Atrn (attractin) - Rat Genome Database

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Gene: Atrn (attractin) Rattus norvegicus
Analyze
Symbol: Atrn
Name: attractin
RGD ID: 69063
Description: Predicted to enable Notch binding activity and signaling receptor activity. Involved in pigmentation and response to oxidative stress. Predicted to be located in extracellular space. Orthologous to human ATRN (attractin); PARTICIPATES IN melanocortin system pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: membrane attractin; protein zitter
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Atrnzi   Atrnmv  
Genetic Models: ZI/Kyo MV/Opu
Is Marker For: Strains:   ZIMY/Kyo   SER/Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)41Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)104Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)3Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)20Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)21Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)22Kyo  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,110,320 - 118,244,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,110,229 - 118,244,322 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,004,507 - 122,138,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,602,558 - 130,736,641 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,260,615 - 128,394,765 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,434,409 - 123,567,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,434,409 - 123,567,918 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,934,303 - 130,067,267 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,539,268 - 118,701,177 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,444,840 - 118,606,746 (+)NCBI
Celera3116,920,666 - 117,054,199 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
atrazine  (EXP)
benzene  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cobalt dichloride  (ISO)
coumarin  (EXP,ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
flutamide  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
lactacystin  (ISO)
menadione  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel sulfate  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Melanocortin receptors and their accessory proteins. Cooray SN and Clark AJ, Mol Cell Endocrinol. 2011 Jan 15;331(2):215-21. Epub 2010 Jul 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Insertional mutation of the Attractin gene in the black tremor hamster. Kuramoto T, etal., Mamm Genome 2002 Jan;13(1):36-40.
5. Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system. Kuramoto T, etal., Proc Natl Acad Sci U S A 2001 Jan 16;98(2):559-64.
6. The myelin vacuolation (mv) rat with a null mutation in the attractin gene. Kuwamura M, etal., Lab Invest 2002 Oct;82(10):1279-86.
7. Zhonghua nan ke xue = National journal of andrology Liu J and Xiong C, Zhonghua Nan Ke Xue. 2004 Jul;10(7):515-7, 520.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Pivotal role of attractin in cell survival under oxidative stress in the zitter rat brain with genetic spongiform encephalopathy. Muto Y and Sato K, Brain Res Mol Brain Res 2003 Mar 17;111(1-2):111-22.
10. The mahogany protein is a receptor involved in suppression of obesity. Nagle DL, etal., Nature 1999 Mar 11;398(6723):148-52.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11137996   PMID:15682487   PMID:16502470   PMID:17261078   PMID:18064672   PMID:18206135   PMID:18302151   PMID:19056867   PMID:19931230   PMID:23376485   PMID:23533145   PMID:36621889  


Genomics

Comparative Map Data
Atrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,110,320 - 118,244,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,110,229 - 118,244,322 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,004,507 - 122,138,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,602,558 - 130,736,641 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,260,615 - 128,394,765 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,434,409 - 123,567,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,434,409 - 123,567,918 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,934,303 - 130,067,267 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,539,268 - 118,701,177 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,444,840 - 118,606,746 (+)NCBI
Celera3116,920,666 - 117,054,199 (+)NCBICelera
Cytogenetic Map3q36NCBI
ATRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,471,018 - 3,651,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,471,018 - 3,651,118 (+)EnsemblGRCh38hg38GRCh38
GRCh37203,451,665 - 3,631,765 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,399,676 - 3,579,765 (+)NCBINCBI36Build 36hg18NCBI36
Build 34203,399,675 - 3,544,704NCBI
Celera203,513,657 - 3,693,655 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,399,541 - 3,580,108 (+)NCBIHuRef
CHM1_1203,451,974 - 3,632,086 (+)NCBICHM1_1
T2T-CHM13v2.0203,501,888 - 3,682,059 (+)NCBIT2T-CHM13v2.0
Atrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,734,363 - 130,872,249 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,748,415 - 130,872,253 (+)EnsemblGRCm39 Ensembl
GRCm382130,906,430 - 131,030,333 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,906,495 - 131,030,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv372130,732,232 - 130,856,065 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,597,937 - 130,721,770 (+)NCBIMGSCv36mm8
Celera2132,131,227 - 132,255,065 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
Atrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,340,403 - 14,506,024 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,341,635 - 14,505,955 (+)NCBIChiLan1.0ChiLan1.0
ATRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1204,434,306 - 4,611,266 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,556,445 - 3,733,322 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,315,241 - 3,490,901 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,315,278 - 3,486,628 (+)Ensemblpanpan1.1panPan2
ATRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,698,238 - 17,859,810 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,702,282 - 17,859,737 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,528,104 - 17,688,488 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,117,068 - 18,278,292 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,118,872 - 18,278,215 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,766,353 - 17,872,211 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,823,557 - 17,984,479 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,150,655 - 18,311,906 (-)NCBIUU_Cfam_GSD_1.0
ATRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,054,249 - 32,239,519 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,054,240 - 32,239,576 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,381,687 - 36,516,383 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,157,240 - 34,335,902 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl234,157,293 - 34,335,923 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,118,786 - 10,244,152 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,559,121 - 4,745,996 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,559,149 - 4,745,840 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atrn
292 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:590
Count of miRNA genes:270
Interacting mature miRNAs:365
Transcripts:ENSRNOT00000028847
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat

Markers in Region
D3Rat160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,235,304 - 118,235,429 (+)MAPPERmRatBN7.2
Rnor_6.03123,558,901 - 123,559,025NCBIRnor6.0
Rnor_5.03130,058,246 - 130,058,370UniSTSRnor5.0
RGSC_v3.43118,692,155 - 118,692,280RGDRGSC3.4
RGSC_v3.43118,692,156 - 118,692,280UniSTSRGSC3.4
RGSC_v3.13118,597,433 - 118,597,950RGD
Celera3117,045,178 - 117,045,302UniSTS
RH 2.0 Map3689.5RGD
SHRSP x BN Map357.4399RGD
Cytogenetic Map3q36UniSTS
RH131001  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,243,899 - 118,244,086 (+)MAPPERmRatBN7.2
Rnor_6.03123,567,496 - 123,567,682NCBIRnor6.0
Rnor_5.03130,066,841 - 130,067,027UniSTSRnor5.0
RGSC_v3.43118,700,751 - 118,700,937UniSTSRGSC3.4
Celera3117,053,773 - 117,053,959UniSTS
RH 3.4 Map31013.0UniSTS
Cytogenetic Map3q36UniSTS
RH131613  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,190,135 - 118,190,320 (+)MAPPERmRatBN7.2
Rnor_6.03123,513,347 - 123,513,531NCBIRnor6.0
Rnor_5.03130,013,468 - 130,013,652UniSTSRnor5.0
RGSC_v3.43118,646,591 - 118,646,775UniSTSRGSC3.4
Celera3116,999,898 - 117,000,082UniSTS
RH 3.4 Map31019.5UniSTS
Cytogenetic Map3q36UniSTS
BF392025  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,205,695 - 118,205,800 (+)MAPPERmRatBN7.2
Rnor_6.03123,528,839 - 123,528,943NCBIRnor6.0
Rnor_5.03130,028,329 - 130,028,433UniSTSRnor5.0
RGSC_v3.43118,662,114 - 118,662,218UniSTSRGSC3.4
Celera3117,015,515 - 117,015,619UniSTS
RH 3.4 Map31019.5UniSTS
Cytogenetic Map3q36UniSTS
PMC14626P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,180,561 - 118,180,696 (+)MAPPERmRatBN7.2
Rnor_6.03123,503,772 - 123,503,906NCBIRnor6.0
Rnor_5.03130,003,893 - 130,004,027UniSTSRnor5.0
RGSC_v3.43118,637,016 - 118,637,150UniSTSRGSC3.4
Celera3116,990,349 - 116,990,483UniSTS
Cytogenetic Map3q36UniSTS
AI101364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,213,888 - 118,213,981 (+)MAPPERmRatBN7.2
Rnor_6.03123,537,024 - 123,537,116NCBIRnor6.0
Rnor_5.03130,036,514 - 130,036,606UniSTSRnor5.0
RGSC_v3.43118,670,299 - 118,670,391UniSTSRGSC3.4
Celera3117,023,696 - 117,023,788UniSTS
RH 3.4 Map31019.5UniSTS
Cytogenetic Map3q36UniSTS




Genetic Models
This gene Atrn is modified in the following models/strains:
ZI/Kyo     MV/Opu    


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 42 47 31 19 31 7 7 74 35 37 11 7
Low 1 1 10 10 10 1 4 4 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000028847   ⟹   ENSRNOP00000028847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,110,229 - 118,244,322 (+)Ensembl
Rnor_6.0 Ensembl3123,434,409 - 123,567,918 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104219   ⟹   ENSRNOP00000097783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,110,380 - 118,244,322 (+)Ensembl
RefSeq Acc Id: NM_031351   ⟹   NP_112641
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,110,320 - 118,244,326 (+)NCBI
Rnor_6.03123,434,409 - 123,567,922 (+)NCBI
Rnor_5.03129,934,303 - 130,067,267 (+)NCBI
RGSC_v3.43118,539,268 - 118,701,177 (+)RGD
Celera3116,920,666 - 117,054,199 (+)RGD
Sequence:
RefSeq Acc Id: NP_112641   ⟸   NM_031351
- Peptide Label: precursor
- UniProtKB: Q99PW0 (UniProtKB/Swiss-Prot),   Q99J86 (UniProtKB/Swiss-Prot),   A6HQB3 (UniProtKB/TrEMBL),   A0A8I6AUX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028847   ⟸   ENSRNOT00000028847
RefSeq Acc Id: ENSRNOP00000097783   ⟸   ENSRNOT00000104219
Protein Domains
C-type lectin   CUB   EGF-like   Laminin EGF-like   PSI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99J86-F1-model_v2 AlphaFold Q99J86 1-1432 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692442
Promoter ID:EPDNEW_R2966
Type:initiation region
Name:Atrn_1
Description:attractin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03123,434,436 - 123,434,496EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69063 AgrOrtholog
BioCyc Gene G2FUF-47833 BioCyc
Ensembl Genes ENSRNOG00000021240 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028847 ENTREZGENE
  ENSRNOT00000028847.5 UniProtKB/TrEMBL
  ENSRNOT00000104219.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.290 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUB_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gal_Oxase/kelch_b-propeller UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83526 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 83526 ENTREZGENE
PANTHER ATTRACTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ATRN RGD
PhenoGen Atrn PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021240 RatGTEx
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Lam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch motif UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF49854 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50965 UniProtKB/TrEMBL
  SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC205110
  TC205111
UniProt A0A8I6AUX0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QFH6_RAT UniProtKB/TrEMBL
  A6HQB3 ENTREZGENE, UniProtKB/TrEMBL
  A6HQB4_RAT UniProtKB/TrEMBL
  A6HQB5_RAT UniProtKB/TrEMBL
  ATRN_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q99PW0 ENTREZGENE
UniProt Secondary Q99PW0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Atrn  attractin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease responsible for dark coat color and nuerological defects 70520
gene_disease 8-bp deletion at a splice donor site responsible for the zitter (zi) mutation which induces hypomyelination and vacuolation in the central nervous system 67998
gene_disease genomic deletion including exon 1 is responsible for the myelin vacuolation (mv) rat 1299186
gene_process regulates monocyte-T cell interaction, energy homeostasis, and agouti-related hair pigmentation 67998
gene_process involved in monocyte-T cell interaction, agouti-related hair pigmentation, and control of energy homeostasis 67998
gene_process increases cell survival against oxidative stress 1299185