Gene: Agtr1a (angiotensin II receptor, type 1a) Rattus norvegicus
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Description: ENCODES a protein that exhibits angiotensin type I receptor activity; D1 dopamine receptor binding; G-protein alpha-subunit binding; INVOLVED IN activation of Janus kinase activity; aging; angiotensin-activated signaling pathway; PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; angiotensin III signaling pathway via AT1 receptor; G protein mediated signaling pathway via Galpha12/Galpha13 family; ASSOCIATED WITH anti-basement membrane glomerulonephritis; asthma; Cardiomegaly; FOUND IN basolateral plasma membrane; cytoplasmic vesicle; dendrite; INTERACTS WITH (R)-lipoic acid; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate
Type: protein-coding
Also known as: Agtr1; Angiotensin II receptor type 1 (AT1A); angiotensin II receptor, type 1; Angiotensin II receptor, type 1 (AT1A); angiotensin II type-1A receptor; angiotensin receptor 1a; AT1; AT1A; AT1R; type-1A angiotensin II receptor; vascular type-1 angiotensin II receptor
Homo sapiens (human) : AGTR1 (angiotensin II receptor type 1)  HGNC  Alliance
Mus musculus (house mouse) : Agtr1a (angiotensin II receptor, type 1a)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agtr1 (angiotensin II receptor type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AGTR1 (angiotensin II receptor type 1)
Canis lupus familiaris (dog) : AGTR1 (angiotensin II receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agtr1 (angiotensin II receptor type 1)
more info ...
Allele / Splice: Agtr1aem5Mcwi   Agtr1aem1Mcwi  
Genetic Models: SS-Agtr1aem1Mcwi SS-Agtr1aem5Mcwi
Is Marker For: QTLs:   Bp343  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01735,907,102 - 35,958,136 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01737,217,810 - 37,270,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41740,629,318 - 40,684,982 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11740,632,160 - 40,687,823 (-)NCBI
Celera1733,705,975 - 33,757,157 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Protein Structures

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Agtr1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2070
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-07-10
Status: ACTIVE