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Gene: Syne1 (spectrin repeat containing nuclear envelope protein 1) Rattus norvegicus
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Symbol: Syne1
Name: spectrin repeat containing nuclear envelope protein 1
Description: Exhibits enzyme binding activity and signaling receptor binding activity. Involved in several processes, including negative regulation of mini excitatory postsynaptic potential; nervous system development; and regulation of receptor-mediated endocytosis. Localizes to several cellular components, including the dendritic spine head; midbody; and nuclear membrane. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 4; autosomal recessive cerebellar ataxia; bipolar disorder; cerebellar ataxia; and muscular dystrophy. Orthologous to human SYNE1 (spectrin repeat containing nuclear envelope protein 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: CPG2; LOC102546492; Myne-1; nesprin-1; nesprin-1-like; spectrin repeat containing, nuclear envelope 1
Orthologs:
Allele / Splice: Syne1Tn(sb-T2/Bart3)2.68Mcwi  
Genetic Models: F344-Syne1Tn(sb-T2/Bart3)2.68Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0141,844,840 - 42,086,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0141,608,287 - 41,763,591 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl141,608,418 - 42,077,535 (-)Ensembl
Rnor_5.0142,947,742 - 43,158,478 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4135,803,552 - 36,269,628 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1135,805,545 - 35,961,017 (-)NCBI
Celera137,192,707 - 37,662,090 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Syne1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620546
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.