Strain: SD-Nlgn3em1Sage

Symbol: SD-Nlgn3em1Sage
Strain: SD-Nlgn3em1
Substrain: Sage
Ontology ID: RS:0004311
Alleles: Nlgn3em1Sage
Also known as: SD-Nlgn3tm1Sage; TGRS6650; SD-Nlgn3em1Sage
Type: mutant
Source: Horizon Discovery
Origin: The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Nlgn3 into Sprague Dawley embryos. Homozygous knockout rats exhibit complete loss of target protein as demonstrated by Western blot.
Genetic Status: Heterozygous
Last Known Status: Live Animals; Cryopreserved Embryo (as of 2016-12-13)
Research Usage Autism, Asperger's syndrome, Synaptic plasticity
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X71,199,390 - 71,227,460RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X72,051,846 - 72,075,119RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4X89,376,193 - 89,398,665RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations
Phenotype Annotations
Experimental Data Annotations
References - curated
RGD Disease Portals


Additional Information

More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 11568700
Created: 2016-12-13
Species: Rattus norvegicus
Last Modified: 2016-12-13
Status: ACTIVE