ENSRNOG00055006637 RatGTEx
  ENSRNOG00060010419 RatGTEx
  ENSRNOG00065031178 RatGTEx
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A455R7F4 ENTREZGENE, UniProtKB/TrEMBL
  A6JB60 ENTREZGENE, UniProtKB/TrEMBL
  IZUM1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-03 Izumo1  izumo sperm-oocyte fusion 1  Izumo1  izumo sperm-egg fusion 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Izumo1  izumo sperm-egg fusion 1  LOC499152  similar to hypothetical protein MGC34799  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC499152  similar to hypothetical protein MGC34799      Symbol and Name status set to provisional 70820 PROVISIONAL