Gene: Exoc4 (exocyst complex component 4) Rattus norvegicus
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Symbol: Exoc4
Name: exocyst complex component 4
Description: ENCODES a protein that exhibits PDZ domain binding; protein-containing complex binding; protein N-terminus binding (ortholog); INVOLVED IN chemical synaptic transmission; establishment of cell polarity; Golgi to transport vesicle transport; PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; ASSOCIATED WITH Meckel syndrome (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cell leading edge; dendritic shaft; endosome; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; cisplatin
AGR Description: Exhibits PDZ domain binding activity; involved in several processes, including Golgi to transport vesicle transport, chemical synaptic transmission, and establishment of cell polarity; localizes to several cellular components, including the cell leading edge, myelin sheath, and neuron projection; colocalizes with the Golgi apparatus and endosome; orthologous to human EXOC4 (exocyst complex component 4).
Merged Description: Exhibits PDZ domain binding activity; involved in several processes, including Golgi to transport vesicle transport, chemical synaptic transmission, and establishment of cell polarity; localizes to several cellular components, including the cell leading edge, myelin sheath, and neuron projection; colocalizes with the Golgi apparatus and endosome; orthologous to human EXOC4 (exocyst complex component 4); PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ALR; augmenter of liver regeneration (ALR) pseudogene; exocyst complex component Sec8; rSec8; Sec8; SEC8-like 1; SEC8-like 1 (S. cerevisiae); Sec8l1; secretory protein SEC8
Orthologs:
Homo sapiens (human) : EXOC4 (exocyst complex component 4)  HGNC  Alliance
Mus musculus (house mouse) : Exoc4 (exocyst complex component 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exoc4 (exocyst complex component 4)
Pan paniscus (bonobo/pygmy chimpanzee) : EXOC4 (exocyst complex component 4)
Canis lupus familiaris (dog) : EXOC4 (exocyst complex component 4)
Sus scrofa (pig) : EXOC4 (exocyst complex component 4)
more info ...
Allele / Splice: Exoc4Tn(sb-T2/Bart3)2.317Mcwi  
Genetic Models: F344-Exoc4Tn(sb-T2/Bart3)2.317Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0460,549,128 - 61,358,305 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0460,287,465 - 60,839,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0460,913,238 - 61,081,401 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4460,406,942 - 61,284,294 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1460,683,071 - 61,559,840 (+)NCBI
Celera456,882,713 - 57,637,636 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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QTLs in Region (Rnor_6.0)
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Sequence

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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Exoc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621791
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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