Strain: F344-Ttnem2Sage

Symbol: F344-Ttnem2Sage
Strain: F344-Ttnem2
Substrain: Sage
Ontology ID: RS:0004303
Alleles: Ttnem2Sage
Also known as: TTNtvZ rat
Type: mutant
Source: Duke-National University of Singapore, Singapore
Origin: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Ttn into F344 embryos. The zinc-finger nuclease mediated genome editing system created a deletion of exons 2-6 (5,286-bp deletion, coordinates 2,323-7,608) to introduce a frameshift (Rnor_5.0).
Last Known Status: Unknown (as of 2016-11-28)
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0363,565,160 - 63,837,815RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0370,138,896 - 70,408,647RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4359,404,023 - 59,665,308RGD_MAPPER_PIPELINERGSC3.4

Phenotype Annotations
Experimental Data Annotations
References - curated
RGD Disease Portals


Additional Information

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Strain Registration

RGD Object Information
RGD ID: 11565829
Created: 2016-11-28
Species: Rattus norvegicus
Last Modified: 2016-11-28
Status: ACTIVE