Gene: Esr1 (estrogen receptor 1) Rattus norvegicus
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Symbol: Esr1
Name: estrogen receptor 1
Description: ENCODES a protein that exhibits DNA binding; enzyme binding; estrogen receptor activity; INVOLVED IN baculum development; cellular response to estradiol stimulus; decidualization; PARTICIPATES IN estrogen signaling pathway; insulin-like growth factor signaling pathway; bisphenol A response pathway; ASSOCIATED WITH abnormal body size; abnormal female reproductive system morphology; abnormal male reproductive system morphology; ASSOCIATED WITH cryptorchidism; Diabetes Mellitus, Experimental ; Diabetic Nephropathies; FOUND IN cytoplasm; mitochondrion; neuron projection; INTERACTS WITH (+)-alpha-tocopherol; (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane
AGR Description: Exhibits several functions, including DNA binding activity, enzyme binding activity, and estrogen receptor activity; involved in several processes, including animal organ development, cellular response to hormone stimulus, and positive regulation of signal transduction; localizes to several cellular components, including the T-tubule, cytoplasm, and intracellular membrane-bounded organelle; used to study several diseases, including infertility, obesity, peritonitis, pleurisy, and prostate disease (multiple); biomarker of cryptorchidism, osteoporosis, and ovarian cancer; orthologous to human ESR1 (estrogen receptor 1).
Merged Description: Exhibits several functions, including DNA binding activity, enzyme binding activity, and estrogen receptor activity; involved in several processes, including animal organ development, cellular response to hormone stimulus, and positive regulation of signal transduction; localizes to several cellular components, including the T-tubule, cytoplasm, and intracellular membrane-bounded organelle; used to study several diseases, including infertility, obesity, peritonitis, pleurisy, and prostate disease (multiple); biomarker of cryptorchidism, osteoporosis, and ovarian cancer; orthologous to human ESR1 (estrogen receptor 1); PARTICIPATES IN estrogen signaling pathway; insulin-like growth factor signaling pathway; bisphenol A response pathway; INTERACTS WITH (+)-alpha-tocopherol; (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-terminally-truncated estrogen receptor alpha product-1; Er alpha; ER-alpha; Esr; estradiol receptor; estrogen receptor; estrogen receptor 1 (alpha); Estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha i45aL; estrogen receptor alpha i45aS; estrogen receptor alpha i45c; estrogen receptor alpha i56a; estrogen receptor alpha i56b; estrogen receptor alpha i56c; estrogen receptor alpha i56dL; estrogen receptor alpha i56dS; estrogen receptor alpha i56e; estrogen receptor alpha variant delta 4; nuclear receptor subfamily 3 group A member 1; RNESTROR; truncated estrogen receptor product-2; trunctaed estrogen receptor product-1
Orthologs:
Homo sapiens (human) : ESR1 (estrogen receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Esr1 (estrogen receptor 1 (alpha))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Esr1 (estrogen receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ESR1 (estrogen receptor 1)
Canis lupus familiaris (dog) : ESR1 (estrogen receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Esr1 (estrogen receptor 1)
Sus scrofa (pig) : ESR1 (estrogen receptor 1)
more info ...
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0141,192,029 - 41,594,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0142,534,049 - 42,935,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4135,523,680 - 35,759,891 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1135,526,624 - 35,762,826NCBI
Celera136,921,417 - 37,175,762 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model