Nr1i2 (nuclear receptor subfamily 1, group I, member 2)

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Gene: Nr1i2 (nuclear receptor subfamily 1, group I, member 2) Rattus norvegicus

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Symbol:

Nr1i2

Name:

nuclear receptor subfamily 1, group I, member 2

RGD ID:

69057

Description:

Enables nuclear receptor activity. Predicted to be involved in several processes, including cellular response to type I interferon; regulation of transcription by RNA polymerase II; and xenobiotic transport. Predicted to act upstream of or within negative regulation of DNA-templated transcription and positive regulation of gene expression. Predicted to be located in intermediate filament cytoskeleton and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Biomarker of cholestasis and epilepsy. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2); INTERACTS WITH (+)-schisandrin B; (+)-trans-(S)-allethrin; (3-phenoxyphenyl)methanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC108643; nuclear receptor subfamily 1 group I member 2; nuclear receptor subfamily 1, group 1, member 2; orphan nuclear receptor PXR; pregnane X receptor (nuclear receptor sub family 1, group I, member 2); PXR

RGD Orthologs

Alliance Orthologs

More Info

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Allele / Splice:

Nr1i2^em1Sage

Genetic Models:

SD-Nr1i2^em1Sage SD-Nr1i2^em1Sage Nr1i3^em1Sage SD-Nr1i2^em1Sage Nr1i3^em1Sage Ahr^em1Sage

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	75,965,717 - 76,006,733 (+)	NCBI		GRCr8
mRatBN7.2	11	62,460,213 - 62,496,665 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	62,460,213 - 62,496,658 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	71,272,711 - 71,309,163 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	63,934,940 - 63,971,386 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	62,985,406 - 63,021,853 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	65,022,100 - 65,058,546 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	65,022,100 - 65,058,545 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	67,024,185 - 67,060,494 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	64,239,918 - 64,276,702 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	64,297,534 - 64,333,716 (+)	NCBI
Celera	11	61,960,674 - 61,997,009 (+)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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