Strain: SD-Rag2em1Sage

Symbol: SD-Rag2em1Sage
Strain: SD-Rag2em1
Substrain: Sage
Ontology ID: RS:0004445
Alleles: Rag2em1Sage
Also known as: TGRS4410 ; Rag2 Knockout Rat (Sprague-Dawley) ; SD- Rag2 tm1sage; SD-Rag2em1Sage
Type: mutant
Source: Horizon Discovery
Origin: This ZFN model carries a 2 bp deletion within exon 3 of the Rag2 gene on chromosome 3. Homozygous Rag2 knockout rats display loss of RAG2 protein via Western blot. Homozygous Rag2 knockout rats show loss of B and T cells by FACS analysis.
Genetic Status: Homozygous
Last Known Status: Live Animals (as of 2017-05-24)
Research Usage immunology/Inflamation and Immunodeficient
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0391,191,837 - 91,200,134RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0397,851,318 - 97,859,615RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4386,764,810 - 86,773,438RGD_MAPPER_PIPELINERGSC3.4

Experimental Data Annotations
References - curated


Additional Information

More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 12904903
Created: 2017-05-24
Species: Rattus norvegicus
Last Modified: 2017-05-24
Status: ACTIVE