Gene: Sptlc3 (serine palmitoyltransferase, long chain base subunit 3) Rattus norvegicus
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Symbol: Sptlc3
Name: serine palmitoyltransferase, long chain base subunit 3
Description: ENCODES a protein that exhibits serine C-palmitoyltransferase activity (ortholog); INVOLVED IN sphingoid biosynthetic process (ortholog); PARTICIPATES IN sphingolipid metabolic pathway; ASSOCIATED WITH neuropathy (ortholog); peripheral nervous system disease (ortholog); sensory peripheral neuropathy (ortholog); FOUND IN serine C-palmitoyltransferase complex (ortholog); INTERACTS WITH acrylamide; bisphenol A; testosterone
AGR Description: Predicted to have serine C-palmitoyltransferase activity; predicted to be involved in sphingoid biosynthetic process; predicted to localize to the serine C-palmitoyltransferase complex; orthologous to human SPTLC3 (serine palmitoyltransferase long chain base subunit 3).
Merged Description: Predicted to have serine C-palmitoyltransferase activity; predicted to be involved in sphingoid biosynthetic process; predicted to localize to the serine C-palmitoyltransferase complex; orthologous to human SPTLC3 (serine palmitoyltransferase long chain base subunit 3); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH acrylamide; bisphenol A; testosterone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC296188; RGD1310030; serine palmitoyltransferase 3; similar to dJ718P11.1.1 (novel class II aminotransferase similar to serine palmotyltransferase (isoform 1)); similar to RIKEN cDNA C130053K05 gene
Orthologs:
Homo sapiens (human) : SPTLC3 (serine palmitoyltransferase long chain base subunit 3)  HGNC  Alliance
Mus musculus (house mouse) : Sptlc3 (serine palmitoyltransferase, long chain base subunit 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sptlc3 (serine palmitoyltransferase long chain base subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SPTLC3 (serine palmitoyltransferase long chain base subunit 3)
Canis lupus familiaris (dog) : SPTLC3 (serine palmitoyltransferase long chain base subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sptlc3 (serine palmitoyltransferase long chain base subunit 3)
Sus scrofa (pig) : SPTLC3 (serine palmitoyltransferase long chain base subunit 3)
more info ...
Allele / Splice: Sptlc3Tn(sb-T2/Bart3)2.147Mcwi  
Genetic Models: F344-Sptlc3Tn(sb-T2/Bart3)2.147Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03132,560,437 - 132,689,313 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03139,023,075 - 139,151,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43127,691,668 - 127,825,206 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13127,597,526 - 127,729,920 (+)NCBI
Celera3125,501,233 - 125,630,510 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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QTLs in Region (Rnor_6.0)
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Sequence

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Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
  
More on Sptlc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310030
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.