GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kit | decreases expression | ISO | KIT (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of KIT mRNA; Arsenic Trioxide results in decreased expression of KIT protein modified form | PMID:19619438 PMID:23815908 PMID:27793025 | Kit | decreases expression | ISO | Kit (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of KIT protein | PMID:20609355 | Kit | decreases phosphorylation | ISO | KIT (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased phosphorylation of KIT protein | PMID:19950550 | Kit | increases expression | ISO | KIT (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of KIT mRNA | PMID:26705709 | Kit | multiple interactions | ISO | KIT (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide promotes the reaction [[GLI3 protein binds to KIT promoter] which results in decreased expression of KIT mRNA]; Arsenic Trioxide promotes the reaction [GLI3 protein binds to KIT promoter] | PMID:27793025 | | ||||||||||||||||||||||
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