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Strain Registration

Strain: LA-cp/NRll

Symbol: LA-cp/NRll
Strain: LA-cp
Substrain: NRll
RGD ID: 40924661
Citation ID: RRID:RGD_40924661
Ontology ID: RS:0004846
Alleles: Leprcp
Previously known as: f rats; LA-cp/Rll
Type: mutant
Source: Not Available
Origin: This corpulent rat used by Rudolph L Leibel's laboratory was developed at the National Institutes of Health (NIH). It was a congenic strain initially derived by mating a male Koletsky rat that was heterozygous for the corpulent gene (cp/ +) to a female Lister Albany/NIH (LAIN) rat. This congenic carrying the recessive Leprcp (RGD:11570565) identified in in the obese spontaneously hypertensive Koletsky rat.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,294,409 - 116,477,904RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05120,503,475 - 120,682,281RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05124,380,327 - 124,556,585RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45122,320,075 - 122,503,449RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat. Wu-Peng XS, etal., Diabetes. 1997 Mar;46(3):513-8.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-20 LA-cp/NRll    LA-cp/Rll    Symbol and/or name change 68913 APPROVED