Strain Report - Rat Genome Database

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Strain: SD-Cftrem1Sage+/-

Symbol: SD-Cftrem1Sage+/-
Strain: SD-Cftrem1+/Cftrem1-
Substrain: Sage
RGD ID: 14392813
Citation ID: RRID:RGD_14392813
Ontology ID: RS:0004680
Alleles: Cftrem1Sage
Previously known as: CFTR Knockout Rat ; SD- Cftr tm1sage
Type: mutant
Source: Horizon Discovery
Origin: Cftr ZFN knockout rats possess a 16 bp deletion in exon 3 of the Cystic Fibrosis transmembrane conductance regulator (Cftr), resulting in loss of protein expression. This Cftr heterozygous rats exhibited similar bioelectric and other characteristics to wild-type.
Genetic Status: Heterozygous
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2019-03-04)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2446,561,269 - 46,728,759RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0442,693,263 - 42,860,679RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0442,281,040 - 42,448,571RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4443,874,852 - 44,041,870RGD_MAPPER_PIPELINERGSC3.4






References

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-04 SD-Cftrem1Sage+/-    SD-Cftrem1Sage-/-    Symbol updated 68687 APPROVED
2019-03-04 SD-Cftrem1Sage+/-    SD-Cftrem1Sage-/-    Symbol updated 68687 APPROVED