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Gene: GRM4 (glutamate metabotropic receptor 4) Homo sapiens
Symbol: GRM4
Name: glutamate metabotropic receptor 4
RGD ID: 731311
Description: Exhibits G protein-coupled receptor activity and glutamate receptor activity. Involved in activation of MAPK activity and adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway. Localizes to cytoplasmic vesicle and integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutamate receptor, metabotropic 4; GPRC1D; metabotropic glutamate receptor 4; MGC177594; mGlu4; MGLUR4
Mus musculus (house mouse) : Grm4 (glutamate receptor, metabotropic 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Grm4 (glutamate metabotropic receptor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm4 (glutamate metabotropic receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM4 (glutamate metabotropic receptor 4)
Canis lupus familiaris (dog) : GRM4 (glutamate metabotropic receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm4 (glutamate metabotropic receptor 4)
Sus scrofa (pig) : GRM4 (glutamate metabotropic receptor 4)
Heterocephalus glaber (naked mole-rat) : Grm4 (glutamate metabotropic receptor 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl634,018,643 - 34,155,622 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl634,018,645 - 34,155,622 (-)EnsemblGRCh38hg38GRCh38
GRCh38634,018,643 - 34,155,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37633,989,623 - 34,123,399 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36634,097,606 - 34,209,421 (-)NCBINCBI36hg18NCBI36
Build 34634,097,606 - 34,209,421NCBI
Celera635,543,989 - 35,655,835 (-)NCBI
Cytogenetic Map6p21.31NCBI
HuRef633,731,329 - 33,846,092 (-)NCBIHuRef
CHM1_1633,988,493 - 34,125,948 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GRM4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731311
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.