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Strain Registration

Strain: SS-Agtr1aem5Mcwi

Symbol: SS-Agtr1aem5Mcwi
Strain: SS-Agtr1aem5
Substrain: Mcwi
RGD ID: 5508365
Citation ID: RRID:RGD_5508365
Ontology ID: RS:0002928
Alleles: Agtr1aem5Mcwi
Also Known As: SS-Agtr1aem5Mcwi; SS-Agtr1a^[em5Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CTTTGCCCCTGTGGGCAGtctatACCGCTATGGAGTACCGCT into SS/JrHsdMcwi rat embryos. The resulting mutation is a 19-bp frameshift deletion in exon 3.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21734,173,446 - 34,226,892RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01735,908,756 - 35,908,774RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01737,217,810 - 37,270,540RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41740,629,318 - 40,684,982RGD_MAPPER_PIPELINERGSC3.4

Mutant Strains
SS-Agtr1aem5Mcwi-/-




Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Interaction between Mas1 and AT1RA contributes to enhancement of skeletal muscle angiogenesis by angiotensin-(1-7) in Dahl salt-sensitive rats. Exner EC, etal., PLoS One. 2020 Apr 23;15(4):e0232067. doi: 10.1371/journal.pone.0232067. eCollection 2020.
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Agtr1aem5Mcwi-var1 chr17 35908756 35908774 CCATAGCGGTATAGACTGC - deletion Rnor_6.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Agtr1aem5Mcwi    SS-Agtr1aem5Mcwi    Name updated 68913 APPROVED
2014-03-26 SS-Agtr1aem5Mcwi    SS-Agtr1aem5Mcwi    Symbol updated 68687 APPROVED
2014-03-26 SS-Agtr1aem5Mcwi    SS-Agtr1aem5Mcwi    Name updated 68913 APPROVED
2014-03-26 SS-Agtr1aem5Mcwi    SS-Agtr1aem5Mcwi    Symbol updated 68687 APPROVED
2013-08-14 SS-Agtr1aem5Mcwi    SS-Agtr1aem5Mcwi    Name updated 68913 APPROVED