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Gene: Syne1 (spectrin repeat containing, nuclear envelope 1) Mus musculus
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Symbol: Syne1
Name: spectrin repeat containing, nuclear envelope 1
Description: Exhibits actin filament binding activity and protein homodimerization activity. Involved in centrosome localization; nuclear migration; and regulation of cilium assembly. Localizes to the nuclear envelope. Used to study Emery-Dreifuss muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 4; autosomal recessive cerebellar ataxia; bipolar disorder; cerebellar ataxia; and muscular dystrophy. Is expressed in several structures, including alimentary system; ear; genitourinary system; musculoskeletal system; and nervous system. Orthologous to human SYNE1 (spectrin repeat containing nuclear envelope protein 1); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8B; A330049M09Rik; BE692247; C130039F11Rik; CPG2; enaptin; enaptin165; KASH domain-containing protein 1; KASH1; KIAA1756; MGC62825; mKIAA1756; myne-1; Myne1; myocyte nuclear envelope protein 1; nesprin 1; nesprin-1; nuclear envelope spectrin repeat protein 1; synaptic nuclear envelope 1; synaptic nuclear envelope protein 1
Orthologs:
Related Pseudogenes: Gm18381  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38105,020,192 - 5,550,692 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37104,795,849 - 5,326,349 (+)NCBIGRCm37mm9NCBIm37
MGSCv36104,795,849 - 5,324,786 (+)NCBImm8
Celera104,962,310 - 5,494,074 (-)NCBICelera
Cytogenetic Map10 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences