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Strain: F344-Bscl2m1Kyo

Symbol: F344-Bscl2m1Kyo
Strain: F344-Bscl2m1
Substrain: Kyo
RGD ID: 11040962
Citation ID: RRID:RGD_11040962
Ontology ID: RS:0004148
Alleles: Bscl2m1Kyo;   Bscl2
Also known as: F344-Bscl2m1Kyo; SKOrat; NBRP Rat No: 0763; Bscl2sko/sko
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: T239A mutation was found by screening of 4608DNA sample from ENU mutagenesis library KURMA. This strain has a T239A (L80X) nonsense mutation in Bscl2 gene.
Genetic Status: Homozygous
Inbred Generations: N10
Last Known Status: Cryopreserved Sperm (as of 2019-01-09)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21205,731,814 - 205,743,430RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01225,035,956 - 225,046,137RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01231,972,073 - 231,983,764RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41211,509,675 - 211,518,963RGD_MAPPER_PIPELINERGSC3.4



Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Bscl2T239A homozygous mutated rat shows severe atrophy of adipose tissue, hypoleptinemia, abnormal glucose tolerance, increment of triglyceride levels in the liver. Bscl2T239A mutated male rats have small testes with sperm hypoplasia and are infertile. 1302502
strain_reproduction crossing between heterozygous rats 1302502