Gene: Plekha7 (pleckstrin homology domain containing A7) Rattus norvegicus
Symbol: Plekha7
Name: pleckstrin homology domain containing A7
Description: ENCODES a protein that exhibits delta-catenin binding (ortholog); INVOLVED IN epithelial cell-cell adhesion (ortholog); zonula adherens maintenance (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH decreased susceptibility to hypertension; decreased systemic vascular resistance; decreased urine albumin level; ASSOCIATED WITH Cardiac Fibrosis; Glomerulosclerosis; Glaucoma, Angle-Closure (ortholog); FOUND IN cell junction (ortholog); centrosome (ortholog); cytosol (ortholog); INTERACTS WITH bisphenol A; vinclozolin; (-)-epigallocatechin 3-gallate (ortholog)
Type: protein-coding
Also known as: LOC499249; pleckstrin homology domain containing, family A member 7; pleckstrin homology domain-containing family A member 7; RGD1304650; similar to Plekha7 protein
Homo sapiens (human) : PLEKHA7 (pleckstrin homology domain containing A7)  HGNC  AGR
Mus musculus (house mouse) : Plekha7 (pleckstrin homology domain containing, family A member 7)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Plekha7 (pleckstrin homology domain containing A7)
Pan paniscus (bonobo/pygmy chimpanzee) : PLEKHA7 (pleckstrin homology domain containing A7)
Canis lupus familiaris (dog) : PLEKHA7 (pleckstrin homology domain containing A7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plekha7 (pleckstrin homology domain containing A7)
more info ...
Allele / Splice: Plekha7em1Mcwi   Plekha7em4Mcwi  
Genetic Models: SS-Plekha7em4Mcwi SS-Plekha7em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01185,427,600 - 185,493,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01192,397,589 - 192,463,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,249,022 - 174,316,226 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1168,231,482 - 168,298,068 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Plekha7
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1598216
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE