Gene: Exoc4 (exocyst complex component 4) Rattus norvegicus
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Symbol: Exoc4
Name: exocyst complex component 4
Description: ENCODES a protein that exhibits PDZ domain binding; protein-containing complex binding; protein N-terminus binding (ortholog); INVOLVED IN chemical synaptic transmission; establishment of cell polarity; Golgi to transport vesicle transport; PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; ASSOCIATED WITH Meckel syndrome (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cell leading edge; dendritic shaft; endosome; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; cisplatin
AGR Description: Exhibits PDZ domain binding activity; involved in several processes, including Golgi to transport vesicle transport, chemical synaptic transmission, and establishment of cell polarity; localizes to several cellular components, including the cell leading edge, myelin sheath, and neuron projection; colocalizes with the Golgi apparatus and endosome; orthologous to human EXOC4 (exocyst complex component 4).
Merged Description: Exhibits PDZ domain binding activity; involved in several processes, including Golgi to transport vesicle transport, chemical synaptic transmission, and establishment of cell polarity; localizes to several cellular components, including the cell leading edge, myelin sheath, and neuron projection; colocalizes with the Golgi apparatus and endosome; orthologous to human EXOC4 (exocyst complex component 4); PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ALR; augmenter of liver regeneration (ALR) pseudogene; exocyst complex component Sec8; rSec8; Sec8; SEC8-like 1; SEC8-like 1 (S. cerevisiae); Sec8l1; secretory protein SEC8
Orthologs:
Homo sapiens (human) : EXOC4 (exocyst complex component 4)  HGNC  Alliance
Mus musculus (house mouse) : Exoc4 (exocyst complex component 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exoc4 (exocyst complex component 4)
Pan paniscus (bonobo/pygmy chimpanzee) : EXOC4 (exocyst complex component 4)
Canis lupus familiaris (dog) : EXOC4 (exocyst complex component 4)
Sus scrofa (pig) : EXOC4 (exocyst complex component 4)
more info ...
Allele / Splice: Exoc4Tn(sb-T2/Bart3)2.317Mcwi  
Genetic Models: F344-Exoc4Tn(sb-T2/Bart3)2.317Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0460,549,128 - 61,358,305 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0460,287,465 - 60,839,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0460,913,238 - 61,081,401 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4460,406,942 - 61,284,294 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1460,683,071 - 61,559,840 (+)NCBI
Celera456,882,713 - 57,637,636 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Exoc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621791
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.