Gene: Kit (KIT proto-oncogene receptor tyrosine kinase) Rattus norvegicus
Symbol: Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Description: ENCODES a protein that exhibits protein tyrosine kinase activity; cytokine binding (ortholog); protease binding (ortholog); INVOLVED IN epithelial cell proliferation; germ cell migration; peptidyl-tyrosine phosphorylation; PARTICIPATES IN acute myeloid leukemia pathway; cytokine mediated signaling pathway; endocytosis pathway; ASSOCIATED WITH abnormal interstitial cell of Cajal morphology; absent mast cells; belly spot; ASSOCIATED WITH Anemia, Aplastic; Gastric Reperfusion Injury; Gastroschisis; FOUND IN acrosomal vesicle; cytoplasm; cytoplasmic side of plasma membrane; INTERACTS WITH 2,5-hexanedione; 2-acetamidofluorene; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: c-kit receptor tyrosine kinase; Kit oncogene; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; protein kinase; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Homo sapiens (human) : KIT (KIT proto-oncogene receptor tyrosine kinase)  HGNC  AGR
Mus musculus (house mouse) : Kit (KIT proto-oncogene receptor tyrosine kinase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Kit (KIT proto-oncogene receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : KIT (KIT proto-oncogene receptor tyrosine kinase)
Canis lupus familiaris (dog) : KIT (KIT proto-oncogene receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kit (KIT proto-oncogene receptor tyrosine kinase)
more info ...
Allele / Splice: KitWs  
Genetic Models: BN-KitWs
Is Marker For: Strains:   F344-TyrCKitH/Kyo   F344-AsipATyrCKitH/Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01435,072,131 - 35,149,638 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01434,901,860 - 34,979,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41434,906,043 - 34,984,819 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11434,906,042 - 34,984,819 (-)NCBI
Celera1431,837,543 - 31,913,518 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kit
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620568
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE