Strain: SD-Apoeem1Sage

Symbol: SD-Apoeem1Sage
Strain: SD-Apoeem1
Substrain: Sage
Ontology ID: RS:0004423
Alleles: Apoeem1Sage
Also known as: SD- ApoE tm1sage; TGRA3710
Type: mutant
Source: Horizon Discovery
Origin: The mutant rat strain was produced by injecting zinc endonuclease targeting the exon 3 of rat Apoe into Sprague Dawley embryos. This mutant rat has a 16-bp deletion in the gene and resulted in complete loss of Apoe protein in homozygotes.
Genetic Status: Homozygous
Last Known Status: Live Animals (as of 2017-05-01)
Research Usage Alzheimer's disease, Neurodegenerative diseases
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,612,894 - 80,616,820RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0181,878,372 - 81,882,298RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4179,003,634 - 79,006,387RGD_MAPPER_PIPELINERGSC3.4

Experimental Data Annotations
References - curated


Additional Information

More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 12880021
Created: 2017-05-01
Species: Rattus norvegicus
Last Modified: 2017-05-01
Status: ACTIVE