Mylip (myosin regulatory light chain interacting protein) - Rat Genome Database

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Gene: Mylip (myosin regulatory light chain interacting protein) Rattus norvegicus
Analyze
Symbol: Mylip
Name: myosin regulatory light chain interacting protein
RGD ID: 1305761
Description: Predicted to enable cytoskeletal protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including cholesterol homeostasis; negative regulation of low-density lipoprotein particle clearance; and regulation of protein catabolic process. Predicted to be located in cytoplasm; cytoskeleton; and plasma membrane. Orthologous to human MYLIP (myosin regulatory light chain interacting protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase MYLIP; idol; inducible degrader of the LDL-receptor; LOC306825; MIR; RING-type E3 ubiquitin transferase MYLIP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Mylipem2Mcwi   Mylipem3Mcwi   Mylipem1Mcwi  
Genetic Models: SS-Mylipem2Mcwi SS-Mylipem3Mcwi SS-Mylipem1Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21719,286,649 - 19,308,295 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1719,286,650 - 19,308,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1719,171,096 - 19,192,723 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01720,774,907 - 20,796,527 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01719,098,217 - 19,119,846 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01719,682,040 - 19,703,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1719,682,040 - 19,703,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01721,703,590 - 21,725,205 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41725,308,147 - 25,329,887 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11725,312,367 - 25,523,199 (-)NCBI
Celera1718,989,082 - 19,010,552 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allethrin  (EXP)
Archazolid B  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-hexachlorocyclohexane  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
cytarabine  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
GW 3965  (ISO)
GW 4064  (ISO)
Heptachlor epoxide  (ISO)
hydroquinone  (ISO)
isoprenaline  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
maneb  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mifepristone  (EXP)
mitomycin C  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenobarbital  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
pyrethrins  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. (-)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B. Wang W, etal., Front Pharmacol. 2018 Mar 9;9:195. doi: 10.3389/fphar.2018.00195. eCollection 2018.
Additional References at PubMed
PMID:10593918   PMID:14550572   PMID:19028597   PMID:19520913   PMID:21685362   PMID:23990472   PMID:24166456  


Genomics

Comparative Map Data
Mylip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21719,286,649 - 19,308,295 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1719,286,650 - 19,308,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1719,171,096 - 19,192,723 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01720,774,907 - 20,796,527 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01719,098,217 - 19,119,846 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01719,682,040 - 19,703,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1719,682,040 - 19,703,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01721,703,590 - 21,725,205 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41725,308,147 - 25,329,887 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11725,312,367 - 25,523,199 (-)NCBI
Celera1718,989,082 - 19,010,552 (-)NCBICelera
Cytogenetic Map17p14NCBI
MYLIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38616,129,086 - 16,163,887 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl616,129,086 - 16,148,248 (+)EnsemblGRCh38hg38GRCh38
GRCh37616,129,317 - 16,148,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36616,237,296 - 16,256,458 (+)NCBINCBI36Build 36hg18NCBI36
Build 34616,237,295 - 16,256,455NCBI
Celera617,367,147 - 17,386,309 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef616,076,513 - 16,095,715 (+)NCBIHuRef
CHM1_1616,132,017 - 16,151,181 (+)NCBICHM1_1
T2T-CHM13v2.0616,001,663 - 16,037,439 (+)NCBIT2T-CHM13v2.0
Mylip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391345,543,197 - 45,565,498 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1345,543,218 - 45,565,498 (+)EnsemblGRCm39 Ensembl
GRCm381345,389,742 - 45,411,940 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1345,389,742 - 45,412,022 (+)EnsemblGRCm38mm10GRCm38
MGSCv371345,485,111 - 45,507,309 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361345,400,714 - 45,422,912 (+)NCBIMGSCv36mm8
Celera1346,464,431 - 46,486,733 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1321.88NCBI
Mylip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554839,723,023 - 9,745,062 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554839,725,343 - 9,745,041 (-)NCBIChiLan1.0ChiLan1.0
MYLIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1626,780,496 - 26,801,629 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0615,985,844 - 16,005,043 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1616,350,852 - 16,370,253 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl616,350,852 - 16,370,253 (+)Ensemblpanpan1.1panPan2
MYLIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13515,257,633 - 15,276,771 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3515,256,885 - 15,275,424 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3515,205,869 - 15,225,698 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03515,352,342 - 15,372,171 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3515,352,164 - 15,370,824 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13515,177,056 - 15,196,883 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03515,228,888 - 15,248,707 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03516,555,131 - 16,574,958 (+)NCBIUU_Cfam_GSD_1.0
Mylip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049469,389,585 - 9,405,771 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365522,325,378 - 2,339,867 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365522,325,161 - 2,341,356 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYLIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl712,117,240 - 12,137,925 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1712,117,240 - 12,137,934 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2712,713,066 - 12,733,740 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYLIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11756,021,151 - 56,040,175 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1756,022,369 - 56,040,169 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604416,181,768 - 16,200,965 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mylip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475610,324,021 - 10,343,787 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475610,324,275 - 10,343,047 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mylip
73 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:223
Count of miRNA genes:153
Interacting mature miRNAs:181
Transcripts:ENSRNOT00000024021
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)17429913021293263Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171533061323017269Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat

Markers in Region
AA818380  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,286,948 - 19,287,129 (+)MAPPERmRatBN7.2
Rnor_6.01719,682,339 - 19,682,519NCBIRnor6.0
Rnor_5.01721,703,889 - 21,704,069UniSTSRnor5.0
RGSC_v3.41725,308,439 - 25,308,619UniSTSRGSC3.4
Celera1718,989,381 - 18,989,561UniSTS
RH 3.4 Map17246.9UniSTS
Cytogenetic Map17p12UniSTS
AI411450  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,306,413 - 19,306,595 (+)MAPPERmRatBN7.2
Rnor_6.01719,701,801 - 19,701,982NCBIRnor6.0
Rnor_5.01721,723,325 - 21,723,506UniSTSRnor5.0
RGSC_v3.41725,328,007 - 25,328,188UniSTSRGSC3.4
Celera1719,008,667 - 19,008,848UniSTS
RH 3.4 Map17248.8UniSTS
Cytogenetic Map17p12UniSTS


Genetic Models
This gene Mylip is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 12 29 14 19 14 2 2 25 35 34 11 2
Low 31 28 27 27 6 9 49 7 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000024021   ⟹   ENSRNOP00000024021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1719,286,650 - 19,308,295 (-)Ensembl
Rnor_6.0 Ensembl1719,682,040 - 19,703,681 (-)Ensembl
RefSeq Acc Id: NM_001107344   ⟹   NP_001100814
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,286,650 - 19,308,295 (-)NCBI
Rnor_6.01719,682,040 - 19,703,681 (-)NCBI
Rnor_5.01721,703,590 - 21,725,205 (-)NCBI
RGSC_v3.41725,308,147 - 25,329,887 (-)RGD
Celera1718,989,082 - 19,010,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095672   ⟹   XP_038951600
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,286,649 - 19,294,813 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100814 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951600 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D3ZDI6 (Get FASTA)   NCBI Sequence Viewer  
  EDL98172 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024021
  ENSRNOP00000024021.4
RefSeq Acc Id: NP_001100814   ⟸   NM_001107344
- UniProtKB: D3ZDI6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024021   ⟸   ENSRNOT00000024021
RefSeq Acc Id: XP_038951600   ⟸   XM_039095672
- Peptide Label: isoform X1
Protein Domains
FERM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDI6-F1-model_v2 AlphaFold D3ZDI6 1-445 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700372
Promoter ID:EPDNEW_R10895
Type:single initiation site
Name:Mylip_1
Description:myosin regulatory light chain interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01719,703,680 - 19,703,740EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305761 AgrOrtholog
BioCyc Gene G2FUF-9860 BioCyc
Ensembl Genes ENSRNOG00000017579 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024021 ENTREZGENE
  ENSRNOT00000024021.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro Band_41_domain UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  MYLIP_FERM_C UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
NCBI Gene 306825 ENTREZGENE
PANTHER 4.1 G PROTEIN UniProtKB/Swiss-Prot
  E3 UBIQUITIN-PROTEIN LIGASE MYLIP UniProtKB/Swiss-Prot
Pfam FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  zf-C3HC4_3 UniProtKB/Swiss-Prot
PhenoGen Mylip PhenoGen
PRINTS BAND41 UniProtKB/Swiss-Prot
  ERMFAMILY UniProtKB/Swiss-Prot
PROSITE FERM_3 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017579 RatGTEx
SMART B41 UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  RING/U-box UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt D3ZDI6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mylip  myosin regulatory light chain interacting protein   Mylip_predicted  myosin regulatory light chain interacting protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mylip_predicted  myosin regulatory light chain interacting protein (predicted)      Symbol and Name status set to approved 70820 APPROVED