Gene: Grm5 (glutamate metabotropic receptor 5) Rattus norvegicus
Symbol: Grm5
Name: glutamate metabotropic receptor 5
Description: ENCODES a protein that exhibits A2A adenosine receptor binding; glutamate receptor activity; protein tyrosine kinase binding; INVOLVED IN activation of MAPKKK activity; chemical synaptic transmission; desensitization of G-protein coupled receptor protein signaling pathway; PARTICIPATES IN calcium/calcium-mediated signaling pathway; glutamate signaling pathway; Huntington disease pathway; ASSOCIATED WITH Attention Deficit Disorder with Hyperactivity (ortholog); Cocaine-Related Disorders (ortholog); Diabetic Neuropathies (ortholog); FOUND IN astrocyte projection; dendritic shaft; dendritic spine; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-3,5-dihydroxyphenylglycine
Type: protein-coding
Also known as: glutamate receptor, metabotropic 5; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; mGlur5
Homo sapiens (human) : GRM5 (glutamate metabotropic receptor 5)  HGNC  Alliance
Mus musculus (house mouse) : Grm5 (glutamate receptor, metabotropic 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm5 (glutamate metabotropic receptor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM5 (glutamate metabotropic receptor 5)
Canis lupus familiaris (dog) : GRM5 (glutamate metabotropic receptor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm5 (glutamate metabotropic receptor 5)
more info ...
Allele / Splice: Grm5em1Sage  
Genetic Models: SD-Grm5em1Sage
Is Marker For: Strains:   FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01151,207,846 - 151,785,038 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01157,517,676 - 158,096,869 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41143,857,225 - 144,477,419 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11143,935,630 - 144,555,825 (+)NCBI
Celera1139,643,467 - 140,193,665 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Grm5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2746
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE