Gene: Erbb4 (erb-b2 receptor tyrosine kinase 4) Rattus norvegicus
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Symbol: Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Description: ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); protein homodimerization activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN mammary gland development; negative regulation of muscle cell apoptotic process; odontogenesis; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; calcium/calcium-mediated signaling pathway; endocytosis pathway; ASSOCIATED WITH congestive heart failure; Diabetic Cardiomyopathies; median neuropathy; FOUND IN caveola; cytoplasm; membrane raft; INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-erbB-4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene 4
Orthologs:
Homo sapiens (human) : ERBB4 (erb-b2 receptor tyrosine kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Erbb4 (erb-b2 receptor tyrosine kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erbb4 (erb-b2 receptor tyrosine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ERBB4 (erb-b2 receptor tyrosine kinase 4)
Canis lupus familiaris (dog) : ERBB4 (erb-b2 receptor tyrosine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erbb4 (erb-b2 receptor tyrosine kinase 4)
more info ...
Allele / Splice: Erbb4Tn(sb-T2/Bart3)2.208Mcwi  
Genetic Models: F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0975,021,790 - 76,178,936 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0974,804,287 - 75,310,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4966,843,898 - 67,967,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1966,990,879 - 68,114,952 (-)NCBI
Celera967,006,553 - 68,064,842 (-)NCBICelera
Cytogenetic Map9q32-q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Genomics

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QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Erbb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620486
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE



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