Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Grm7 (glutamate metabotropic receptor 7) Rattus norvegicus
Analyze
Symbol: Grm7
Name: glutamate metabotropic receptor 7
Description: Exhibits several functions, including PDZ domain binding activity; calmodulin binding activity; and glutamate binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; negative regulation of glutamate secretion; and negative regulation of neuron apoptotic process. Localizes to several cellular components, including the cytoplasm; neuron projection; and synaptic membrane. Orthologous to human GRM7 (glutamate metabotropic receptor 7); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; ammonium chloride; beta-naphthoflavone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glutamate receptor, metabotropic 7; metabotropic glutamate receptor 7; metabotropic glutamate receptor mGluR7; metabotropic glutamate receptor subtype 7b; mGluR7
Orthologs:
Homo sapiens (human) : GRM7 (glutamate metabotropic receptor 7)  HGNC  Alliance
Mus musculus (house mouse) : Grm7 (glutamate receptor, metabotropic 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm7 (glutamate metabotropic receptor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM7 (glutamate metabotropic receptor 7)
Canis lupus familiaris (dog) : GRM7 (glutamate metabotropic receptor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm7 (glutamate metabotropic receptor 7)
Sus scrofa (pig) : GRM7 (glutamate metabotropic receptor 7)
more info ...
Allele / Splice: Grm7em2Mcwi  
Genetic Models: SS-Grm7em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04142,452,616 - 143,368,460 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04206,230,927 - 206,680,107 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04205,768,625 - 206,090,308 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44146,952,340 - 147,270,225 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14146,889,004 - 147,035,543 (-)NCBI
Celera4132,321,261 - 133,197,545 (+)NCBICelera
Cytogenetic Map4q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Grm7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619857
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.