KIT (KIT proto-oncogene, receptor tyrosine kinase) - Rat Genome Database

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Gene: KIT (KIT proto-oncogene, receptor tyrosine kinase) Canis lupus familiaris
Analyze
Symbol: KIT
Name: KIT proto-oncogene, receptor tyrosine kinase (Ensembl:KIT proto-onco, receptor tyrosine kinase)
RGD ID: 12090012
Description: ENCODES a protein that exhibits cytokine binding (ortholog); protein tyrosine kinase activity (ortholog); transmembrane receptor protein tyrosine kinase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell chemotaxis (ortholog); cell population proliferation (ortholog); ASSOCIATED WITH white spotting; ASSOCIATED WITH gastrointestinal stromal tumor; Acute Liver Failure (ortholog); acute myeloid leukemia (ortholog); FOUND IN acrosomal vesicle (ortholog); cytoplasmic side of plasma membrane (ortholog); external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: c-KIT; c-KIT gene1; KIT proto-oncogene receptor tyrosine kinase; mast/stem cell growth factor receptor Kit; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; SCFR; tyrosine-protein kinase Kit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11347,108,442 - 47,190,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1347,108,504 - 47,190,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1347,065,096 - 47,146,648 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01347,717,855 - 47,799,689 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1347,717,897 - 47,801,313 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11347,394,247 - 47,475,763 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01346,922,748 - 47,004,082 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01347,870,472 - 47,952,050 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Liver Failure  (ISO)
acute myeloid leukemia  (ISO)
acute pancreatitis  (ISO)
acute promyelocytic leukemia  (ISO)
aplastic anemia  (ISO)
Breast Neoplasms  (ISO)
cholangiocarcinoma  (ISO)
chronic myelogenous leukemia, BCR-ABL1 positive  (ISO)
congenital disorder of glycosylation type IIk  (ISO)
Constipation  (ISO)
cutaneous mastocytosis  (ISO)
diffuse cutaneous mastocytosis  (ISO)
disease of cellular proliferation  (ISO)
dysgerminoma  (ISO)
endometrial stromal sarcoma  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
gastric adenocarcinoma  (ISO)
Gastric Reperfusion Injury  (ISO)
Gastrointestinal Neoplasms  (ISO)
gastrointestinal stromal tumor  (IAGP,ISO)
gastroschisis  (ISO)
genetic disease  (ISO)
Germ Cell and Embryonal Neoplasms  (ISO)
granulosa cell tumor  (ISO)
head and neck squamous cell carcinoma  (ISO)
hematologic cancer  (ISO)
Hematologic Neoplasms  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
Hirschsprung's disease  (ISO)
ileus  (ISO)
interstitial lung disease  (ISO)
invasive ductal carcinoma  (ISO)
Latent Tuberculosis  (ISO)
leiomyosarcoma  (ISO)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
macrocytic anemia  (ISO)
male infertility  (ISO)
malignant mesothelioma  (ISO)
mast-cell leukemia  (ISO)
mastocytosis  (ISO)
melanoma  (ISO)
myeloproliferative neoplasm  (ISO)
Neoplasm Recurrence, Local  (ISO)
nephroblastoma  (ISO)
neurofibroma  (ISO)
ovarian cancer  (ISO)
Ovarian Neoplasms  (ISO)
oxyphilic adenoma  (ISO)
Phyllodes Tumor  (ISO)
piebaldism  (ISO)
primary immunodeficiency disease  (ISO)
Primitive Peripheral Neuroectodermal Tumors  (ISO)
renal cell carcinoma  (ISO)
schizophrenia  (ISO)
seminoma  (ISO)
skin melanoma  (ISO)
systemic mastocytosis  (ISO)
testicular cancer  (ISO)
testicular germ cell cancer  (ISO)
Testicular Germ Cell Tumor  (ISO)
thymoma  (ISO)
Transplant Rejection  (ISO)
urinary bladder cancer  (ISO)
urticaria pigmentosa  (ISO)
uterine carcinosarcoma  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IEA,ISS)
axon guidance  (IEA)
B cell differentiation  (IBA,IEA)
cell chemotaxis  (IEA,ISS)
cell population proliferation  (IEA,ISO)
cell surface receptor protein tyrosine kinase signaling pathway  (IEA)
cytokine-mediated signaling pathway  (IEA,ISO,ISS)
dendrite self-avoidance  (IEA)
detection of mechanical stimulus involved in sensory perception of sound  (IEA,ISS)
developmental pigmentation  (IEA,ISO)
digestive tract development  (IEA,ISS)
ectopic germ cell programmed cell death  (IEA,ISO)
embryonic hemopoiesis  (IEA,ISS)
epithelial cell proliferation  (ISO)
erythrocyte differentiation  (IEA,ISS)
erythropoietin-mediated signaling pathway  (IEA,ISS)
Fc receptor signaling pathway  (IEA,ISS)
germ cell migration  (ISO)
glycosphingolipid metabolic process  (IEA,ISO)
hematopoietic progenitor cell differentiation  (IBA,IEA)
hematopoietic stem cell migration  (IEA,ISO)
hemopoiesis  (IEA,ISO)
homophilic cell adhesion via plasma membrane adhesion molecules  (IEA)
immature B cell differentiation  (IEA,ISS)
inflammatory response  (IEA,ISS)
intracellular signal transduction  (IEA,ISO)
Kit signaling pathway  (IBA,IEA,ISS)
lamellipodium assembly  (IEA,ISS)
lymphoid progenitor cell differentiation  (IEA,ISO)
male gonad development  (IEA)
mast cell chemotaxis  (IEA)
mast cell degranulation  (IEA,ISS)
mast cell differentiation  (IEA,ISO,ISS)
mast cell proliferation  (IEA,ISO)
megakaryocyte development  (IEA,ISS)
melanocyte adhesion  (IEA,ISS)
melanocyte differentiation  (IEA,ISS)
melanocyte migration  (IEA,ISS)
myeloid progenitor cell differentiation  (IEA,ISO)
negative regulation of developmental process  (IEA,ISO)
negative regulation of programmed cell death  (IEA,ISO)
negative regulation of reproductive process  (IEA,ISO)
ovarian follicle development  (IEA,ISS)
peptidyl-tyrosine phosphorylation  (ISO)
pigmentation  (IEA,ISO,ISS)
positive regulation of cell migration  (IBA,IEA,ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of colon smooth muscle contraction  (ISO)
positive regulation of dendritic cell cytokine production  (IEA,ISS)
positive regulation of gene expression  (IEA,ISO)
positive regulation of long-term neuronal synaptic plasticity  (ISO)
positive regulation of MAPK cascade  (IEA)
positive regulation of mast cell cytokine production  (IEA,ISS)
positive regulation of mast cell proliferation  (IEA,ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of pseudopodium assembly  (ISO)
positive regulation of pyloric antrum smooth muscle contraction  (ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (IBA,IEA)
positive regulation of small intestine smooth muscle contraction  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (IEA)
positive regulation of vascular associated smooth muscle cell differentiation  (IEA)
programmed cell death  (IEA,ISO)
protein autophosphorylation  (ISO)
regulation of bile acid metabolic process  (ISO)
regulation of cell shape  (IEA,ISS)
response to cadmium ion  (ISO)
response to radiation  (IEA,ISO)
somatic stem cell population maintenance  (ISO)
spermatid development  (IEA,ISO)
spermatogenesis  (IEA,ISO,ISS)
stem cell differentiation  (IEA,ISS)
T cell differentiation  (IEA,ISS)
tongue development  (ISO)
visual learning  (ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
white spotting  (IAGP)
References
Additional References at PubMed
PMID:9989791   PMID:10210327   PMID:16579858   PMID:16611403   PMID:17491070   PMID:18608529   PMID:18644978   PMID:18977066   PMID:20685234   PMID:20950418   PMID:21160022   PMID:21480930  
PMID:21615421   PMID:21848624   PMID:22235799   PMID:22301074   PMID:22407004   PMID:22747577   PMID:22935087   PMID:23069279   PMID:23294979   PMID:23375718   PMID:23384436   PMID:23659249  
PMID:23791075   PMID:25965812   PMID:26074249   PMID:26412531   PMID:26631948   PMID:27422008   PMID:27815356   PMID:28058543   PMID:28765927   PMID:30032202   PMID:30971355   PMID:31345575  
PMID:32926564   PMID:33827546   PMID:33910439  


Genomics

Comparative Map Data
KIT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11347,108,442 - 47,190,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1347,108,504 - 47,190,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1347,065,096 - 47,146,648 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01347,717,855 - 47,799,689 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1347,717,897 - 47,801,313 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11347,394,247 - 47,475,763 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01346,922,748 - 47,004,082 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01347,870,472 - 47,952,050 (+)NCBIUU_Cfam_GSD_1.0
KIT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38454,657,957 - 54,740,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl454,657,267 - 54,740,783 (+)EnsemblGRCh38hg38GRCh38
GRCh37455,524,124 - 55,606,881 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36455,218,852 - 55,301,638 (+)NCBINCBI36Build 36hg18NCBI36
Build 34455,365,088 - 55,447,783NCBI
Celera453,026,240 - 53,109,027 (+)NCBICelera
Cytogenetic Map4q12NCBI
HuRef451,471,979 - 51,554,769 (+)NCBIHuRef
CHM1_1455,559,642 - 55,642,426 (+)NCBICHM1_1
T2T-CHM13v2.0458,146,698 - 58,229,411 (+)NCBIT2T-CHM13v2.0
Kit
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39575,735,647 - 75,817,382 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl575,735,576 - 75,817,382 (+)EnsemblGRCm39 Ensembl
GRCm38575,574,987 - 75,656,722 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl575,574,916 - 75,656,722 (+)EnsemblGRCm38mm10GRCm38
MGSCv37575,971,012 - 76,052,747 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36575,856,721 - 75,938,419 (+)NCBIMGSCv36mm8
Celera572,859,483 - 72,942,690 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map539.55NCBI
Kit
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81432,901,615 - 32,978,895 (-)NCBIGRCr8
mRatBN7.21432,547,459 - 32,624,694 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1432,548,877 - 32,624,652 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1432,908,757 - 32,989,974 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01434,216,558 - 34,297,770 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01432,701,812 - 32,783,026 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01435,072,131 - 35,149,638 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1435,072,108 - 35,149,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01434,901,860 - 34,979,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41434,906,043 - 34,984,819 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11434,906,042 - 34,984,819 (-)NCBI
Celera1431,837,543 - 31,913,518 (-)NCBICelera
Cytogenetic Map14p11NCBI
Kit
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544716,148,605 - 16,226,734 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544716,149,014 - 16,226,151 (-)NCBIChiLan1.0ChiLan1.0
KIT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2375,054,170 - 75,136,975 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1475,258,141 - 75,340,942 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0469,199,543 - 69,282,323 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1475,761,946 - 75,844,473 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl475,761,946 - 75,844,473 (-)Ensemblpanpan1.1panPan2
Kit
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528529,059,916 - 29,135,385 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648217,162,950 - 17,238,274 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648217,162,854 - 17,238,319 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl841,402,043 - 41,493,734 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1841,402,334 - 41,492,306 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2843,550,231 - 43,601,377 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap8p12NCBI
KIT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1713,808,104 - 13,891,003 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl713,808,037 - 13,890,976 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606614,587,172 - 14,670,161 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kit
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476114,733,912 - 14,831,428 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KIT
902 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 3 6 10
Low 5 5 17 6 3 6 6 6 8 6
Below cutoff 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005627968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005627969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005627970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF044249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF099030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF448148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY296484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY313776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY692084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF471023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000003274   ⟹   ENSCAFP00000003042
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1347,108,504 - 47,190,029 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000049830   ⟹   ENSCAFP00000039467
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1347,143,940 - 47,189,870 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021185   ⟹   ENSCAFP00845016654
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1347,717,897 - 47,801,313 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021235   ⟹   ENSCAFP00845016699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1347,717,907 - 47,801,313 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021261   ⟹   ENSCAFP00845016720
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1347,753,161 - 47,801,043 (+)Ensembl
RefSeq Acc Id: NM_001003181   ⟹   NP_001003181
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11347,108,504 - 47,190,029 (+)NCBI
Dog10K_Boxer_Tasha1347,065,096 - 47,146,648 (+)NCBI
ROS_Cfam_1.01347,717,927 - 47,799,292 (+)NCBI
UMICH_Zoey_3.11347,394,247 - 47,475,763 (+)NCBI
UNSW_CanFamBas_1.01346,922,748 - 47,004,082 (+)NCBI
UU_Cfam_GSD_1.01347,870,472 - 47,952,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038684523   ⟹   XP_038540451
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01347,717,855 - 47,799,689 (+)NCBI
RefSeq Acc Id: XM_038684524   ⟹   XP_038540452
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01347,717,855 - 47,799,689 (+)NCBI
RefSeq Acc Id: XM_038684525   ⟹   XP_038540453
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01347,717,855 - 47,799,689 (+)NCBI
RefSeq Acc Id: NP_001003181   ⟸   NM_001003181
- Peptide Label: precursor
- UniProtKB: Q9XS93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000039467   ⟸   ENSCAFT00000049830
RefSeq Acc Id: ENSCAFP00000003042   ⟸   ENSCAFT00000003274
RefSeq Acc Id: XP_038540451   ⟸   XM_038684523
- Peptide Label: isoform X1
- UniProtKB: Q7YRV7 (UniProtKB/Swiss-Prot),   O97799 (UniProtKB/Swiss-Prot),   Q8WN23 (UniProtKB/Swiss-Prot),   Q9XS93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038540452   ⟸   XM_038684524
- Peptide Label: isoform X2
- UniProtKB: Q9XS93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038540453   ⟸   XM_038684525
- Peptide Label: isoform X3
- UniProtKB: Q9XS93 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845016720   ⟸   ENSCAFT00845021261
RefSeq Acc Id: ENSCAFP00845016654   ⟸   ENSCAFT00845021185
RefSeq Acc Id: ENSCAFP00845016699   ⟸   ENSCAFT00845021235
Protein Domains
Ig-like   Ig-like C2-type   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002065 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00030018961 UniProtKB/Swiss-Prot
  ENSCAFG00040015724 UniProtKB/Swiss-Prot
  ENSCAFG00805007236 UniProtKB/Swiss-Prot
  ENSCAFG00845011904 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003274.5 UniProtKB/Swiss-Prot
  ENSCAFT00000049830.4 UniProtKB/TrEMBL
  ENSCAFT00000107294.1 UniProtKB/TrEMBL
  ENSCAFT00030034940.1 UniProtKB/Swiss-Prot
  ENSCAFT00040028950.1 UniProtKB/Swiss-Prot
  ENSCAFT00805013305 UniProtKB/Swiss-Prot
  ENSCAFT00845021185 ENTREZGENE
  ENSCAFT00845021185.1 UniProtKB/Swiss-Prot
  ENSCAFT00845021235.1 UniProtKB/TrEMBL
  ENSCAFT00845021261 ENTREZGENE
  ENSCAFT00845021261.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCGF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_rcpt_3_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403811 UniProtKB/Swiss-Prot
NCBI Gene KIT ENTREZGENE
PANTHER IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF SCGF_recepter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrPK_CSF1-R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A075MG40_CANLF UniProtKB/TrEMBL
  A0A8I3NKD1_CANLF UniProtKB/TrEMBL
  A0A8I3NKT9_CANLF UniProtKB/TrEMBL
  A0A8P0NQV3_CANLF UniProtKB/TrEMBL
  A0A8P0PNC1_CANLF UniProtKB/TrEMBL
  KIT_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
  Q32Z52_CANLF UniProtKB/TrEMBL
  Q7YRV7 ENTREZGENE
  Q8WN23 ENTREZGENE
  Q9XS93 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q7YRV7 UniProtKB/Swiss-Prot
  Q8WN23 UniProtKB/Swiss-Prot
VGNC ID VGNC:42422 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 KIT  KIT proto-oncogene, receptor tyrosine kinase    KIT proto-oncogene receptor tyrosine kinase  Symbol and/or name change 5135510 APPROVED