Atrn (attractin) - Rat Genome Database

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Gene: Atrn (attractin) Rattus norvegicus
Analyze
Symbol: Atrn
Name: attractin
RGD ID: 69063
Description: Predicted to enable signaling receptor activity. Involved in pigmentation and response to oxidative stress. Located in cytoplasm and plasma membrane. Orthologous to human ATRN (attractin); PARTICIPATES IN melanocortin system pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: membrane attractin; protein zitter
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Atrnzi   Atrnmv  
Genetic Models: ZI/Kyo MV/Opu
Is Marker For: Strains:   ZIMY/Kyo   SER/Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)41Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)104Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)3Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)20Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)21Kyo   W-Tg(RNB1-116K03-EGFP-mRFP)22Kyo  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,110,320 - 118,244,326 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3118,110,229 - 118,244,322 (+)Ensembl
Rnor_6.03123,434,409 - 123,567,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,434,409 - 123,567,918 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,934,303 - 130,067,267 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,539,268 - 118,701,177 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,444,840 - 118,606,746 (+)NCBI
Celera3116,920,666 - 117,054,199 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:11137996   PMID:15682487   PMID:16502470   PMID:17261078   PMID:18064672   PMID:18206135   PMID:18302151   PMID:19056867   PMID:19931230   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Atrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,110,320 - 118,244,326 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3118,110,229 - 118,244,322 (+)Ensembl
Rnor_6.03123,434,409 - 123,567,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,434,409 - 123,567,918 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,934,303 - 130,067,267 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,539,268 - 118,701,177 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,444,840 - 118,606,746 (+)NCBI
Celera3116,920,666 - 117,054,199 (+)NCBICelera
Cytogenetic Map3q36NCBI
ATRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,471,018 - 3,651,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl203,471,018 - 3,651,118 (+)EnsemblGRCh38hg38GRCh38
GRCh37203,451,665 - 3,631,765 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,399,676 - 3,579,765 (+)NCBINCBI36hg18NCBI36
Build 34203,399,675 - 3,544,704NCBI
Celera203,513,657 - 3,693,655 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef203,399,541 - 3,580,108 (+)NCBIHuRef
CHM1_1203,451,974 - 3,632,086 (+)NCBICHM1_1
Atrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,734,363 - 130,872,249 (+)NCBIGRCm39mm39
GRCm39 Ensembl2130,748,415 - 130,872,253 (+)Ensembl
GRCm382130,906,430 - 131,030,333 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,906,495 - 131,030,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv372130,732,232 - 130,856,065 (+)NCBIGRCm37mm9NCBIm37
MGSCv362130,597,937 - 130,721,770 (+)NCBImm8
Celera2132,131,227 - 132,255,065 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
Atrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,340,403 - 14,506,024 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,341,635 - 14,505,955 (+)NCBIChiLan1.0ChiLan1.0
ATRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1203,315,241 - 3,490,901 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,315,278 - 3,486,628 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0203,556,445 - 3,733,322 (+)NCBIMhudiblu_PPA_v0panPan3
ATRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,698,238 - 17,859,810 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,702,282 - 17,859,737 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,528,104 - 17,688,488 (-)NCBI
ROS_Cfam_1.02418,117,068 - 18,278,292 (-)NCBI
ROS_Cfam_1.0 Ensembl2418,118,872 - 18,278,215 (-)Ensembl
UMICH_Zoey_3.12417,766,353 - 17,872,211 (-)NCBI
UNSW_CanFamBas_1.02417,823,557 - 17,984,479 (-)NCBI
UU_Cfam_GSD_1.02418,150,655 - 18,311,906 (-)NCBI
ATRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,054,242 - 32,239,574 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,054,240 - 32,239,576 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,381,687 - 36,516,383 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,157,240 - 34,335,902 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl234,157,293 - 34,335,923 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607110,118,786 - 10,244,152 (-)NCBIVero_WHO_p1.0
Atrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247414,559,149 - 4,745,840 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Rat160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,235,304 - 118,235,429 (+)MAPPERmRatBN7.2
Rnor_6.03123,558,901 - 123,559,025NCBIRnor6.0
Rnor_5.03130,058,246 - 130,058,370UniSTSRnor5.0
RGSC_v3.43118,692,156 - 118,692,280UniSTSRGSC3.4
RGSC_v3.43118,692,155 - 118,692,280RGDRGSC3.4
RGSC_v3.13118,597,433 - 118,597,950RGD
Celera3117,045,178 - 117,045,302UniSTS
RH 2.0 Map3689.5RGD
SHRSP x BN Map357.4399RGD
Cytogenetic Map3q36UniSTS
RH131001  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,243,899 - 118,244,086 (+)MAPPERmRatBN7.2
Rnor_6.03123,567,496 - 123,567,682NCBIRnor6.0
Rnor_5.03130,066,841 - 130,067,027UniSTSRnor5.0
RGSC_v3.43118,700,751 - 118,700,937UniSTSRGSC3.4
Celera3117,053,773 - 117,053,959UniSTS
RH 3.4 Map31013.0UniSTS
Cytogenetic Map3q36UniSTS
RH131613  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,190,135 - 118,190,320 (+)MAPPERmRatBN7.2
Rnor_6.03123,513,347 - 123,513,531NCBIRnor6.0
Rnor_5.03130,013,468 - 130,013,652UniSTSRnor5.0
RGSC_v3.43118,646,591 - 118,646,775UniSTSRGSC3.4
Celera3116,999,898 - 117,000,082UniSTS
RH 3.4 Map31019.5UniSTS
Cytogenetic Map3q36UniSTS
BF392025  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,205,695 - 118,205,800 (+)MAPPERmRatBN7.2
Rnor_6.03123,528,839 - 123,528,943NCBIRnor6.0
Rnor_5.03130,028,329 - 130,028,433UniSTSRnor5.0
RGSC_v3.43118,662,114 - 118,662,218UniSTSRGSC3.4
Celera3117,015,515 - 117,015,619UniSTS
RH 3.4 Map31019.5UniSTS
Cytogenetic Map3q36UniSTS
PMC14626P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,180,561 - 118,180,696 (+)MAPPERmRatBN7.2
Rnor_6.03123,503,772 - 123,503,906NCBIRnor6.0
Rnor_5.03130,003,893 - 130,004,027UniSTSRnor5.0
RGSC_v3.43118,637,016 - 118,637,150UniSTSRGSC3.4
Celera3116,990,349 - 116,990,483UniSTS
Cytogenetic Map3q36UniSTS
AI101364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,213,888 - 118,213,981 (+)MAPPERmRatBN7.2
Rnor_6.03123,537,024 - 123,537,116NCBIRnor6.0
Rnor_5.03130,036,514 - 130,036,606UniSTSRnor5.0
RGSC_v3.43118,670,299 - 118,670,391UniSTSRGSC3.4
Celera3117,023,696 - 117,023,788UniSTS
RH 3.4 Map31019.5UniSTS
Cytogenetic Map3q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat




Genetic Models
This gene Atrn is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:590
Count of miRNA genes:270
Interacting mature miRNAs:365
Transcripts:ENSRNOT00000028847
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 42 47 31 19 31 7 7 74 35 37 11 7
Low 1 1 10 10 10 1 4 4 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000028847   ⟹   ENSRNOP00000028847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,110,229 - 118,244,322 (+)Ensembl
Rnor_6.0 Ensembl3123,434,409 - 123,567,918 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104219   ⟹   ENSRNOP00000097783
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,110,380 - 118,244,322 (+)Ensembl
RefSeq Acc Id: NM_031351   ⟹   NP_112641
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,110,320 - 118,244,326 (+)NCBI
Rnor_6.03123,434,409 - 123,567,922 (+)NCBI
Rnor_5.03129,934,303 - 130,067,267 (+)NCBI
RGSC_v3.43118,539,268 - 118,701,177 (+)RGD
Celera3116,920,666 - 117,054,199 (+)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_112641   ⟸   NM_031351
- Peptide Label: precursor
- UniProtKB: Q99J86 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028847   ⟸   ENSRNOT00000028847
RefSeq Acc Id: ENSRNOP00000097783   ⟸   ENSRNOT00000104219
Protein Domains
C-type lectin   CUB   EGF-like   Laminin EGF-like   PSI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99J86-F1-model_v2 AlphaFold Q99J86 1-1432 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692442
Promoter ID:EPDNEW_R2966
Type:initiation region
Name:Atrn_1
Description:attractin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03123,434,436 - 123,434,496EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69063 AgrOrtholog
BioCyc Gene G2FUF-47833 BioCyc
Ensembl Genes ENSRNOG00000021240 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000028847 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028847 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.120.10.80 UniProtKB/Swiss-Prot
  2.60.120.290 UniProtKB/Swiss-Prot
  3.10.100.10 UniProtKB/Swiss-Prot
InterPro C-type_lectin-like UniProtKB/Swiss-Prot
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot
  CTDL_fold UniProtKB/Swiss-Prot
  CUB_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  Laminin_EGF UniProtKB/Swiss-Prot
  Plexin_repeat UniProtKB/Swiss-Prot
  PSI UniProtKB/Swiss-Prot
  Sperma_CUB_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:83526 UniProtKB/Swiss-Prot
NCBI Gene 83526 ENTREZGENE
Pfam CUB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  Lectin_C UniProtKB/Swiss-Prot
  PSI UniProtKB/Swiss-Prot
PharmGKB ATRN RGD
PhenoGen Atrn PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot
  CUB UniProtKB/Swiss-Prot
  EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_LAM_1 UniProtKB/Swiss-Prot
  EGF_LAM_2 UniProtKB/Swiss-Prot
SMART CLECT UniProtKB/Swiss-Prot
  CUB UniProtKB/Swiss-Prot
  EGF UniProtKB/Swiss-Prot
  EGF_Lam UniProtKB/Swiss-Prot
  PSI UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF49854 UniProtKB/Swiss-Prot
  SSF56436 UniProtKB/Swiss-Prot
TIGR TC205110
  TC205111
UniProt ATRN_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q99PW0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Atrn  attractin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease responsible for dark coat color and nuerological defects 70520
gene_disease 8-bp deletion at a splice donor site responsible for the zitter (zi) mutation which induces hypomyelination and vacuolation in the central nervous system 67998
gene_disease genomic deletion including exon 1 is responsible for the myelin vacuolation (mv) rat 1299186
gene_process regulates monocyte-T cell interaction, energy homeostasis, and agouti-related hair pigmentation 67998
gene_process involved in monocyte-T cell interaction, agouti-related hair pigmentation, and control of energy homeostasis 67998
gene_process increases cell survival against oxidative stress 1299185