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Gene: Dmd (dystrophin) Rattus norvegicus
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Symbol: Dmd
Name: dystrophin
Description: Exhibits several functions, including PDZ domain binding activity; integrin binding activity; and lamin binding activity. Involved in several processes, including nervous system development; response to denervation involved in regulation of muscle adaptation; and response to water deprivation. Localizes to several cellular components, including the mitochondrial membrane; neurofilament; and secretory vesicle. Used to study Duchenne muscular dystrophy; brain edema; and dilated cardiomyopathy. Biomarker of muscular atrophy; retinal degeneration; and status epilepticus. Human ortholog(s) of this gene implicated in cognitive disorder; dilated cardiomyopathy (multiple); intellectual disability; and muscular dystrophy (multiple). Orthologous to human DMD (dystrophin); INTERACTS WITH (+)-pilocarpine; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apodystrophin-3; apodystrophin-I; DNADMD1; dystrophin transcript variant Dp71e; dystrophin, muscular dystrophy; dystrophin-related; RATDMD; RNDNADMD1
Orthologs:
Homo sapiens (human) : DMD (dystrophin)  HGNC  Alliance
Mus musculus (house mouse) : Dmd (dystrophin, muscular dystrophy)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dmd (dystrophin)
Pan paniscus (bonobo/pygmy chimpanzee) : DMD (dystrophin)
Canis lupus familiaris (dog) : DMD (dystrophin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dmd (dystrophin)
Sus scrofa (pig) : DMD (dystrophin)
more info ...
Allele / Splice: Dmdem1Kykn   Dmdem1Ang  
Genetic Models: SD-Dmdem1Ang W-Dmdem1Kykn
Is Marker For: Strains:   W-Dmdem2Kykn   W-Dmdem3Kykn  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X51,149,358 - 53,519,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX51,286,737 - 53,519,259 (+)Ensembl
Rnor_5.0X51,475,950 - 53,700,033 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X71,501,362 - 71,671,414 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X71,574,653 - 71,744,706 (+)NCBI
CeleraX49,967,398 - 50,127,432 (+)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

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