Gene: Ryr2 (ryanodine receptor 2) Rattus norvegicus
Symbol: Ryr2
Name: ryanodine receptor 2
Description: ENCODES a protein that exhibits calcium-induced calcium release activity; ryanodine-sensitive calcium-release channel activity; scaffold protein binding; INVOLVED IN calcium ion transmembrane transport; ion transmembrane transport; manganese ion transmembrane transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH congestive heart failure; Diabetes Mellitus, Experimental ; arrhythmogenic right ventricular cardiomyopathy (ortholog); FOUND IN A band; cytoplasm; endoplasmic reticulum; INTERACTS WITH (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17beta-estradiol
Type: protein-coding
Also known as: cardiac muscle ryanodine receptor; cardiac muscle ryanodine receptor-calcium release channel; cardiac-type ryaodine receptor; LOC689560; ryanodine receptor 2, cardiac; ryanodine receptor type II; RyR; RYR-2; similar to ryanodine receptor 2, cardiac; type 2 ryanodine receptor
Homo sapiens (human) : RYR2 (ryanodine receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Ryr2 (ryanodine receptor 2, cardiac)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ryr2 (ryanodine receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RYR2 (ryanodine receptor 2)
Canis lupus familiaris (dog) : RYR2 (ryanodine receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ryr2 (ryanodine receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01765,533,998 - 65,955,606 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01767,285,205 - 67,704,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41768,959,042 - 69,544,816 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11769,519,966 - 69,552,036 (+)NCBI
Celera1761,573,393 - 61,976,022 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ryr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620314
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-12-05
Status: ACTIVE