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Strain Registration

Strain: SS-Nox4em2Ncf2em1Mcwi

Symbol: SS-Nox4em2Ncf2em1Mcwi
Strain: SS-Nox4em2Ncf2em1
Substrain: Mcwi
RGD ID: 13506176
Citation ID: RRID:RGD_13506176
Ontology ID: RS:0004578
Alleles: Ncf2em1Mcwi;   Nox4em2Mcwi
Previously known as: SS-Nox4em2Ncf2em1Mcwi; SS-Nox4em2/Ncf2em1Mcwi
Type: mutant
Source: MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origin: Breeding together of SS-Nox4em2Mcwi (RGDID: 4139883) and SS-Ncf2em1Mcwi (RGDID: 5144104), both models were generated by ZFN mutagenesis.
Genetic Status: Homozygous
Last Known Status: Cryopreserved Sperm; Cryorecovery (as of 2018-11-12)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21364,958,217 - 64,958,221RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01370,229,196 - 70,229,200RGD_MAPPER_PIPELINERnor6.0
Rnor_6.01150,861,996 - 150,862,003RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01375,200,283 - 75,200,287RGD_MAPPER_PIPELINERnor5.0
Rnor_5.01375,200,283 - 75,200,287RGD_MAPPER_PIPELINERnor5.0
Rnor_5.01375,200,283 - 75,200,287RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41143,415,816 - 143,603,554RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.41367,806,516 - 67,834,105RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Nox4em2Mcwi-var1 chr1 150861996 150862003 ACCTATGC - deletion Rnor_6.0
Ncf2em1Mcwi-var1 chr13 75200283 75200287 GAGAA - deletion Rnor_5.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-01 SS-Nox4em2Ncf2em1Mcwi    SS-Nox4em2Ncf2em1MCWi    Symbol updated 68687 APPROVED
2018-02-01 SS-Nox4em2Ncf2em1Mcwi    SS-Nox4em2Ncf2em1MCWi    Symbol updated 68687 APPROVED