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Strain: F344-Prkdcem1Kyo

Symbol: F344-Prkdcem1Kyo
Strain: F344-Prkdcem1
Substrain: Kyo
RGD ID: 11040946
Citation ID: RRID:RGD_11040946
Ontology ID: RS:0004134
Alleles: Prkdcem1Kyo;   Prkdc
Also Known As: SCID; F344-Prkdcem1Kyo; NBRP Rat No: 0646; F344-Prkdc^[em1Kyo]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: This strain was established by Zinc-finger nucleases (ZFNs) method taregting exon1 of rat Prkdc gene, resulting a 46-deletion. Background strain: F344/Stm
Coat Color: Albino
Inbred Generations: F3
Last Known Status: Cryopreserved Sperm (as of 2017-06-08)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21185,040,790 - 85,258,357RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01189,293,547 - 89,510,948RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01192,347,175 - 92,565,022RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41186,951,420 - 87,169,229RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Generation and characterization of severe combined immunodeficiency rats. Mashimo T, etal., Cell Rep. 2012 Sep 27;2(3):685-94. doi: 10.1016/j.celrep.2012.08.009. Epub 2012 Sep 13.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain shows severe combined immunodeficiency_SCID_ caused by a 46-bp deletion in the exon 1 of Prkdc gene. 1302502
strain_reproduction maintained by breeding between homozygous rats 1302502