Esr2 (estrogen receptor 2) - Rat Genome Database

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Gene: Esr2 (estrogen receptor 2) Rattus norvegicus
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Symbol: Esr2
Name: estrogen receptor 2
RGD ID: 2582
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; estrogen response element binding activity; and peroxisome proliferator activated receptor binding activity. Involved in several processes, including animal organ development; regulation of neuron death; and response to steroid hormone. Localizes to several cellular components, including mitochondrion; perikaryon; and perinuclear region of cytoplasm. Used to study several diseases, including hypertension (multiple); obesity; peritonitis; prostate carcinoma in situ; and transient cerebral ischemia. Biomarker of asthma; brain ischemia; colitis; cystitis; and osteoporosis. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); hypospadias; neurodegenerative disease (multiple); and ovarian dysgenesis 8. Orthologous to human ESR2 (estrogen receptor 2); PARTICIPATES IN estrogen signaling pathway; bisphenol A response pathway; tamoxifen pharmacodynamics pathway; INTERACTS WITH (+)-alpha-tocopherol; (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ER-beta; Erb2; ERbeta; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; estrogen receptor beta; nuclear receptor subfamily 3 group A member 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Esr2em1Soar  
Genetic Models: SD-Esr2em1Soar
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2694,858,438 - 94,909,630 (-)NCBI
Rnor_6.0 Ensembl699,164,357 - 99,214,251 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0699,163,953 - 99,214,711 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06108,576,398 - 108,626,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4698,691,167 - 98,775,299 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1698,694,622 - 98,778,755 (-)NCBI
Celera693,284,596 - 93,334,744 (-)NCBICelera
RH 3.4 Map6686.1RGD
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenocarcinoma  (ISO)
adenoma  (ISO)
alopecia  (ISO)
Alzheimer's disease  (ISO)
Animal Mammary Neoplasms  (ISO)
anxiety disorder  (IDA)
aortic valve stenosis  (ISO)
asthma  (IEP)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
Blast Crisis  (ISO)
brain ischemia  (IEP)
breast cancer  (IDA,ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
Cardiac Arrhythmias  (ISO)
Cocaine-Related Disorders  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (IEP,ISO)
colon cancer  (IDA)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
contact dermatitis  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cystitis  (IEP)
Deafness  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
Experimental Arthritis  (IDA)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Melanoma  (ISO)
Female Infertility  (IMP,ISO)
glomerulosclerosis  (ISO)
Graves' disease  (ISO)
Hand Osteoarthritis  (ISO)
Hashimoto Disease  (ISO)
Hearing Loss  (ISO)
Hemorrhagic Shock  (IDA)
Hot Flashes  (IDA)
Hyperalgesia  (IDA,ISO)
hypertension  (IMP,ISO)
hypospadias  (ISO)
in situ carcinoma  (ISO)
inflammatory bowel disease  (IDA)
interstitial cystitis  (ISO)
Knee Osteoarthritis  (ISO)
Left Ventricular Hypertrophy  (ISO)
Lithiasis  (ISO)
Lung Injury  (IDA)
malignant astrocytoma  (ISO)
Mammary Neoplasms, Experimental  (IDA,IEP,ISO)
medulloblastoma  (ISO)
melanoma  (ISO)
mental depression  (IDA)
myasthenia gravis  (ISO)
myeloid leukemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
obesity  (IDA)
osteoarthritis  (ISO)
osteoporosis  (IEP,ISO)
Osteoporotic Fractures  (IEP,ISO)
ovarian dysgenesis 8  (ISO)
Parkinson's disease  (ISO)
peritonitis  (IDA)
Pituitary Neoplasms  (ISO)
Postmenopausal Osteoporosis  (ISO)
pre-eclampsia  (ISO)
primary open angle glaucoma  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (IDA,ISO)
prostatic hypertrophy  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (IDA)
retinal degeneration  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (IDA)
Spinal Cord Injuries  (IEP)
Splenomegaly  (ISO)
Stroke  (IDA)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
transient cerebral ischemia  (IMP)
transitional cell carcinoma  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Urination Disorders  (IDA)
Varicose Ulcer  (ISO)
Vulvar Lichen Sclerosus  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(24S)-24-hydroxycholesterol  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(S)-naringenin  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1-bromopropane  (ISO)
1-Hydroxypyrene  (ISO)
1-naphthol  (ISO)
16-Ketoestrone  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2'-Dihydroxy-4-methoxybenzophenone  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,4,5-Tetrachloro-4'-biphenylol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dichlorophenol  (ISO)
2,4-Dihydroxybenzophenone  (ISO)
2,6-diisopropylnaphthalene  (ISO)
2,6-dimethylnaphthalene  (ISO)
2-hydroxy-17beta-estradiol  (EXP,ISO)
2-hydroxyestrone  (ISO)
2-tert-Butylphenol  (ISO)
22-Hydroxycholesterol  (ISO)
25-hydroxycholesterol  (ISO)
26-hydroxycholesterol  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3,3'-diindolylmethane  (ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-ethylphenol  (ISO)
4-hydroxy-17beta-estradiol  (EXP,ISO)
4-Hydroxybenzophenone  (ISO)
4-nitrophenol  (EXP)
4-nitrotoluene  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
4-Propylphenol  (ISO)
4-tert-Octylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-oxocampestanol  (ISO)
8-Br-cAMP  (ISO)
9,9-bis(4-hydroxyphenyl)fluorene  (ISO)
9-cis-retinoic acid  (ISO)
9-phenanthrol  (ISO)
acetophenone  (ISO)
acrylamide  (ISO)
adenosine  (ISO)
afimoxifene  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aldrin  (ISO)
all-trans-phytoene  (ISO)
all-trans-phytofluene  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-naphthoflavone  (EXP)
alpha-Zearalanol  (EXP,ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
ammonium chloride  (EXP)
androgen antagonist  (EXP)
androst-5-ene-3beta,17beta-diol  (EXP,ISO)
androstane-3,17-diol  (EXP,ISO)
anilines  (ISO)
apigenin  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
azadirachtin A  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
benzophenone  (ISO)
benzyl benzoate  (ISO)
Benzyl parahydroxybenzoate  (ISO)
Benzyl salicylate  (ISO)
beta-carotene  (ISO)
beta-hexachlorocyclohexane  (ISO)
beta-naphthoflavone  (EXP)
beta-tocopherol  (EXP)
bexarotene  (ISO)
bicalutamide  (ISO)
biochanin A  (EXP,ISO)
biphenyl-2-ol  (ISO)
biphenyl-4-ol  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
brassinolide  (ISO)
Bromofos  (ISO)
Bromophos-ethyl  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
butylbenzene  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (EXP,ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
camptothecin  (ISO)
carbaryl  (ISO)
carbendazim  (EXP)
carbon nanotube  (ISO)
carfilzomib  (ISO)
cedrol  (ISO)
chlordecone  (ISO)
chlorogenic acid  (EXP)
chloropropylate  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (EXP)
chrysin  (ISO)
cisplatin  (ISO)
citral  (ISO)
clomiphene  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumestrol  (EXP,ISO)
cyanazine  (ISO)
Cyanofenphos  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
daidzein  (EXP,ISO)
daidzein 7-O-beta-D-glucoside  (EXP)
DDD  (ISO)
DDE  (EXP,ISO)
DDT  (EXP,ISO)
dehydroepiandrosterone  (ISO)
delta-hexachlorocyclohexane  (ISO)
delta-tocopherol  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Di-n-hexyl phthalate  (ISO)
Di-n-octyl phthalate  (ISO)
diarsenic trioxide  (ISO)
diarylheptanoid  (ISO)
dibutyl phthalate  (EXP,ISO)
Dichlofenthion  (ISO)
dicofol  (ISO)
Dicyclohexyl phthalate  (ISO)
dieldrin  (ISO)
dienestrol  (EXP)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP,ISO)
digitoxin  (ISO)
diheptyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
dimethoate  (ISO)
dioscin  (ISO)
diosgenin  (ISO)
dioxygen  (EXP)
dipentyl phthalate  (ISO)
diphenylmethanol  (ISO)
dipropyl phthalate  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
dronedarone  (ISO)
emetine  (ISO)
emodin  (ISO)
endosulfan  (EXP,ISO)
endrin  (ISO)
enilconazole  (ISO)
enzacamene  (EXP,ISO)
EPN  (ISO)
equol  (ISO)
estriol  (EXP,ISO)
estrone  (EXP,ISO)
ethanol  (EXP)
ethion  (ISO)
Ethyl cinnamate  (ISO)
ethyl myristate  (ISO)
ethylparaben  (EXP,ISO)
etoposide  (ISO)
eugenol  (ISO)
fenarimol  (ISO)
fenbuconazole  (ISO)
fenhexamid  (ISO)
fenpyroximate  (ISO)
fenvalerate  (ISO)
fingolimod hydrochloride  (ISO)
fipronil  (ISO)
flavone  (ISO)
fludioxonil  (ISO)
fluoxastrobin  (ISO)
flutamide  (EXP,ISO)
formononetin  (ISO)
fulvestrant  (EXP,ISO)
galaxolide  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-tocopherol  (EXP)
gefitinib  (ISO)
genistein  (EXP,ISO)
genistein 7-O-beta-D-glucoside  (EXP)
geranial  (ISO)
geraniol  (ISO)
glucose  (ISO)
glycitein  (EXP,ISO)
glycitin  (EXP)
glyphosate  (EXP,ISO)
heptachlor  (ISO)
Heptachlor epoxide  (ISO)
herbicide  (ISO)
hexestrol  (EXP)
hydrogencarbonate  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
indinavir  (ISO)
indoles  (ISO)
ipriflavone  (ISO)
irilone  (ISO)
isoflavones  (EXP,ISO)
isorhamnetin  (ISO)
isotretinoin  (EXP)
kaempferol  (EXP,ISO)
kresoxim-methyl  (ISO)
L-ascorbic acid  (EXP)
lamivudine  (ISO)
lasofoxifene  (EXP)
leptophos  (ISO)
lipopolysaccharide  (ISO)
liquiritigenin  (ISO)
luteolin  (ISO)
lycopene  (ISO)
M1  (ISO)
melatonin  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
mestranol  (ISO)
metformin  (EXP)
methimazole  (ISO)
methiocarb  (ISO)
methoxyacetic acid  (EXP,ISO)
methoxychlor  (EXP,ISO)
methyl laurate  (ISO)
Methyl palmitate  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
mifepristone  (EXP,ISO)
Mitotane  (ISO)
MK 571  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
monoethyl phthalate  (ISO)
Moxestrol  (EXP)
mycophenolic acid  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-BUTYL-11-[(7R,8R,9S,13S,14S,17S)-3,17-DIHYDROXY-13-METHYL-7,8,9,11,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHREN-7-YL]-N-METHYLUNDECANAMIDE  (EXP)
N-butylbenzenesulfonamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
n-propyl gallate  (ISO)
Nafoxidine  (EXP)
naringin  (EXP)
nebivolol  (ISO)
Nonylphenol  (ISO)
norethisterone  (ISO)
notoginsenoside R1  (EXP)
nuarimol  (ISO)
O-Desmethylangolensin  (ISO)
octocrylene  (ISO)
ormeloxifene  (EXP)
Osajin  (ISO)
oxybenzone  (EXP,ISO)
p-tert-Amylphenol  (ISO)
p-tolualdehyde  (ISO)
paclitaxel  (ISO)
pendimethalin  (EXP,ISO)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenanthrene  (ISO)
phenothrin  (ISO)
PhIP  (EXP)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phthalic acid  (ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
Pomiferin  (ISO)
prochloraz  (ISO)
progesterone  (EXP,ISO)
propamocarb  (ISO)
propylparaben  (EXP,ISO)
prothiofos  (ISO)
pterostilbene  (ISO)
puerarin  (EXP,ISO)
pyrazoles  (ISO)
pyridaben  (ISO)
quercetin  (ISO)
quinalphos  (ISO)
raloxifene  (EXP,ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
rifapentine  (ISO)
Rosavin  (ISO)
rotenone  (ISO)
royal jelly  (ISO)
rubitecan  (ISO)
rutin  (EXP)
salicylates  (ISO)
saquinavir  (ISO)
SB 203580  (ISO)
serpentine asbestos  (ISO)
silibinin  (EXP,ISO)
sodium arsenite  (ISO)
sodium hypochlorite  (ISO)
sophoraflavanone B  (EXP,ISO)
staurosporine  (ISO)
streptozocin  (ISO)
tamoxifen  (EXP,ISO)
teniposide  (ISO)
testosterone  (EXP,ISO)
Tetrachlorobisphenol A  (ISO)
tetrachloromethane  (EXP)
tetradifon  (ISO)
tetralin  (ISO)
tetramethrin  (EXP)
tibolone  (ISO)
tolclofos-methyl  (ISO)
topotecan  (ISO)
toremifene  (ISO)
toxaphene  (EXP,ISO)
trans-piceid  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (EXP,ISO)
trifloxystrobin  (ISO)
trifluridine  (ISO)
trilostane  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
undecan-2-one  (ISO)
valinomycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP,ISO)
vinyl carbamate  (ISO)
vitamin E  (EXP)
zearalenone  (EXP,ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amygdala development  (IEP)
behavioral fear response  (IDA)
brain development  (ISO)
cellular response to drug  (IEP)
cellular response to estradiol stimulus  (IEA,IEP,ISO)
cellular response to magnetism  (IEP)
cellular response to organic cyclic compound  (IEP)
cerebellum development  (IEP)
epithelial cell maturation involved in prostate gland development  (ISO)
estrous cycle  (IMP)
female gonad development  (IEP)
hormone-mediated apoptotic signaling pathway  (ISO)
hypothalamus development  (IEP)
intracellular estrogen receptor signaling pathway  (IEA,ISO,TAS)
intracellular steroid hormone receptor signaling pathway  (IBA,IDA)
learning or memory  (IMP)
male gonad development  (IEP)
negative regulation of androgen receptor signaling pathway  (ISO)
negative regulation of behavior  (IDA)
negative regulation of cell death  (IMP)
negative regulation of cell population proliferation  (ISO)
negative regulation of epithelial cell proliferation  (IDA,ISO)
negative regulation of feeding behavior  (IMP)
negative regulation of neuron death  (IDA)
negative regulation of reactive oxygen species metabolic process  (IMP)
negative regulation of smooth muscle cell proliferation  (IMP)
negative regulation of transcription by RNA polymerase II  (IDA,IEA,ISO)
neuron migration  (ISO)
ovarian follicle development  (IEP,ISO)
positive regulation of apoptotic process  (IDA)
positive regulation of DNA-binding transcription factor activity  (IEA,ISO,ISS)
positive regulation of epidermal growth factor receptor signaling pathway  (IMP)
positive regulation of ERK1 and ERK2 cascade  (IDA,IMP)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
positive regulation of transcription, DNA-templated  (IDA,IEA,ISO)
prostate gland development  (IEP)
prostate gland epithelium morphogenesis  (ISO)
regulation of cell population proliferation  (ISO)
regulation of neuron apoptotic process  (IDA)
regulation of transcription by RNA polymerase II  (IBA)
regulation of transcription, DNA-templated  (IEA)
response to activity  (IEP)
response to bisphenol A  (IEP)
response to dexamethasone  (IEP)
response to drug  (IEP)
response to estradiol  (IEP)
response to estrogen  (IEP)
response to ethanol  (IEP)
response to genistein  (IEP)
response to hormone  (IEP)
response to human chorionic gonadotropin  (IEP)
response to insecticide  (IEP)
response to nutrient levels  (IEP)
response to organic cyclic compound  (IEP)
response to salt  (IEP)
response to testosterone  (IEP,IMP)
response to water deprivation  (IEP)
Sertoli cell development  (IEP)
Sertoli cell proliferation  (IMP)
steroid hormone mediated signaling pathway  (IEA)
uterus development  (ISO)
vagina development  (ISO)
vasodilation  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
1. Abbasi S BMC Med Genet. 2010 Jul 7;11:109. doi: 10.1186/1471-2350-11-109.
2. Acar D, etal., Neurourol Urodyn. 2007;26(2):309-16.
3. Alyea RA, etal., J Neurochem. 2008 Aug;106(4):1525-33. Epub 2008 May 19.
4. Arvanitis DN, etal., J Neurosci Res. 2004 Mar 1;75(5):603-13.
5. Ashworth JJ, etal., Clin Genet. 2008 Jan;73(1):55-61. Epub 2007 Nov 29.
6. Ashworth JJ, etal., J Steroid Biochem Mol Biol. 2005 Nov;97(3):266-70. Epub 2005 Sep 8.
7. Astiz M, etal., Neurotox Res. 2013 Aug 14.
8. Atawia RT, etal., Toxicol Lett. 2013 May 23;219(2):160-9. doi: 10.1016/j.toxlet.2013.03.002. Epub 2013 Mar 14.
9. Attia DM and Ederveen AG, Prostate. 2012 Jun 15;72(9):1013-22. doi: 10.1002/pros.21507. Epub 2011 Oct 24.
10. Bai Z and Gust R, Arch Pharm (Weinheim). 2009 Mar;342(3):133-49.
11. Ban Y, etal., BMC Med Genet. 2001;2:1. Epub 2001 Jan 31.
12. Beleza-Meireles A, etal., J Clin Endocrinol Metab. 2007 Jun 19;.
13. Blurton-Jones M, etal., J Comp Neurol. 2004 Jan 12;468(3):347-60.
14. Cao J and Patisaul HB, J Comp Neurol. 2013 Feb 1;521(2):465-78. doi: 10.1002/cne.23185.
15. Catanuto P, etal., Kidney Int. 2009 Jun;75(11):1194-201. doi: 10.1038/ki.2009.69. Epub 2009 Mar 11.
16. Catley MC, etal., J Pharmacol Exp Ther. 2008 Jul;326(1):83-8. doi: 10.1124/jpet.108.136275. Epub 2008 Mar 28.
17. Chen S, etal., PLoS One. 2013 Aug 27;8(8):e72428. doi: 10.1371/journal.pone.0072428.
18. Chen YC, etal., Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):1973-81.
19. Cheng CL and de Groat WC, Am J Physiol Renal Physiol. 2014 Jan;306(2):F181-7. doi: 10.1152/ajprenal.00298.2013. Epub 2013 Nov 20.
20. Cho JL, etal., Photochem Photobiol Sci. 2008 Jan;7(1):120-5. doi: 10.1039/b709856a. Epub 2007 Nov 2.
21. Cho JL, etal., Photochem Photobiol Sci. 2010 Apr;9(4):608-14. doi: 10.1039/b9pp00168a.
22. Choi JS and Song J, Nutrition. 2009 Jun;25(6):676-85. doi: 10.1016/j.nut.2008.11.027. Epub 2009 Feb 20.
23. Chow SK, etal., Arch Orthop Trauma Surg. 2014 Oct;134(10):1405-16. doi: 10.1007/s00402-014-2070-0. Epub 2014 Aug 2.
24. Christian RC, etal., J Clin Endocrinol Metab. 2006 Jul;91(7):2713-20. Epub 2006 Apr 11.
25. Chuffa LG, etal., Reprod Toxicol. 2013 Aug;39:40-9. doi: 10.1016/j.reprotox.2013.04.001. Epub 2013 Apr 13.
26. Cristofaro PA, etal., Crit Care Med. 2006 Aug;34(8):2188-93.
27. Daverey A, etal., J Steroid Biochem Mol Biol. 2009 Aug;116(1-2):93-101. Epub 2009 May 19.
28. de Giorgi V, etal., Arch Dermatol. 2009 Jan;145(1):30-6. doi: 10.1001/archdermatol.2008.537.
29. de Voogd S, etal., Arch Ophthalmol. 2008 Jan;126(1):110-4. doi: 10.1001/archopht.126.1.110.
30. Delfosse V, etal., Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14930-5. doi: 10.1073/pnas.1203574109. Epub 2012 Aug 27.
31. Doucet D, etal., PLoS One. 2010 Feb 25;5(2):e9421.
32. Du S, etal., Eur J Immunol. 2011 Jan;41(1):140-50. doi: 10.1002/eji.201040796. Epub 2010 Dec 9.
33. Dubal DB, etal., J Neurosci. 1999 Aug 1;19(15):6385-93.
34. Edinger KL and Frye CA, Neurobiol Learn Mem. 2007 Jan;87(1):78-85. Epub 2006 Aug 14.
35. Egawa C, etal., Oncology. 2001;61(4):293-8.
36. Elliot SJ, etal., Exp Eye Res. 2010 Jan;90(1):10-6. doi: 10.1016/j.exer.2009.09.001. Epub 2009 Sep 30.
37. Ellis JA, etal., J Hypertens. 2004 Jun;22(6):1127-31.
38. Faria Tda S, etal., J Endocrinol. 2008 Sep;198(3):625-34. doi: 10.1677/JOE-08-0121. Epub 2008 Jul 2.
39. Fitzpatrick SL, etal., Endocrinology. 1999 Jun;140(6):2581-91.
40. Follettie MT, etal., Endocrinology. 2006 Feb;147(2):714-23. Epub 2005 Nov 3.
41. Fytili P, etal., Clin Genet. 2005 Sep;68(3):268-77.
42. Gallicchio L, etal., BMC Cancer. 2006 Jun 29;6:173.
43. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
44. Geng L, etal., J Genet Genomics. 2007 Oct;34(10):868-76.
45. Ghorbanpoor S, etal., Endocrinology. 2014 Nov;155(11):4341-55. doi: 10.1210/en.2014-1158. Epub 2014 Aug 8.
46. Gittoes NJ, etal., Pituitary. 1999;1(2):99-104.
47. GOA data from the GO Consortium
48. Gold B, etal., Cancer Res. 2004 Dec 15;64(24):8891-900.
49. Grassi S, etal., Brain Res Bull. 2013 Aug;97:1-7. doi: 10.1016/j.brainresbull.2013.05.006. Epub 2013 May 20.
50. Guo C, etal., Endocrinology 2001 Jun;142(6):2230-7.
51. Harris HA, etal., Endocrinology. 2003 Oct;144(10):4241-9.
52. Harris HA, etal., Hum Reprod. 2005 Apr;20(4):936-41. Epub 2004 Dec 23.
53. He YX, etal., Bone. 2011 Jun 1;48(6):1388-400. doi: 10.1016/j.bone.2011.03.720. Epub 2011 Mar 21.
54. Hillisch A, etal., Mol Endocrinol. 2004 Jul;18(7):1599-609. Epub 2004 Apr 22.
55. Hogg ME, etal., J Surg Res. 2012 Mar;173(1):e1-10. doi: 10.1016/j.jss.2011.09.021. Epub 2011 Oct 8.
56. Hong-Goka BC and Chang FL, Neurosci Lett. 2004 Apr 29;360(3):113-6.
57. Honma N, etal., Histopathology. 2011 Aug;59(2):216-24. doi: 10.1111/j.1365-2559.2011.03914.x.
58. Honma N, etal., J Bone Miner Metab. 2013 Jan;31(1):96-101. doi: 10.1007/s00774-012-0383-z. Epub 2012 Sep 5.
59. Hoshi M, etal., Clin Exp Rheumatol. 2008 Sep-Oct;26(5):914-7.
60. Hoskins JM, etal., Nat Rev Cancer. 2009 Aug;9(8):576-86.
61. Hou NN, etal., Fen Zi Xi Bao Sheng Wu Xue Bao. 2006 Aug;39(4):289-96.
62. Hsieh YC, etal., J Mol Cell Cardiol. 2006 Sep;41(3):511-21. Epub 2006 Jul 21.
63. Ikeda Y and Nagai A, Brain Res. 2006 Apr 14;1083(1):39-49. Epub 2006 Mar 20.
64. Ikeda Y, etal., Endocrinology. 2003 Nov;144(11):5098-104. Epub 2003 Jul 24.
65. Imamov O, etal., Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9806-9. Epub 2007 May 23.
66. Inui A, etal., Clin Rheumatol. 2007 Oct;26(10):1675-8. Epub 2007 Feb 16.
67. Jankowski M, etal., Proc Natl Acad Sci U S A 2001 Sep 25;98(20):11765-70.
68. Jesmin S, etal., Endocrinology 2002 Dec;143(12):4764-74.
69. Kalita K, etal., Hippocampus. 2005;15(3):404-12.
70. Kauffman EC, etal., Oncol Rep. 2013 Jul;30(1):131-8. doi: 10.3892/or.2013.2416. Epub 2013 Apr 23.
71. Khristi V, etal., Mol Cell Endocrinol. 2018 Oct 15;474:214-226. doi: 10.1016/j.mce.2018.03.012. Epub 2018 Mar 24.
72. Kisiel B, etal., Clin Endocrinol (Oxf). 2008 Mar;68(3):429-34. Epub 2007 Oct 17.
73. Kisiel BM, etal., Lupus. 2011 Jan;20(1):85-9. Epub 2010 Oct 20.
74. Kong LN, etal., Acta Pharmacol Sin. 2005 Jun;26(6):666-72.
75. Krege JH, etal., Proc Natl Acad Sci U S A 1998 Dec 22;95(26):15677-82.
76. Kudwa AE, etal., Physiol Behav. 2014 Apr 22;129:287-96. doi: 10.1016/j.physbeh.2014.03.004. Epub 2014 Mar 13.
77. Kuiper GG, etal., Endocrinology. 1997 Mar;138(3):863-70.
78. Kuiper GG, etal., Proc Natl Acad Sci U S A 1996 Jun 11;93(12):5925-30.
79. Kulakosky PC, etal., J Mol Endocrinol. 2002 Aug;29(1):137-52.
80. Kung AW, etal., Bone. 2006 Nov;39(5):1097-106. Epub 2006 Jun 13.
81. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
82. Larsson K, etal., Clin Exp Rheumatol. 2006 Mar-Apr;24(2 Suppl 41):S17-9.
83. Le Saux M, etal., Neuropharmacology. 2006 Mar;50(4):451-7. Epub 2005 Nov 23.
84. Leventhal L, etal., Eur J Pharmacol. 2006 Dec 28;553(1-3):146-8. Epub 2006 Sep 26.
85. Li J and McMurray RW, Clin Immunol. 2007 May;123(2):219-26. Epub 2007 Mar 1.
86. Li L, etal., Pain. 2009 May;143(1-2):37-40. doi: 10.1016/j.pain.2009.01.005. Epub 2009 Mar 13.
87. Liang YQ, etal., Int J Obes Relat Metab Disord. 2002 Aug;26(8):1103-9.
88. Looijer-van Langen M, etal., Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G621-6. Epub 2011 Jan 20.
89. Lucas TF, etal., Biol Reprod. 2008 Jan;78(1):101-14. Epub 2007 Oct 10.
90. Lucas TF, etal., Mol Cell Endocrinol. 2013 Sep 18. pii: S0303-7207(13)00377-8. doi: 10.1016/j.mce.2013.09.015.
91. Luckhaus C, etal., Alzheimer Dis Assoc Disord. 2006 Oct-Dec;20(4):322-3.
92. Lund TD, etal., Endocrinology. 2005 Feb;146(2):797-807. Epub 2004 Oct 28.
93. Mabuchi F, etal., Am J Ophthalmol. 2010 May;149(5):826-30.e1-2. doi: 10.1016/j.ajo.2009.12.030.
94. Madeira M, etal., BMC Cancer. 2013 Sep 18;13:425. doi: 10.1186/1471-2407-13-425.
95. Madinier A, etal., Behav Brain Res. 2014 Mar 15;261:282-8. doi: 10.1016/j.bbr.2013.12.046. Epub 2014 Jan 6.
96. Maguire P, etal., Breast Cancer Res Treat. 2005 Nov;94(2):145-52.
97. Mandal A, etal., Mol Cell Biochem. 2013 Sep 29.
98. Mansur Ade P, etal., Arch Med Res. 2005 Sep-Oct;36(5):511-7.
99. Maruyama A, etal., Hypertens Res. 2004 Dec;27(12):903-9.
100. Maruyama K, etal., Biochem Biophys Res Commun 1998 May 8;246(1):142-7.
101. Massinen S, etal., Hum Mol Genet. 2009 Aug 1;18(15):2802-12. doi: 10.1093/hmg/ddp215. Epub 2009 May 7.
102. McGregor C, etal., Endocrinology. 2014 Jul;155(7):2480-91. doi: 10.1210/en.2013-1976. Epub 2014 May 13.
103. McPherson SJ, etal., Endocrinology. 2007 Feb;148(2):566-74. Epub 2006 Oct 26.
104. Mehra RD, etal., Brain Res. 2005 Sep 14;1056(1):22-35.
105. Meltser I, etal., J Clin Invest. 2008 Apr;118(4):1563-70. doi: 10.1172/JCI32796.
106. Mendoza N, etal., Climacteric. 2012 Dec;15(6):587-93. doi: 10.3109/13697137.2012.656160. Epub 2012 Feb 15.
107. Merchenthaler I Neuropeptides. 2005 Jun;39(3):341-3.
108. Merchenthaler I, etal., Endocrinology. 2005 Jun;146(6):2760-5. Epub 2005 Mar 24.
109. MGD data from the GO Consortium
110. Miller WJ, etal., J Neurosci. 2004 Nov 24;24(47):10628-35.
111. Moron FJ, etal., Bone. 2006 Jul;39(1):213-21. Epub 2006 Mar 10.
112. Nancy P and Berrih-Aknin S, Endocrinology. 2005 May;146(5):2345-53. Epub 2005 Jan 20.
113. NCBI rat LocusLink and RefSeq merged data July 26, 2002
114. NO_AUTHOR Int J Cancer. 2010 Jun 15;126(12):2935-46. doi: 10.1002/ijc.24892.
115. Nonni A, etal., Virchows Arch. 2007 Nov;451(5):893-7. Epub 2007 Oct 9.
116. Nordmeyer J, etal., Circulation. 2004 Nov 16;110(20):3270-5. Epub 2004 Nov 8.
117. Ogawa S, etal., J Hum Genet. 2000;45(6):327-30.
118. Orihuela PA, etal., Reprod Biol Endocrinol. 2009 Nov 30;7:139.
119. Orikasa C and Sakuma Y, J Neuroendocrinol. 2004 Dec;16(12):964-9.
120. Orikasa C, etal., Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3306-11. Epub 2002 Feb 19.
121. Pathak S, etal., Mol Cell Endocrinol. 2010 Jan 15;314(1):110-7. doi: 10.1016/j.mce.2009.08.005. Epub 2009 Aug 14.
122. Patisaul HB, etal., PLoS One. 2012;7(9):e43890. doi: 10.1371/journal.pone.0043890. Epub 2012 Sep 5.
123. Peter I, etal., Am J Hypertens. 2005 Nov;18(11):1388-95.
124. Pirskanen M, etal., Eur J Hum Genet. 2005 Sep;13(9):1000-6.
125. Potier M, etal., Am J Pathol. 2002 May;160(5):1877-85.
126. Prins GS, etal., Endocrinology. 1998 Mar;139(3):874-83.
127. Qiu C, etal., Carcinogenesis. 2005 Apr;26(4):763-9. Epub 2005 Jan 6.
128. Racine Miousse I, etal., Physiol Genomics. 2013 Sep 17.
129. Raju J, etal., J Nutr. 2009 Mar;139(3):474-81. doi: 10.3945/jn.108.099200. Epub 2009 Jan 13.
130. Raval AP, etal., PLoS One. 2013 Apr 12;8(4):e60716. doi: 10.1371/journal.pone.0060716. Print 2013.
131. Redler S, etal., Exp Dermatol. 2012 May;21(5):390-3. doi: 10.1111/j.1600-0625.2012.01469.x.
132. Revankar CM, etal., Science. 2005 Mar 11;307(5715):1625-30. Epub 2005 Feb 10.
133. Rezg R, etal., Environ Int. 2014 Mar;64C:83-90. doi: 10.1016/j.envint.2013.12.007. Epub 2013 Dec 29.
134. RGD automated data pipeline
135. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
136. RGD automated import pipeline for gene-chemical interactions
137. Rissman EF, etal., Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3996-4001. Epub 2002 Mar 12.
138. Rivadeneira F, etal., J Bone Miner Res. 2006 Sep;21(9):1443-56.
139. Rosa FE, etal., Hum Pathol. 2008 Jan 29;.
140. Rumi MAK, etal., Endocrinology. 2017 Jul 1;158(7):2330-2343. doi: 10.1210/en.2016-1916.
141. Saijo K, etal., Cell. 2011 May 13;145(4):584-95.
142. Salian-Mehta S, etal., J Appl Toxicol. 2013 Apr 26. doi: 10.1002/jat.2882.
143. Sar M and Welsch F, Endocrinology. 1999 Feb;140(2):963-71.
144. Sato H, etal., Rheumatol Int. 2011 Apr 27.
145. Shao R, etal., Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E147-58. Epub 2007 Mar 20.
146. Sharawy N, etal., Microvasc Res. 2013 Jan;85:118-27. doi: 10.1016/j.mvr.2012.10.002. Epub 2012 Oct 11.
147. Shen K, etal., Biochem Pharmacol. 2014 Mar 1;88(1):66-74. doi: 10.1016/j.bcp.2014.01.007. Epub 2014 Jan 16.
148. Shim GJ, etal., Proc Natl Acad Sci U S A 2003 May 27;100(11):6694-9. Epub 2003 May 9.
149. Shirai M, etal., Int J Impot Res. 2003 Dec;15(6):391-6.
150. Simonoska R, etal., J Endocrinol. 2009 Jun;201(3):397-406. doi: 10.1677/JOE-09-0060. Epub 2009 Mar 17.
151. Smith JA, etal., Neurochem Res. 2011 Sep;36(9):1587-93. Epub 2010 Dec 3.
152. Somponpun SJ and Sladek CD, J Neuroendocrinol. 2004 Jun;16(6):544-9.
153. Somponpun SJ and Sladek CD, J Neurosci. 2003 May 15;23(10):4261-9.
154. Sonestedt E, etal., J Nutr. 2009 May;139(5):993-1001. doi: 10.3945/jn.108.101691. Epub 2009 Mar 25.
155. Staub C, etal., Biol Reprod. 2005 Oct;73(4):703-12. Epub 2005 Jun 8.
156. Stedronsky K, etal., J Neuroendocrinol. 2002 Jun;14(6):472-85.
157. Sun J, etal., J Cardiovasc Pharmacol. 2011 Oct;58(4):399-405.
158. Suzuki S and Handa RJ, Endocrinology. 2004 Aug;145(8):3658-70. Epub 2004 Apr 15.
159. Takagi K, etal., Acta Med Okayama. 2007 Oct;61(5):283-98.
160. Taylor AH, etal., Br J Dermatol. 2008 Feb;158(2):319-28. Epub 2007 Dec 11.
161. Treeck O, etal., J Steroid Biochem Mol Biol. 2009 Apr;114(3-5):207-11. doi: 10.1016/j.jsbmb.2009.02.012. Epub 2009 Mar 3.
162. Tsezou A, etal., Breast. 2008 Apr;17(2):159-66. Epub 2007 Sep 29.
163. Umar S, etal., Am J Respir Crit Care Med. 2011 Jun 23.
164. Vaillant C, etal., Endocrinology 2002 Nov;143(11):4249-58.
165. Vallejo G, etal., Mol Endocrinol. 2005 Dec;19(12):3023-37. Epub 2005 Jul 14.
166. Vodstrcil LA, etal., Biol Reprod. 2010 Nov;83(5):825-32. doi: 10.1095/biolreprod.110.084301. Epub 2010 Aug 4.
167. Wang J, etal., Lupus. 2010 May;19(6):734-40. Epub 2010 Mar 19.
168. Wang JQ, etal., Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2013 Feb;35(1):58-63. doi: 10.3881/j.issn.1000-503X.2013.01.011.
169. Wang L, etal., Proc Natl Acad Sci U S A 2003 Jan 21;100(2):703-8. Epub 2003 Jan 6.
170. Wang M, etal., Breast Cancer Res Treat. 2009 May;115(1):213-20. doi: 10.1007/s10549-008-0062-x. Epub 2008 May 31.
171. Wang M, etal., Surgery. 2008 Aug;144(2):233-8. Epub 2008 May 9.
172. Weigt C, etal., Mol Cell Endocrinol. 2012 Apr 4;351(2):227-38. doi: 10.1016/j.mce.2011.12.013. Epub 2011 Dec 30.
173. Weihua Z, etal., Proc Natl Acad Sci U S A 2001 May 22;98(11):6330-5.
174. Weihua Z, etal., Proc Natl Acad Sci U S A 2002 Oct 15;99(21):13589-94.
175. Westberg L, etal., Psychoneuroendocrinology. 2004 Sep;29(8):993-8.
176. Wise BL, etal., J Rheumatol. 2009 Dec;36(12):2772-9. doi: 10.3899/jrheum.081208. Epub 2009 Nov 2.
177. Witkowska HE, etal., Steroids. 1997 Aug-Sep;62(8-9):621-31.
178. Xiang Q, etal., Pharmacology. 2010;86(2):117-24. doi: 10.1159/000315065. Epub 2010 Aug 6.
179. Xue B, etal., Hypertension. 2013 Jun;61(6):1255-62. doi: 10.1161/HYPERTENSIONAHA.111.00903. Epub 2013 Apr 22.
180. Yaffe K, etal., Neurobiol Aging. 2009 Apr;30(4):607-14. Epub 2007 Sep 21.
181. Yang F, etal., Neuroreport. 2014 Jan 22;25(2):100-4. doi: 10.1097/WNR.0000000000000052.
182. Yang GS, etal., Chin Med J (Engl). 2007 Sep 20;120(18):1611-5.
183. Yang SH, etal., Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4130-5. Epub 2004 Mar 15.
184. Yip L, etal., Br J Dermatol. 2012 May;166(5):1131-4. doi: 10.1111/j.1365-2133.2011.10702.x. Epub 2012 Mar 5.
185. Zhai G, etal., PLoS One. 2013 May 21;8(5):e64445. doi: 10.1371/journal.pone.0064445. Print 2013.
186. Zhai YK, etal., Zhongguo Zhong Yao Za Zhi. 2013 Jan;38(1):105-11.
187. Zhang Y, etal., Toxicol Lett. 2013 Sep 23. pii: S0378-4274(13)01325-8. doi: 10.1016/j.toxlet.2013.09.011.
188. Zhao L, etal., Brain Res. 2004 Jun 4;1010(1-2):22-34.
189. Zheng SL, etal., Cancer Res. 2003 Nov 15;63(22):7624-9.
190. Zheng Y, etal., PLoS One. 2012;7(7):e40494. doi: 10.1371/journal.pone.0040494. Epub 2012 Jul 11.
191. Zheng YJ, etal., Zhonghua Nei Ke Za Zhi. 2010 Apr;49(4):309-12.
192. Zhu Y, etal., Science 2002 Jan 18;295(5554):505-8.
Additional References at PubMed
PMID:9058381   PMID:9492041   PMID:9671811   PMID:9697695   PMID:10648597   PMID:10681512   PMID:10731636   PMID:10976058   PMID:11181953   PMID:11739747   PMID:11818503   PMID:11825673  
PMID:11882461   PMID:11932206   PMID:12021182   PMID:12039952   PMID:12115890   PMID:12161009   PMID:12372009   PMID:12393262   PMID:12444070   PMID:12697694   PMID:12798205   PMID:12801993  
PMID:12856802   PMID:12867731   PMID:12933691   PMID:14502087   PMID:14552897   PMID:14604844   PMID:14613904   PMID:14614214   PMID:14644637   PMID:15112577   PMID:15187231   PMID:15215204  
PMID:15219413   PMID:15236331   PMID:15261305   PMID:15278948   PMID:15280152   PMID:15344311   PMID:15345745   PMID:15474102   PMID:15579769   PMID:15862946   PMID:15862953   PMID:15935066  
PMID:15994024   PMID:16443195   PMID:16648639   PMID:16758356   PMID:17026970   PMID:17045976   PMID:17237237   PMID:17480015   PMID:17490623   PMID:17493623   PMID:17537544   PMID:17698719  
PMID:17850458   PMID:17947358   PMID:18056768   PMID:18067893   PMID:18097519   PMID:18174277   PMID:18246095   PMID:18297067   PMID:18308321   PMID:18342348   PMID:18433985   PMID:18464259  
PMID:18492815   PMID:18511514   PMID:18617618   PMID:18627487   PMID:18701637   PMID:18709647   PMID:18753331   PMID:18805896   PMID:19022902   PMID:19057146   PMID:19094096   PMID:19126643  
PMID:19189968   PMID:19309532   PMID:19420389   PMID:19429457   PMID:19559077   PMID:19583861   PMID:19698287   PMID:19922658   PMID:19953342   PMID:20068009   PMID:20074560   PMID:20085801  
PMID:20096765   PMID:20136693   PMID:20138435   PMID:20160663   PMID:20347696   PMID:20381466   PMID:20424134   PMID:20460386   PMID:20554652   PMID:20584107   PMID:20702577   PMID:20810711  
PMID:20875808   PMID:20926581   PMID:20926671   PMID:20969598   PMID:21182203   PMID:21243777   PMID:21311134   PMID:21392135   PMID:21484804   PMID:21606911   PMID:21628965   PMID:21774811  
PMID:21777515   PMID:21782536   PMID:21808025   PMID:21884022   PMID:21951318   PMID:21972199   PMID:21981044   PMID:21981076   PMID:21995903   PMID:22142178   PMID:22152882   PMID:22169964  
PMID:22192617   PMID:22248091   PMID:22278942   PMID:22330348   PMID:22366496   PMID:22428062   PMID:22541803   PMID:22562172   PMID:22713467   PMID:22778216   PMID:23020785   PMID:23515287  
PMID:23515288   PMID:23749762   PMID:23911387   PMID:24033289   PMID:24188094   PMID:24347325   PMID:24352099   PMID:24390426   PMID:24718039   PMID:25211590   PMID:25217305   PMID:25486578  
PMID:25612677   PMID:25869617   PMID:26408543   PMID:26440063   PMID:26987957   PMID:27004961   PMID:27130032   PMID:27182159   PMID:27321970   PMID:27594441   PMID:27832635   PMID:28362134  
PMID:28542730   PMID:28863192   PMID:28919414   PMID:29030963   PMID:29127073   PMID:29261182   PMID:29394091   PMID:29421437   PMID:30113650   PMID:30277501   PMID:30296306   PMID:30447304  
PMID:30731078   PMID:30790128   PMID:30887585   PMID:31115535   PMID:31250245   PMID:31708494   PMID:31877966   PMID:31931041  


Genomics

Candidate Gene Status
Esr2 is a candidate Gene for QTL Schws8
Comparative Map Data
Esr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2694,858,438 - 94,909,630 (-)NCBI
Rnor_6.0 Ensembl699,164,357 - 99,214,251 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0699,163,953 - 99,214,711 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06108,576,398 - 108,626,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4698,691,167 - 98,775,299 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1698,694,622 - 98,778,755 (-)NCBI
Celera693,284,596 - 93,334,744 (-)NCBICelera
RH 3.4 Map6686.1RGD
Cytogenetic Map6q24NCBI
ESR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1464,084,232 - 64,338,112 (-)EnsemblGRCh38hg38GRCh38
GRCh381464,226,707 - 64,338,631 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371464,693,425 - 64,805,331 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361463,763,504 - 63,875,021 (-)NCBINCBI36hg18NCBI36
Build 341463,769,607 - 63,830,831NCBI
Celera1444,751,460 - 44,862,976 (-)NCBI
Cytogenetic Map14q23.2-q23.3NCBI
HuRef1444,866,333 - 44,977,880 (-)NCBIHuRef
CHM1_11464,633,252 - 64,745,077 (-)NCBICHM1_1
Esr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391276,167,193 - 76,224,033 (-)NCBIGRCm39mm39
GRCm39 Ensembl1276,167,193 - 76,224,033 (-)Ensembl
GRCm381276,120,419 - 76,177,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1276,120,419 - 76,177,259 (-)EnsemblGRCm38mm10GRCm38
MGSCv371277,221,406 - 77,278,246 (-)NCBIGRCm37mm9NCBIm37
MGSCv361277,039,259 - 77,096,099 (-)NCBImm8
Celera1277,215,189 - 77,271,340 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1233.52NCBI
Esr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554665,575,088 - 5,638,946 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554665,587,003 - 5,644,765 (+)NCBIChiLan1.0ChiLan1.0
ESR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11463,064,397 - 63,175,303 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1463,064,402 - 63,131,303 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01444,807,875 - 44,919,780 (-)NCBIMhudiblu_PPA_v0panPan3
ESR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1838,645,917 - 38,715,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl838,645,430 - 38,702,691 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha838,338,303 - 38,407,225 (-)NCBI
ROS_Cfam_1.0838,869,013 - 38,937,387 (-)NCBI
UMICH_Zoey_3.1838,489,186 - 38,557,866 (-)NCBI
UNSW_CanFamBas_1.0838,561,325 - 38,629,870 (-)NCBI
UU_Cfam_GSD_1.0838,921,461 - 38,990,144 (-)NCBI
Esr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864066,173,041 - 66,235,531 (+)NCBI
SpeTri2.0NW_0049364957,956,168 - 8,018,356 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1193,722,164 - 193,906,565 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11193,823,666 - 193,907,330 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,715,909 - 215,788,512 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESR2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12441,426,333 - 41,513,802 (-)NCBI
ChlSab1.1 Ensembl2441,447,224 - 41,512,486 (-)Ensembl
Esr2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473436,742,913 - 36,862,993 (+)NCBI

Position Markers
D6Rat87  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0699,182,033 - 99,182,221NCBIRnor6.0
Rnor_5.06108,593,793 - 108,593,981UniSTSRnor5.0
RGSC_v3.4698,742,973 - 98,743,161UniSTSRGSC3.4
RGSC_v3.4698,742,972 - 98,743,161RGDRGSC3.4
RGSC_v3.1698,746,429 - 98,746,617RGD
Celera693,302,793 - 93,302,965UniSTS
RH 3.4 Map6677.0RGD
RH 3.4 Map6677.0UniSTS
SHRSP x BN Map656.7498UniSTS
SHRSP x BN Map656.7498RGD
FHH x ACI Map668.02RGD
Cytogenetic Map6q24UniSTS
RH94710  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0699,164,641 - 99,164,816NCBIRnor6.0
Rnor_5.06108,576,715 - 108,576,890UniSTSRnor5.0
RGSC_v3.4698,691,449 - 98,691,624UniSTSRGSC3.4
Celera693,284,878 - 93,285,053UniSTS
RH 3.4 Map6686.1UniSTS
Cytogenetic Map6q24UniSTS
Esr2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0699,203,253 - 99,204,581NCBIRnor6.0
Rnor_5.06108,615,013 - 108,616,341UniSTSRnor5.0
RGSC_v3.4698,764,193 - 98,765,521UniSTSRGSC3.4
Celera693,323,998 - 93,325,324UniSTS
Cytogenetic Map6q24UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)62537030111715717Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)67009971115379601Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)648432758108268790Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)660606431108154445Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)660606431108154445Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)662263348107263348Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)666129520111129520Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)671206251116206251Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)675449871120449871Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)675623277120276465Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)675623277120623277Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)675623277136143011Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)675623277136426962Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)675623393136142742Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)675623393136142742Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)676902247114203334Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)684763275108464097Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)684763275108464097Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)686422697115379601Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)687418448111129520Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)688507712133507712Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)688996335139410483Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)689631358134631358Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)689631358134631358Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)691703409136703409Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (VE) (CMO:0000132)692879510137879510Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)693706176111134673Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)697949772133849286Rat


Genetic Models
This gene Esr2 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:912
Count of miRNA genes:211
Interacting mature miRNAs:256
Transcripts:ENSRNOT00000007109, ENSRNOT00000041872, ENSRNOT00000042682, ENSRNOT00000043602
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2
Low 6 7 26 18 1
Below cutoff 3 18 7 4 10 4 5 5 34 19 14 10 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB012721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB190769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB190770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB530987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF042058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF042059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF042060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF042061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF161187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ002602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ002603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000007109   ⟹   ENSRNOP00000007109
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl699,164,875 - 99,204,590 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000041872   ⟹   ENSRNOP00000041339
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl699,164,875 - 99,204,590 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000042682   ⟹   ENSRNOP00000040505
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl699,164,357 - 99,214,251 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000043602   ⟹   ENSRNOP00000043144
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl699,164,590 - 99,204,825 (-)Ensembl
RefSeq Acc Id: NM_012754   ⟹   NP_036886
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2694,858,894 - 94,908,919 (-)NCBI
Rnor_6.0699,164,359 - 99,214,116 (-)NCBI
Rnor_5.06108,576,398 - 108,626,196 (-)NCBI
RGSC_v3.4698,691,167 - 98,775,299 (-)RGD
Celera693,284,596 - 93,334,744 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240221   ⟹   XP_006240283
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2694,858,438 - 94,909,630 (-)NCBI
Rnor_6.0699,163,953 - 99,214,710 (-)NCBI
Rnor_5.06108,576,398 - 108,626,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594038   ⟹   XP_017449527
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0699,165,133 - 99,214,711 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594039   ⟹   XP_017449528
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0699,165,133 - 99,214,711 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594040   ⟹   XP_017449529
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0699,165,133 - 99,214,711 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594041   ⟹   XP_017449530
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0699,163,953 - 99,214,710 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594042   ⟹   XP_017449531
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0699,163,953 - 99,214,710 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_036886   ⟸   NM_012754
- Sequence:
RefSeq Acc Id: XP_006240283   ⟸   XM_006240221
- Peptide Label: isoform X1
- UniProtKB: Q59IV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449531   ⟸   XM_017594042
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017449530   ⟸   XM_017594041
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017449529   ⟸   XM_017594040
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017449528   ⟸   XM_017594039
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017449527   ⟸   XM_017594038
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000043144   ⟸   ENSRNOT00000043602
RefSeq Acc Id: ENSRNOP00000041339   ⟸   ENSRNOT00000041872
RefSeq Acc Id: ENSRNOP00000007109   ⟸   ENSRNOT00000007109
RefSeq Acc Id: ENSRNOP00000040505   ⟸   ENSRNOT00000042682
Protein Domains
NR LBD   Nuclear receptor

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)