Gene: Lama2 (laminin subunit alpha 2) Rattus norvegicus
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Symbol: Lama2
Name: laminin subunit alpha 2
Description: ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN Schwann cell differentiation; axon guidance (ortholog); positive regulation of synaptic transmission, cholinergic (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; dilated cardiomyopathy pathway; ASSOCIATED WITH renovascular hypertension; Thyroid Neoplasms; autosomal recessive limb-girdle muscular dystrophy 23 (ortholog); FOUND IN basement membrane; dendritic spine; neuromuscular junction (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; atrazine; bisphenol A
AGR Description: Predicted to have signaling receptor binding activity; involved in Schwann cell differentiation; localizes to the basement membrane and dendritic spine; biomarker of renovascular hypertension; orthologous to human LAMA2 (laminin subunit alpha 2).
Merged Description: Predicted to have signaling receptor binding activity; involved in Schwann cell differentiation; localizes to the basement membrane and dendritic spine; biomarker of renovascular hypertension; orthologous to human LAMA2 (laminin subunit alpha 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; dilated cardiomyopathy pathway; INTERACTS WITH 17alpha-ethynylestradiol; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: laminin subunit alpha-2; laminin, alpha 2; LOC309368
Orthologs:
Homo sapiens (human) : LAMA2 (laminin subunit alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : Lama2 (laminin, alpha 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama2 (laminin subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMA2 (laminin subunit alpha 2)
Canis lupus familiaris (dog) : LAMA2 (laminin subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama2 (laminin subunit alpha 2)
Sus scrofa (pig) : LAMA2 (laminin subunit alpha 2)
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Allele / Splice: Lama2Tn(sb-T2/Bart3)2.2013Mcwi  
Genetic Models: F344-Lama2Tn(sb-T2/Bart3)2.2013Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0118,491,264 - 19,143,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0120,002,787 - 20,647,256 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4118,203,466 - 18,885,462 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1118,324,930 - 18,885,310 (+)NCBI
Celera116,078,601 - 16,724,118 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
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Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Lama2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308889
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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