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Strain Registration

Strain: LEW.1WR1-Ifnar1em2

Symbol: LEW.1WR1-Ifnar1em2
Strain: LEW.1WR1-Ifnar1em2
RGD ID: 12910494
Citation ID: RRID:RGD_12910494
Ontology ID: RS:0004464
Alleles: Ifnar1em2
Also Known As: Ifnar1-/-LEW.1WR1; LEW.1WR1-Ifnar1em2; IFNAR1delta81+4; LEW.1WR1-Ifnar1^[em2]
Type: mutant
Available Source: Not Available
Origination: Department of Medicine, University of Massachusetts Medical School, Worcester, MA
Description: The CRISPR/Cas9 genome editing system was used to generate this mutant rat strain. The resulting strains carrying a 81-bp deletion and 4-bp insertion in exon 4 of Ifnar1 gene.
Genetic Status: Homozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,725,774 - 30,752,227RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01131,640,407 - 31,666,839RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01135,248,575 - 35,272,235RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41131,454,789 - 31,478,449RGD_MAPPER_PIPELINERGSC3.4





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats. Qaisar N, etal., Diabetes. 2017 Jan;66(1):145-157. doi: 10.2337/db16-0462. Epub 2016 Oct 7.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-26 LEW.1WR1-Ifnar1em2    SD-Ifnar1em2    Symbol updated 68687 APPROVED
2017-06-26 LEW.1WR1-Ifnar1em2    SD-Ifnar1em2    Symbol updated 68687 APPROVED