Strain Report - Rat Genome Database

Name: LE- Arid1b em1Mcwi
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: LE-Arid1b^em1Mcwi

Symbol:

LE-Arid1b^em1Mcwi

Strain:

LE-Arid1b^em1

Substrain:

Mcwi

RGD ID:

14394518

Citation ID:

RRID:RGD_14394518

Ontology ID:

RS:0004695

Alleles:

Arid1b^em1Mcwi

Type:

mutant

Source:

Generated with support from the Simons Foundation Autism Research Initiative (SFARI); MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu

Origin:

CRISPR/Cas9 system was used to introduce a mutation in the Arid1b gene of Crl:LE rat embryos. The resulting mutation is deletion of exon 4.

Last Known Status:

Live Animals; Cryopreserved Sperm (as of 2021-11-03)

Research Usage

Autism, ADHD, Developmental delay, Intellectual disability, Epilepsy (from SFARI GENE)

Genotyping Protocol

Download Genotyping Protocol

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	45,567,991 - 45,923,644	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	1	46,130,110 - 46,131,244	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	1	47,197,399 - 47,550,032	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	1	40,012,872 - 40,324,266	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

References

References - curated

#	Reference Title	Reference Citation
1.	Data registered by Dr. Melinda Dwinell’s group	Personal communication between Dr. Melinda Dwinell’s group and the RGD curators

Region

Allelic Variants

Name	Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Assembly
Arid1bem1Mcwi-var1	chr1	46130110	46131244	CCAAGCCTATAGTTGCTCACTTTATTGAAGTCTTCTTGTAGGACTTCATGTAGCCCCATGGACCCATCGCCTGCCTCAGAATGGCAGTGCTAGGGGCCACATGGCAGCTCCCTCGCCTGTTCTTTCCCAGAATCTTCTCTCTGCTGGTTCAGCTGTTCTCTCTCTGTTTTATCATTTATTAAAGAGTTTTATTTGTTATATTTTAGCATTTATGTGGACGACTGCTTACTCCATTCCAGTGGTAACTTGCTAAGCCGAGTGCTGCCTGACAGAACATTTGAATAGGCGCACGGCTGGGTGGCAGAAGGGGAGCCTTCAAGTCATTTGTGAGTGCAAGGTGCAGCTTGCCTCATGTTTAGTTGATGCCAAGCCTGCTGTGTGAGTTTGCTGGAGTCTAGTGAGAAGTGGCCACTCCAAGTCTCGGTCTTACCCATCCACACTGTCTCTGAAGGAGTGACACTGTGGCTTTCAAACCATGTTTCCTGTACTTGCTGTCCACGTGTATGAACACCCGCTTTCTCTTTCTTCCTCAGGACCTGTCTGGCTCCATCGATGATCTCCCCACGGGAACAGAAGCAACTCTGAGCTCAGCGGTCAGTGCGTCCGGGTCTACGAGCAGCCAGGGGGATCAGAGCAACCCAGCTCAGTCTCCTTTCTCCCCACATGCATCACCCCACCTCTCCAGCATCCCCGGAGGGCCGTCACCTTCTCCTGTTGGCTCTCCTGTGGGCAGCAACCAGTCGAGGTCTGGCCCAATCTCCCCTGCGAGTATACCAGGTACTGCCATGCCTACTGGTCCCACCCACCCCACCCCACCTCGCCCCGTGTGAAGACAGGTGTCTCCAGAGCAGCTCACACTCTGCCTTCCTAGGCACTGTTTACTCCGCAAAACCATGAATACGATTGCATATTGGGGCTGTAACAGAGTTCCCTGACAAACATATGAGGGTCCAGTTTCATAAGAGTCGACAAATGAATGATCAATGCCCAACTACTTTAGACGAGACAGCTACTTTCAAATGTTCAGTTTGCCAGAAACAAACCCCTTCCCTGACTCCTGTCTTGTAATCGTCCTGTAGTGAGGACCCTTCATCAATATATGTCCTGAAGATGAAACTGCTGACGAGTGTCGCCC	-	deletion	Rnor_6.0

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: LE-Arid1bem1Mcwi

Strain: LE-Arid1b^em1Mcwi