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Strain: SDR/Slc

Symbol: SDR/Slc
Strain: SDR
Substrain: Slc
Full Name: Spontaneous dwarf rat
RGD ID: 1302698
RRID: RGD_1302698
Ontology ID: RS:0000708
Alleles: Gh1sdr
Also known as: NBRP Rat No: 0151; RRRC:0066
Type: mutant
Source: National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Origin: The G to A substitution at the end of the 3rd intron of the rat Growth hormone gene was identified as the cause of the dwarf phenotype. This spontaneous mutation affected the 3' splice/acceptor site. Strain is from Japan SLC, Inc., Shizuoka, Japan.
Coat Color: Albino
Inbred Generations: F10
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-05-04)
Research Usage Metabolism
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01094,486,204 - 94,488,181RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01094,237,414 - 94,239,391RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41095,692,240 - 95,694,117RGD_MAPPER_PIPELINERGSC3.4





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Mammalian Phenotype

References


Region

Rat Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type
Gh1sdrv-var1 chr10 94486878 94486878 C T point_mutation

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem No immunoreactive GH cells were detected by immunocytochemistry in the pituitary gland. 1578505

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-09 SDR/Slc  Spontaneous dwarf rat  SDR/Slc  Spontaneous dwarf rat  Name updated 68913 APPROVED
2012-04-18 SDR/Slc  Spontaneous dwarf rat  SDR/Slc  Spontaneous dwarf rat  Name updated 68913 APPROVED