Gene: F8 (coagulation factor VIII) Rattus norvegicus
Analyze
Symbol:
F8
Name:
coagulation factor VIII
Description:
Predicted to have copper ion binding activity and oxidoreductase activity. Involved in blood coagulation, intrinsic pathway. Localizes to the extracellular space. Used to study factor VIII deficiency and hyperhomocysteinemia. Human ortholog(s) of this gene implicated in factor VIII deficiency. Orthologous to human F8 (coagulation factor VIII); PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
coagulation factor VIII, procoagulant component
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
F8 (coagulation factor VIII) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
F8 (coagulation factor VIII) HGNC
Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
F8 (coagulation factor VIII) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
F8 (coagulation factor VIII) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
F8 (coagulation factor VIII) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
F8 (coagulation factor VIII) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
F8 (coagulation factor VIII) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
F8 (coagulation factor VIII)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
F8 (coagulation factor VIII)
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
f8 (coagulation factor VIII, procoagulant component)
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER)
Allele / Splice:
F8m1Ycb
F8em1Sage
F8em1Mcwi
Genetic Models:
SD/Novo-F8em1Sage-/-
SD/Novo-F8em1Sage
SD/Novo-F8em1Sage+/-
SS-F8em1Mcwi
WAG-F8m1Ycb
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 18 367,862 - 399,242 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 18 367,862 - 399,242 (-) Ensembl Rnor_5.0 18 413,447 - 444,491 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 18 121,134 - 162,008 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 18 121,133 - 162,008 (+) NCBI Celera 18 135,235 - 166,779 (+) NCBI Celera Cytogenetic Map 18 p13 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
adrenoleukodystrophy ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Adrenoleukodystrophy ClinVar PMID:28492532 autistic disorder ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Autistic disorder of childhood onset ClinVar PMID:21681106 , PMID:30208311 blood coagulation disease ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Blood coagulation disorder ClinVar PMID:25741868 blood coagulation disease ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Blood coagulation disorder ClinVar PMID:25741868 , PMID:8485051 blood coagulation disease ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Blood coagulation disorder ClinVar PMID:1301932 , PMID:25741868 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1924291 , PMID:6438527 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1301932 , PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1908096 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1349567 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:2104741 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1924291 , PMID:25741868 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:25741868 , PMID:8485051 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1301932 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:25741868 , PMID:2987704 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: FACTOR VIII (OKAYAMA) ClinVar PMID:2498882 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:25741868 , PMID:8307558 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1301932 , PMID:25741868 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1924291 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1301932 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1569180 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1908096 , PMID:25741868 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:2986011 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:2901224 , PMID:3097553 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1924291 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:25741868 , PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:1301932 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:25741868 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:24033266 , PMID:25741868 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1908096 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1357455 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1924291 , PMID:8281136 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1979502 , PMID:8281136 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1349567 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8281136 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:6438527 , PMID:8281136 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:2493803 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:25741868 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1639429 , PMID:8307558 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:6438527 , PMID:8497853 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301932 , PMID:6438527 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1523102 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1643024 , PMID:3035554 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:11713379 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:7662970 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1969840 , PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301932 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2159433 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2835307 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2901224 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2495245 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2861360 , PMID:3097553 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8322269 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:12351418 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1923751 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1643024 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2831458 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:12406074 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2121641 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8054459 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2907841 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1559571 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1908096 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2887317 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2105106 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2861360 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2110545 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2105906 , PMID:2107542 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1979502 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301932 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2833855 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1908096 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8485051 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2107542 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1412186 , PMID:1908096 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8052958 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2473810 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2106480 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1569180 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2105906 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1349567 , PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1639429 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8307558 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8497853 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2110545 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1349567 , PMID:1979502 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1924291 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:3122181 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2833855 , PMID:3131627 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:11110718 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1523102 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1840568 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A, FVIII Deficiency ClinVar PMID:17209060 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A, FVIII Deficiency ClinVar PMID:15921397 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia A ClinVar PMID:10910913 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8069313 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2987704 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2510835 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1924291 , PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1908096 , PMID:7728145 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301194 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1412186 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2109644 , PMID:2506948 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301932 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:3097553 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:8449505 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2833855 , PMID:6253938 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1349567 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301960 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301932 , PMID:8307558 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2104741 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1301932 more ... factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:1908817 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:3035554 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:2125022 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:6438527 , PMID:8307558 factor VIII deficiency ISO RGD:1343567 8554872 ClinVar Annotator: match by OMIM:306700 ClinVar PMID:6438527 , PMID:7728145 genetic disease ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1908096 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1301932 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1301932 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:25741868 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1908096 , PMID:25741868 hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1924291 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1301932 , PMID:25741868 hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:2498882 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:2104741 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:25741868 hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:25741868 , PMID:7728145 hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1349567 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:25741868 , PMID:2987704 hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1301932 more ... hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:1924291 , PMID:25741868 hemophilia B ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemophilia B ClinVar PMID:25741868 , PMID:8307558 hemorrhagic disease ISO RGD:1343567 8554872 ClinVar Annotator: match by term: Hemorrhagic diathesis ClinVar PMID:25741868
Gene-Chemical Interaction Annotations
