(+)-alpha-tocopherol multiple interactions ISO RGD:1353510 6480464 alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased activity of TERT protein] CTD PMID:20112180 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TERT mRNA] CTD PMID:31150632 (-)-demecolcine decreases expression ISO RGD:1353510 6480464 Demecolcine results in decreased expression of TERT mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:1353510 6480464 epigallocatechin gallate results in decreased expression of TERT mRNA, epigallocatechin gallate results in decreased expression of TERT protein CTD PMID:18581255 , PMID:20706672 1-(5-isoquinolinesulfonyl)-2-methylpiperazine decreases activity ISO RGD:1353510 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of TERT protein CTD PMID:9434777 17beta-estradiol multiple interactions ISO RGD:1353510 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein] more ... CTD PMID:16051634 more ... 17beta-estradiol increases activity ISO RGD:1353510 6480464 Estradiol results in increased activity of TERT protein CTD PMID:16327978 more ... 17beta-estradiol multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein] more ... CTD PMID:15590986 17beta-estradiol increases expression ISO RGD:1353510 6480464 Estradiol results in increased expression of TERT more ... CTD PMID:15585566 more ... 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases activity ISO RGD:1353510 6480464 Metribolone results in increased activity of TERT protein CTD PMID:19561322 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:1353510 6480464 Metribolone results in increased expression of TERT mRNA CTD PMID:19561322 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:1353510 6480464 letrozole inhibits the reaction [Metribolone results in increased activity of TERT protein] more ... CTD PMID:19561322 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1353510 6480464 2 more ... CTD PMID:26330309 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression ISO RGD:1353510 6480464 2 more ... CTD PMID:26330309 2,2',4,4',5,5'-hexachlorobiphenyl increases activity ISO RGD:1353510 6480464 2 more ... CTD PMID:26330309 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1353510 6480464 [Tetrachlorodibenzodioxin co-treated with Estradiol] results in increased activity of TERT protein more ... CTD PMID:16327978 , PMID:17141429 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:70505 6480464 Tetrachlorodibenzodioxin results in increased expression of TERT mRNA CTD PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:70505 6480464 Tetrachlorodibenzodioxin affects the expression of TERT mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:70505 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of TERT mRNA CTD PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine increases activity EXP 6480464 Tetrachlorodibenzodioxin results in increased activity of TERT protein CTD PMID:16327978 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 MYC protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of TERT protein] CTD PMID:16327978 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1353510 6480464 Tetrachlorodibenzodioxin results in increased expression of TERT mRNA CTD PMID:16327978 , PMID:17141429 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO RGD:1353510 6480464 Tetrachlorodibenzodioxin results in increased activity of TERT protein CTD PMID:16327978 3,3',4,4',5-pentachlorobiphenyl decreases activity ISO RGD:1353510 6480464 3 more ... CTD PMID:26330309 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:1353510 6480464 3 more ... CTD PMID:26330309 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:1353510 6480464 3 more ... CTD PMID:26330309 3-aminobenzamide multiple interactions ISO RGD:1353510 6480464 3-aminobenzamide inhibits the reaction [TERT protein mutant form results in decreased susceptibility to temozolomide] CTD PMID:12488552 4,4'-diaminodiphenylmethane affects expression ISO RGD:70505 6480464 4, 4'-diaminodiphenylmethane affects the expression of TERT mRNA CTD PMID:18648102 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid multiple interactions ISO RGD:1353510 6480464 [Am 580 co-treated with Retinoids] results in decreased expression of TERT mRNA CTD PMID:16482212 4-hydroperoxycyclophosphamide decreases expression ISO RGD:70505 6480464 perfosfamide results in decreased expression of TERT mRNA CTD PMID:24571982 5-(2-methylpiperazine-1-sulfonyl)isoquinoline decreases activity ISO RGD:1353510 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of TERT protein CTD PMID:9434777 5-aza-2'-deoxycytidine affects expression ISO RGD:1353510 6480464 Decitabine affects the expression of TERT mRNA CTD PMID:18045574 5-aza-2'-deoxycytidine decreases expression ISO RGD:1353510 6480464 Decitabine results in decreased expression of TERT protein CTD PMID:18021753 5-aza-2'-deoxycytidine affects methylation ISO RGD:1353510 6480464 Decitabine affects the methylation of TERT promoter CTD PMID:17267411 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1353510 6480464 [Decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Cisplatin more ... CTD PMID:17267411 , PMID:18021753 5-aza-2'-deoxycytidine decreases activity ISO RGD:1353510 6480464 Decitabine results in decreased activity of TERT protein CTD PMID:18021753 5-azacytidine decreases expression ISO RGD:1353510 6480464 Azacitidine analog results in decreased expression of TERT mRNA, Azacitidine results in decreased expression of TERT mRNA CTD PMID:18045574 , PMID:19451745 5-azacytidine multiple interactions ISO RGD:1353510 6480464 E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein] more ... CTD PMID:19451745 5-azacytidine decreases methylation ISO RGD:1353510 6480464 Azacitidine results in decreased methylation of TERT promoter CTD PMID:19451745 5-azacytidine decreases activity ISO RGD:1353510 6480464 Azacitidine results in decreased activity of TERT protein CTD PMID:19451745 5-fluorouracil multiple interactions ISO RGD:1353510 6480464 [Fluorouracil co-treated with gemcitabine] results in decreased activity of TERT protein, TP53 protein affects the reaction [Fluorouracil results in decreased expression of TERT mRNA] CTD PMID:15016801 , PMID:16929163 5-fluorouracil decreases expression ISO RGD:70505 6480464 Fluorouracil results in decreased expression of TERT protein CTD PMID:21296659 5-fluorouracil affects response to substance ISO RGD:1353510 6480464 TERT protein affects the susceptibility to Fluorouracil CTD PMID:15608686 5-fluorouracil decreases response to substance ISO RGD:1353510 6480464 TERT mRNA results in decreased susceptibility to Fluorouracil CTD PMID:18396642 5-fluorouracil decreases expression ISO RGD:1353510 6480464 Fluorouracil results in decreased expression of TERT mRNA more ... CTD PMID:15003732 more ... 5-fluorouracil decreases activity ISO RGD:1353510 6480464 Fluorouracil results in decreased activity of TERT protein CTD PMID:16929163 9-cis-retinoic acid decreases expression ISO RGD:70505 6480464 Alitretinoin results in decreased expression of TERT mRNA CTD PMID:16180984 abacavir decreases activity ISO RGD:1353510 6480464 abacavir results in decreased activity of TERT protein CTD PMID:19358275 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of TERT mRNA CTD PMID:31881176 acetic acid affects expression ISO RGD:70505 6480464 Acetic Acid affects the expression of TERT protein CTD PMID:21296659 acetylsalicylic acid increases expression ISO RGD:1353510 6480464 Aspirin results in increased expression of TERT mRNA CTD PMID:20457246 aflatoxin B1 increases expression ISO RGD:70505 6480464 Aflatoxin B1 results in increased expression of TERT mRNA CTD PMID:19770486 aflatoxin B1 increases methylation ISO RGD:1353510 6480464 Aflatoxin B1 results in increased methylation of TERT intron CTD PMID:30157460 aflatoxin B2 affects methylation ISO RGD:1353510 6480464 aflatoxin B2 affects the methylation of TERT intron CTD PMID:30157460 all-trans-retinoic acid multiple interactions ISO RGD:1353510 6480464 2 more ... CTD PMID:16107885 more ... all-trans-retinoic acid decreases activity ISO RGD:1353510 6480464 Tretinoin results in decreased activity of TERT protein CTD PMID:15770638 more ... all-trans-retinoic acid decreases expression ISO RGD:1353510 6480464 Tretinoin results in decreased expression of TERT mRNA, Tretinoin results in decreased expression of TERT protein CTD PMID:15770638 more ... all-trans-retinoic acid decreases expression ISO RGD:70505 6480464 Tretinoin results in decreased expression of TERT mRNA CTD PMID:16180984 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TERT mRNA CTD PMID:16483693 anilines decreases activity ISO RGD:1353510 6480464 Aniline Compounds results in decreased activity of TERT protein CTD PMID:25123791 anilines decreases expression ISO RGD:1353510 6480464 Aniline Compounds results in decreased expression of TERT mRNA CTD PMID:25123791 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1353510 6480464 [pyrazolanthrone co-treated with SB 203580 co-treated with U 0126] inhibits the reaction [Isothiocyanates results in increased expression of TERT mRNA] CTD PMID:23382840 antirheumatic drug decreases expression ISO RGD:1353510 6480464 Antirheumatic Agents results in decreased expression of TERT mRNA CTD PMID:24449571 arsane increases expression ISO RGD:1353510 6480464 Arsenic results in increased expression of TERT mRNA CTD PMID:19337508 , PMID:22917110 arsane affects methylation ISO RGD:1353510 6480464 Arsenic affects the methylation of TERT gene CTD PMID:25304211 arsenic atom increases expression ISO RGD:1353510 6480464 Arsenic results in increased expression of TERT mRNA CTD PMID:19337508 , PMID:22917110 arsenic atom affects methylation ISO RGD:1353510 6480464 Arsenic affects the methylation of TERT gene CTD PMID:25304211 arsenous acid decreases activity ISO RGD:1353510 6480464 Arsenic Trioxide results in decreased activity of TERT mRNA, Arsenic Trioxide results in decreased activity of TERT protein CTD PMID:12962562 more ... arsenous acid multiple interactions ISO RGD:1353510 6480464 [Arsenic Trioxide co-treated with VS-5584] results in decreased expression of TERT mRNA more ... CTD PMID:11714746 more ... arsenous acid decreases activity ISO RGD:70505 6480464 Arsenic Trioxide results in decreased activity of TERT protein CTD PMID:18336854 arsenous acid decreases expression ISO RGD:1353510 6480464 Arsenic Trioxide results in decreased expression of TERT gene more ... CTD PMID:11714746 more ... arsenous acid multiple interactions ISO RGD:70505 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of TERT protein] more ... CTD PMID:18336854 benzamide decreases activity ISO RGD:1353510 6480464 benzamide results in decreased activity of TERT protein CTD PMID:16098204 benzamide decreases ADP-ribosylation ISO RGD:1353510 6480464 benzamide results in decreased ADP-ribosylation of TERT protein CTD PMID:16098204 benzene multiple interactions ISO RGD:70505 6480464 [Benzene co-treated with Selenium] results in increased activity of TERT protein CTD PMID:19080380 benzene increases activity ISO RGD:70505 6480464 Benzene results in increased activity of TERT protein CTD PMID:19080380 benzo[e]pyrene increases methylation ISO RGD:1353510 6480464 benzo(e)pyrene results in increased methylation of TERT intron CTD PMID:30157460 berberine decreases activity ISO RGD:1353510 6480464 Berberine results in decreased activity of TERT protein CTD PMID:25265580 bicalutamide decreases expression ISO RGD:1353510 6480464 bicalutamide results in decreased expression of TERT mRNA CTD PMID:15638997 bicalutamide decreases activity ISO RGD:1353510 6480464 bicalutamide results in decreased activity of TERT protein CTD PMID:15638997 bisphenol A increases expression ISO RGD:1353510 6480464 bisphenol A results in increased expression of TERT mRNA CTD PMID:15368248 bisphenol A multiple interactions ISO RGD:1353510 6480464 1 more ... CTD PMID:29192164 bisphenol A decreases activity ISO RGD:1353510 6480464 bisphenol A results in decreased activity of TERT protein CTD PMID:29192164 bisphenol A affects methylation ISO RGD:70505 6480464 bisphenol A affects the methylation of TERT promoter CTD PMID:27334623 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TERT mRNA CTD PMID:25181051 , PMID:30816183 bleomycin A2 decreases response to substance ISO RGD:70505 6480464 TERT gene mutant form results in decreased susceptibility to Bleomycin CTD PMID:18008008 Boldine affects splicing ISO RGD:1353510 6480464 boldine affects the splicing of TERT mRNA CTD PMID:25746354 Boldine decreases activity ISO RGD:1353510 6480464 boldine results in decreased activity of TERT protein CTD PMID:25746354 bromochloroacetic acid increases expression ISO RGD:70505 6480464 bromochloroacetic acid results in increased expression of TERT protein CTD PMID:21296659 bucladesine multiple interactions ISO RGD:1353510 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TERT mRNA CTD PMID:20823114 cadmium dichloride multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA] CTD PMID:16600092 cadmium dichloride increases activity EXP 6480464 Cadmium Chloride results in increased activity of TERT protein CTD PMID:21181359 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of TERT mRNA CTD PMID:16600092 , PMID:21181359 calcitriol decreases expression ISO RGD:1353510 6480464 Calcitriol results in decreased expression of TERT mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1353510 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of TERT mRNA CTD PMID:21592394 camptothecin increases expression ISO RGD:1353510 6480464 Camptothecin results in increased expression of TERT mRNA CTD PMID:30851366 camptothecin multiple interactions ISO RGD:1353510 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Camptothecin results in increased phosphorylation of TERT protein] more ... CTD PMID:30851366 carbon nanotube decreases expression ISO RGD:70505 6480464 Nanotubes, Carbon results in decreased expression of TERT mRNA CTD PMID:25620056 carmustine decreases response to substance ISO RGD:1353510 6480464 TERT protein mutant form results in decreased susceptibility to Carmustine CTD PMID:12488552 chelidonine decreases activity ISO RGD:1353510 6480464 chelidonine results in decreased activity of TERT protein CTD PMID:25265580 chelidonine decreases expression ISO RGD:1353510 6480464 chelidonine results in decreased expression of TERT mRNA CTD PMID:25265580 choline affects expression ISO RGD:1353510 6480464 Choline affects the expression of TERT mRNA CTD PMID:17616785 cisplatin multiple interactions ISO RGD:1353510 6480464 [Cisplatin co-treated with Quercetin] results in decreased activity of TERT protein more ... CTD PMID:16082193 more ... cisplatin decreases expression ISO RGD:70505 6480464 Cisplatin results in decreased expression of TERT mRNA CTD PMID:24571982 cisplatin decreases expression ISO RGD:1353510 6480464 Cisplatin results in decreased expression of TERT mRNA CTD PMID:17923759 , PMID:27594783 cisplatin increases response to substance ISO RGD:1353510 6480464 TERT protein mutant form results in increased susceptibility to Cisplatin CTD PMID:12488552 citric acid multiple interactions ISO RGD:1353510 6480464 [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT protein CTD PMID:16624386 copper(II) sulfate decreases expression ISO RGD:1353510 6480464 Copper Sulfate results in decreased expression of TERT mRNA CTD PMID:19549813 curcumin decreases activity ISO RGD:1353510 6480464 Curcumin results in decreased activity of TERT protein CTD PMID:17096185 diarsenic trioxide multiple interactions ISO RGD:70505 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of TERT protein] more ... CTD PMID:18336854 diarsenic trioxide decreases activity ISO RGD:1353510 6480464 Arsenic Trioxide results in decreased activity of TERT mRNA, Arsenic Trioxide results in decreased activity of TERT protein CTD PMID:12962562 more ... diarsenic trioxide multiple interactions ISO RGD:1353510 6480464 [Arsenic Trioxide co-treated with VS-5584] results in decreased expression of TERT mRNA more ... CTD PMID:11714746 more ... diarsenic trioxide decreases expression ISO RGD:1353510 6480464 Arsenic Trioxide results in decreased expression of TERT gene more ... CTD PMID:11714746 more ... diarsenic trioxide decreases activity ISO RGD:70505 6480464 Arsenic Trioxide results in decreased activity of TERT protein CTD PMID:18336854 dibenziodolium multiple interactions ISO RGD:70505 6480464 diphenyleneiodonium inhibits the reaction [Arsenic Trioxide results in decreased activity of TERT protein], diphenyleneiodonium inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein] CTD PMID:18336854 dibenzoylmethane multiple interactions ISO RGD:1353510 6480464 dibenzoylmethane inhibits the reaction [ESR1 protein binds to TERT enhancer], dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of TERT mRNA] CTD PMID:16051634 dicrotophos increases expression ISO RGD:1353510 6480464 dicrotophos results in increased expression of TERT mRNA CTD PMID:28302478 dimethyl sulfoxide multiple interactions ISO RGD:1353510 6480464 2 more ... CTD PMID:26330309 dimethyl sulfoxide decreases expression ISO RGD:70505 6480464 Dimethyl Sulfoxide results in decreased expression of TERT mRNA CTD PMID:16180984 disodium selenite increases activity ISO RGD:1353510 6480464 Sodium Selenite results in increased activity of TERT protein CTD PMID:14673504 disodium selenite increases expression ISO RGD:1353510 6480464 Sodium Selenite results in increased expression of TERT mRNA CTD PMID:14673504 doxorubicin decreases expression ISO RGD:1353510 6480464 Doxorubicin results in decreased expression of TERT mRNA, Doxorubicin results in decreased expression of TERT mRNA alternative form CTD PMID:15003732 , PMID:16077987 doxorubicin decreases response to substance ISO RGD:1353510 6480464 TERT mRNA results in decreased susceptibility to Doxorubicin CTD PMID:18396642 doxorubicin increases expression ISO RGD:1353510 6480464 Doxorubicin results in increased expression of TERT mRNA CTD PMID:18560228 elemental selenium decreases activity ISO RGD:1353510 6480464 Selenium results in decreased activity of TERT protein CTD PMID:17948765 elemental selenium multiple interactions ISO RGD:70505 6480464 [Benzene co-treated with Selenium] results in increased activity of TERT protein CTD PMID:19080380 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA] CTD PMID:16600092 elemental selenium decreases expression ISO RGD:1353510 6480464 Selenium results in decreased expression of TERT mRNA CTD PMID:17948765 ellagic acid multiple interactions ISO RGD:1353510 6480464 Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form] CTD PMID:19501078 ellagic acid multiple interactions EXP 6480464 Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein] CTD PMID:27965107 ellagic acid increases expression ISO RGD:1353510 6480464 Ellagic Acid results in increased expression of TERT mRNA alternative form CTD PMID:19501078 endosulfan increases expression ISO RGD:1353510 6480464 Endosulfan results in increased expression of TERT mRNA CTD PMID:15832825 endosulfan increases expression ISO RGD:70505 6480464 Endosulfan results in increased expression of TERT mRNA CTD PMID:15832825 ethyl methanesulfonate decreases expression ISO RGD:1353510 6480464 Ethyl Methanesulfonate results in decreased expression of TERT mRNA CTD PMID:23649840 fonofos increases methylation ISO RGD:1353510 6480464 Fonofos results in increased methylation of TERT promoter CTD PMID:22847954 formaldehyde increases expression ISO RGD:1353510 6480464 Formaldehyde results in increased expression of TERT mRNA CTD PMID:18045764 formaldehyde decreases expression ISO RGD:1353510 6480464 Formaldehyde results in decreased expression of TERT mRNA CTD PMID:23649840 fulvestrant multiple interactions ISO RGD:1353510 6480464 fulvestrant inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form] CTD PMID:19501078 fulvestrant decreases expression ISO RGD:1353510 6480464 fulvestrant results in decreased expression of TERT mRNA alternative form CTD PMID:19501078 fumagillin multiple interactions EXP 6480464 fumagillin inhibits the reaction [Diethylnitrosamine results in increased activity of TERT protein], fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of TERT mRNA] CTD PMID:15682466 furan increases methylation EXP 6480464 furan results in increased methylation of TERT gene CTD PMID:22079235 gefitinib decreases expression ISO RGD:1353510 6480464 gefitinib results in decreased expression of TERT mRNA CTD PMID:17094457 gemcitabine multiple interactions ISO RGD:1353510 6480464 [Fluorouracil co-treated with gemcitabine] results in decreased activity of TERT protein CTD PMID:16929163 gemcitabine decreases activity ISO RGD:1353510 6480464 gemcitabine results in decreased activity of TERT protein CTD PMID:16929163 genistein decreases expression ISO RGD:1353510 6480464 Genistein results in decreased expression of TERT mRNA CTD PMID:20706672 glutathione increases expression ISO RGD:1353510 6480464 Glutathione results in increased expression of TERT protein CTD PMID:30851366 glutathione multiple interactions ISO RGD:1353510 6480464 Glutathione inhibits the reaction [Camptothecin results in increased expression of TERT protein] CTD PMID:30851366 Honokiol decreases expression ISO RGD:1353510 6480464 honokiol results in decreased expression of TERT mRNA CTD PMID:27259399 hydrogen peroxide decreases activity ISO RGD:1353510 6480464 Hydrogen Peroxide results in decreased activity of TERT protein CTD PMID:20112180 hydrogen peroxide decreases expression ISO RGD:1353510 6480464 Hydrogen Peroxide results in decreased expression of TERT mRNA CTD PMID:15761015 hydrogen peroxide multiple interactions ISO RGD:1353510 6480464 alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased activity of TERT protein] CTD PMID:20112180 iron atom increases activity EXP 6480464 Iron results in increased activity of TERT protein CTD PMID:17189828 iron(0) increases activity EXP 6480464 Iron results in increased activity of TERT protein CTD PMID:17189828 isothiocyanate multiple interactions ISO RGD:1353510 6480464 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole co-treated with 1 more ... CTD PMID:23382840 isothiocyanate increases expression ISO RGD:1353510 6480464 Isothiocyanates results in increased expression of TERT mRNA CTD PMID:23382840 isothiocyanate decreases expression ISO RGD:1353510 6480464 Isothiocyanates results in decreased expression of TERT mRNA CTD PMID:23382840 isothiocyanate increases activity ISO RGD:1353510 6480464 Isothiocyanates results in increased activity of TERT protein CTD PMID:23382840 isothiocyanate decreases activity ISO RGD:1353510 6480464 Isothiocyanates results in decreased activity of TERT protein CTD PMID:23382840 isotretinoin decreases expression ISO RGD:70505 6480464 Isotretinoin results in decreased expression of TERT mRNA CTD PMID:16180984 letrozole multiple interactions ISO RGD:1353510 6480464 letrozole inhibits the reaction [Metribolone results in increased activity of TERT protein] CTD PMID:19561322 LY294002 multiple interactions ISO RGD:1353510 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Camptothecin results in increased phosphorylation of TERT protein] more ... CTD PMID:16798746 , PMID:30851366 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein] CTD PMID:15590986 mangiferin decreases activity ISO RGD:1353510 6480464 mangiferin results in decreased activity of TERT protein CTD PMID:17634039 Manumycin A multiple interactions ISO RGD:1353510 6480464 Acetylcysteine inhibits the reaction [manumycin results in decreased expression of TERT protein] CTD PMID:19409983 Manumycin A decreases expression ISO RGD:1353510 6480464 manumycin results in decreased expression of TERT protein CTD PMID:19409983 medroxyprogesterone acetate multiple interactions ISO RGD:1353510 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TERT mRNA CTD PMID:20823114 methapyrilene increases methylation ISO RGD:1353510 6480464 Methapyrilene results in increased methylation of TERT intron CTD PMID:30157460 mitomycin C decreases expression ISO RGD:1353510 6480464 Mitomycin results in decreased expression of TERT protein CTD PMID:24838295 N-acetyl-L-cysteine increases expression ISO RGD:1353510 6480464 Acetylcysteine results in increased expression of TERT protein CTD PMID:30851366 N-acetyl-L-cysteine multiple interactions ISO RGD:70505 6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein], Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein] CTD PMID:18336854 N-acetyl-L-cysteine multiple interactions ISO RGD:1353510 6480464 Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of TERT protein], Acetylcysteine inhibits the reaction [manumycin results in decreased expression of TERT protein] CTD PMID:19409983 , PMID:30851366 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:70505 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] CTD PMID:21520056 N-nitrosodiethylamine multiple interactions ISO RGD:70505 6480464 ATM protein promotes the reaction [Diethylnitrosamine results in increased expression of TERT protein] CTD PMID:19919837 N-nitrosodiethylamine multiple interactions EXP 6480464 fumagillin inhibits the reaction [Diethylnitrosamine results in increased activity of TERT protein], fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of TERT mRNA] CTD PMID:15682466 N-nitrosodiethylamine increases activity EXP 6480464 Diethylnitrosamine results in increased activity of TERT protein CTD PMID:15682466 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of TERT mRNA CTD PMID:15682466 N-nitrosodiethylamine increases expression ISO RGD:70505 6480464 Diethylnitrosamine results in increased expression of TERT protein CTD PMID:19919837 Nandrolone decanoate increases activity ISO RGD:1353510 6480464 nandrolone decanoate results in increased activity of TERT protein CTD PMID:19561322 Osajin decreases expression ISO RGD:1353510 6480464 osajin results in decreased expression of TERT mRNA CTD PMID:20706672 paclitaxel multiple interactions ISO RGD:1353510 6480464 [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Paclitaxel, [Tretinoin co-treated with Paclitaxel] results in decreased expression of TERT protein CTD PMID:17701358 more ... paclitaxel decreases expression ISO RGD:1353510 6480464 Paclitaxel results in decreased expression of TERT protein CTD PMID:17701358 , PMID:18098270 parathion increases methylation ISO RGD:1353510 6480464 Parathion results in increased methylation of TERT promoter CTD PMID:22847954 phorbol 13-acetate 12-myristate decreases expression ISO RGD:1353510 6480464 Tetradecanoylphorbol Acetate results in decreased expression of TERT mRNA CTD PMID:26330309 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1353510 6480464 2 more ... CTD PMID:26330309 phorbol 13-acetate 12-myristate decreases activity ISO RGD:1353510 6480464 Tetradecanoylphorbol Acetate results in decreased activity of TERT protein CTD PMID:26330309 phosalone decreases activity EXP 6480464 phosalone results in decreased activity of TERT protein CTD PMID:27965107 phosalone multiple interactions EXP 6480464 Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein] CTD PMID:27965107 platycodin D multiple interactions ISO RGD:1353510 6480464 [platycodin D results in decreased activity of AKT1 protein] which results in decreased phosphorylation of and results in decreased localization of TERT protein CTD PMID:18093727 platycodin D decreases expression ISO RGD:1353510 6480464 platycodin D results in decreased expression of TERT mRNA CTD PMID:18093727 Pomiferin decreases expression ISO RGD:1353510 6480464 pomiferin results in decreased expression of TERT mRNA CTD PMID:20706672 pterostilbene decreases expression ISO RGD:1353510 6480464 pterostilbene results in decreased expression of TERT mRNA, pterostilbene results in decreased expression of TERT protein CTD PMID:26459286 pterostilbene multiple interactions ISO RGD:1353510 6480464 Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT mRNA], Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT protein] CTD PMID:26459286 puerarin decreases expression ISO RGD:1353510 6480464 puerarin results in decreased expression of TERT mRNA CTD PMID:20706672 quercetin multiple interactions ISO RGD:1353510 6480464 [Cisplatin co-treated with Quercetin] results in decreased activity of TERT protein CTD PMID:16082193 quercetin increases activity ISO RGD:1353510 6480464 Quercetin results in increased activity of TERT protein CTD PMID:21902895 quercetin increases expression ISO RGD:1353510 6480464 Quercetin results in increased expression of TERT mRNA CTD PMID:21632981 raloxifene increases phosphorylation ISO RGD:1353510 6480464 Raloxifene Hydrochloride results in increased phosphorylation of TERT protein CTD PMID:16798746 raloxifene multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein] more ... CTD PMID:15590986 raloxifene multiple interactions ISO RGD:1353510 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein] more ... CTD PMID:16798746 raloxifene increases expression ISO RGD:1353510 6480464 Raloxifene Hydrochloride results in increased expression of TERT mRNA CTD PMID:16798746 reactive oxygen species multiple interactions ISO RGD:1353510 6480464 [arsenic trioxide results in increased abundance of Reactive Oxygen Species] which results in decreased expression of TERT mRNA, [monomethylarsonous acid results in increased abundance of Reactive Oxygen Species] which results in decreased expression of TERT mRNA CTD PMID:18336854 reactive oxygen species affects expression ISO RGD:1353510 6480464 Reactive Oxygen Species affects the expression of TERT mRNA CTD PMID:15761015 resveratrol decreases expression ISO RGD:1353510 6480464 resveratrol results in decreased expression of TERT mRNA CTD PMID:20706672 resveratrol multiple interactions ISO RGD:1353510 6480464 resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT mRNA], resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT protein] CTD PMID:26459286 Rosavin decreases expression ISO RGD:1353510 6480464 rosavin results in decreased expression of TERT mRNA CTD PMID:20706672 SB 203580 multiple interactions ISO RGD:1353510 6480464 [pyrazolanthrone co-treated with SB 203580 co-treated with U 0126] inhibits the reaction [Isothiocyanates results in increased expression of TERT mRNA] CTD PMID:23382840 selenium atom decreases activity ISO RGD:1353510 6480464 Selenium results in decreased activity of TERT protein CTD PMID:17948765 selenium atom multiple interactions ISO RGD:70505 6480464 [Benzene co-treated with Selenium] results in increased activity of TERT protein CTD PMID:19080380 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA] CTD PMID:16600092 selenium atom decreases expression ISO RGD:1353510 6480464 Selenium results in decreased expression of TERT mRNA CTD PMID:17948765 serpentine asbestos increases response to substance ISO RGD:1353510 6480464 TERT protein results in increased susceptibility to Asbestos, Serpentine CTD PMID:15182483 silicon dioxide increases expression ISO RGD:1353510 6480464 Silicon Dioxide analog results in increased expression of TERT mRNA CTD PMID:25895662 sirolimus decreases expression ISO RGD:1353510 6480464 Sirolimus results in decreased expression of TERT mRNA, Sirolimus results in decreased expression of TERT protein CTD PMID:12939469 more ... sodium arsenite decreases activity ISO RGD:1353510 6480464 sodium arsenite results in decreased activity of TERT protein CTD PMID:22199297 sodium arsenite increases methylation ISO RGD:1353510 6480464 sodium arsenite results in increased methylation of TERT gene CTD PMID:25199682 sodium arsenite increases expression ISO RGD:1353510 6480464 sodium arsenite results in increased expression of TERT mRNA CTD PMID:19337508 , PMID:19464579 sodium arsenite decreases expression ISO RGD:1353510 6480464 sodium arsenite results in decreased expression of TERT mRNA, sodium arsenite results in decreased expression of TERT protein CTD PMID:16966277 more ... sodium dodecyl sulfate decreases expression ISO RGD:1353510 6480464 Sodium Dodecyl Sulfate results in decreased expression of TERT mRNA CTD PMID:17936526 sphingosine affects activity ISO RGD:1353510 6480464 Sphingosine affects the activity of TERT protein CTD PMID:9434777 stanozolol increases activity EXP 6480464 Stanozolol results in increased activity of TERT protein CTD PMID:29717770 staurosporine decreases activity ISO RGD:1353510 6480464 Staurosporine results in decreased activity of TERT protein CTD PMID:9434777 succimer multiple interactions ISO RGD:1353510 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of TERT mRNA CTD PMID:26378955 sulforaphane decreases expression ISO RGD:1353510 6480464 sulforafan results in decreased expression of TERT mRNA CTD PMID:26833863 tamoxifen multiple interactions ISO RGD:1353510 6480464 [Decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Tamoxifen more ... CTD PMID:16051634 more ... tamoxifen decreases expression ISO RGD:1353510 6480464 Tamoxifen results in decreased expression of TERT mRNA alternative form CTD PMID:19501078 temozolomide decreases response to substance ISO RGD:1353510 6480464 TERT protein mutant form results in decreased susceptibility to temozolomide CTD PMID:12488552 temozolomide multiple interactions ISO RGD:1353510 6480464 3-aminobenzamide inhibits the reaction [TERT protein mutant form results in decreased susceptibility to temozolomide] CTD PMID:12488552 terbufos increases methylation ISO RGD:1353510 6480464 terbufos results in increased methylation of TERT promoter CTD PMID:22847954 testosterone multiple interactions ISO RGD:1353510 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of TERT mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1353510 6480464 Testosterone results in decreased expression of TERT mRNA CTD PMID:21592394 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TERT mRNA] CTD PMID:31150632 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of TERT mRNA CTD PMID:31150632 trichostatin A affects expression ISO RGD:1353510 6480464 trichostatin A affects the expression of TERT mRNA, trichostatin A affects the expression of TERT protein CTD PMID:16051188 troglitazone decreases expression ISO RGD:1353510 6480464 troglitazone results in decreased expression of TERT mRNA CTD PMID:20650001 urethane multiple interactions ISO RGD:70505 6480464 Urethane results in increased activity of [TERC protein binds to TEP1 protein binds to TERT protein] CTD PMID:11323394 urethane decreases expression ISO RGD:1353510 6480464 Urethane results in decreased expression of TERT mRNA CTD PMID:28818685 urethane increases expression ISO RGD:70505 6480464 Urethane results in increased expression of TERT mRNA CTD PMID:11323394 valproic acid increases methylation ISO RGD:1353510 6480464 Valproic Acid results in increased methylation of TERT gene CTD PMID:29154799 vitamin E multiple interactions ISO RGD:1353510 6480464 alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased activity of TERT protein] CTD PMID:20112180 wortmannin multiple interactions ISO RGD:1353510 6480464 Wortmannin inhibits the reaction [Camptothecin results in increased phosphorylation of TERT protein] CTD PMID:30851366 zidovudine decreases activity ISO RGD:1353510 6480464 Zidovudine results in decreased activity of TERT protein CTD PMID:16601281 , PMID:18097608 zinc dichloride multiple interactions ISO RGD:1353510 6480464 [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT protein CTD PMID:16624386
Gene-Chemical Interaction Annotations
