Ngly1 (N-glycanase 1) - Rat Genome Database

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Gene: Ngly1 (N-glycanase 1) Rattus norvegicus
Analyze
Symbol: Ngly1
Name: N-glycanase 1
RGD ID: 1308518
Description: Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Involved in ER-associated misfolded protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Used to study NGLY1-deficiency. Human ortholog(s) of this gene implicated in NGLY1-deficiency. Orthologous to human NGLY1 (N-glycanase 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100909559; LOC289935; LOC361014; peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; peptide:N-glycanase; PNGase; similar to peptide N-glycanase; uncharacterized LOC100909559
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ngly1em1Ta  
Genetic Models: SD-Ngly1em1Ta-/-
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2159,153,738 - 9,210,228 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl159,153,738 - 9,204,630 (-)Ensembl
Rnor_6.01510,405,453 - 10,455,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1510,405,164 - 10,455,956 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01514,450,836 - 14,501,356 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41510,704,196 - 10,750,564 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11510,715,806 - 10,723,084 (-)NCBI
Celera159,192,318 - 9,243,191 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
cytosol  (IBA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12477932   PMID:15057822   PMID:15358861   PMID:15489334   PMID:22871113   PMID:28826503  


Genomics

Comparative Map Data
Ngly1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2159,153,738 - 9,210,228 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl159,153,738 - 9,204,630 (-)Ensembl
Rnor_6.01510,405,453 - 10,455,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1510,405,164 - 10,455,956 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01514,450,836 - 14,501,356 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41510,704,196 - 10,750,564 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11510,715,806 - 10,723,084 (-)NCBI
Celera159,192,318 - 9,243,191 (-)NCBICelera
Cytogenetic Map15p16NCBI
NGLY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38325,718,944 - 25,790,039 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl325,718,944 - 25,790,039 (-)EnsemblGRCh38hg38GRCh38
GRCh37325,760,435 - 25,831,530 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36325,735,779 - 25,799,926 (-)NCBINCBI36hg18NCBI36
Build 34325,735,778 - 25,799,926NCBI
Celera325,697,316 - 25,768,403 (-)NCBI
Cytogenetic Map3p24.2NCBI
HuRef325,705,518 - 25,776,520 (-)NCBIHuRef
CHM1_1325,710,469 - 25,781,508 (-)NCBICHM1_1
T2T-CHM13v2.0325,721,799 - 25,792,805 (-)NCBI
Ngly1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39146,157,837 - 6,220,449 (-)NCBIGRCm39mm39
GRCm39 Ensembl146,157,837 - 6,220,483 (-)Ensembl
GRCm381416,249,314 - 16,311,926 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1416,249,280 - 16,311,926 (+)EnsemblGRCm38mm10GRCm38
MGSCv371417,081,828 - 17,144,440 (+)NCBIGRCm37mm9NCBIm37
MGSCv361415,042,581 - 15,105,193 (+)NCBImm8
Celera1411,944,272 - 12,005,168 (+)NCBICelera
Cytogenetic Map14A1NCBI
cM Map147.08NCBI
Ngly1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543017,564,319 - 17,645,564 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543017,564,319 - 17,645,564 (-)NCBIChiLan1.0ChiLan1.0
NGLY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1325,950,189 - 26,014,998 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl325,950,701 - 26,021,504 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0325,618,768 - 25,683,293 (-)NCBIMhudiblu_PPA_v0panPan3
NGLY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12318,044,479 - 18,101,937 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2318,039,456 - 18,099,660 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2318,042,146 - 18,099,607 (+)NCBI
ROS_Cfam_1.02318,347,625 - 18,405,157 (+)NCBI
ROS_Cfam_1.0 Ensembl2318,342,554 - 18,405,154 (+)Ensembl
UMICH_Zoey_3.12318,166,197 - 18,223,888 (+)NCBI
UNSW_CanFamBas_1.02318,269,312 - 18,326,783 (+)NCBI
UU_Cfam_GSD_1.02318,383,003 - 18,440,512 (+)NCBI
Ngly1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118184,105,190 - 184,155,991 (-)NCBI
SpeTri2.0NW_00493647317,243,763 - 17,294,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NGLY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1312,616,567 - 12,685,823 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11312,616,564 - 12,683,637 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21314,229,512 - 14,291,711 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NGLY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11570,381,992 - 70,449,373 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1570,382,004 - 70,449,341 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604143,521,267 - 43,588,968 (-)NCBIVero_WHO_p1.0
Ngly1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247883,626,893 - 3,707,680 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247883,631,142 - 3,707,725 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BF402481  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2159,179,073 - 9,179,264 (+)MAPPERmRatBN7.2
Rnor_6.01510,430,471 - 10,430,661NCBIRnor6.0
Rnor_5.01514,475,854 - 14,476,044UniSTSRnor5.0
RGSC_v3.41510,729,979 - 10,730,169UniSTSRGSC3.4
Celera159,217,340 - 9,217,530UniSTS
RH 3.4 Map1592.5UniSTS
Cytogenetic Map15p16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15105825014481294Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15226636822711984Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat


Genetic Models
This gene Ngly1 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:38
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000008289
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000008289   ⟹   ENSRNOP00000008289
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl159,153,738 - 9,204,594 (-)Ensembl
Rnor_6.0 Ensembl1510,405,164 - 10,455,956 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104278   ⟹   ENSRNOP00000083143
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl159,153,745 - 9,204,630 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116474   ⟹   ENSRNOP00000086683
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl159,153,738 - 9,204,573 (-)Ensembl
RefSeq Acc Id: NM_001014136   ⟹   NP_001014158
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2159,154,055 - 9,204,621 (-)NCBI
Rnor_6.01510,405,453 - 10,455,973 (-)NCBI
Rnor_5.01514,450,836 - 14,501,356 (-)NCBI
RGSC_v3.41510,704,196 - 10,750,564 (-)RGD
Celera159,192,318 - 9,243,191 (-)RGD
Sequence:
RefSeq Acc Id: XM_039093449   ⟹   XP_038949377
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2159,153,738 - 9,204,657 (-)NCBI
RefSeq Acc Id: XM_039093450   ⟹   XP_038949378
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2159,153,738 - 9,204,658 (-)NCBI
RefSeq Acc Id: XM_039093451   ⟹   XP_038949379
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2159,153,738 - 9,210,228 (-)NCBI
RefSeq Acc Id: XM_039093452   ⟹   XP_038949380
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2159,153,738 - 9,204,657 (-)NCBI
RefSeq Acc Id: XM_039093453   ⟹   XP_038949381
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2159,153,738 - 9,204,601 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001014158   ⟸   NM_001014136
- UniProtKB: Q5XI55 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000008289   ⟸   ENSRNOT00000008289
RefSeq Acc Id: XP_038949379   ⟸   XM_039093451
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038949378   ⟸   XM_039093450
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949380   ⟸   XM_039093452
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038949377   ⟸   XM_039093449
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949381   ⟸   XM_039093453
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000086683   ⟸   ENSRNOT00000116474
RefSeq Acc Id: ENSRNOP00000083143   ⟸   ENSRNOT00000104278
Protein Domains
PAW   PUB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI55-F1-model_v2 AlphaFold Q5XI55 1-651 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699580
Promoter ID:EPDNEW_R10103
Type:multiple initiation site
Name:Ngly1_1
Description:N-glycanase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01510,455,960 - 10,456,020EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308518 AgrOrtholog
BioCyc Gene G2FUF-14430 BioCyc
Ensembl Genes ENSRNOG00000006143 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000008289 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000086683 ENTREZGENE
Ensembl Transcript ENSRNOT00000008289 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000116474 ENTREZGENE
Gene3D-CATH 2.60.120.1020 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7113173 IMAGE-MGC_LOAD
InterPro Galactose-bd-like_sf UniProtKB/Swiss-Prot
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  PAW_sf UniProtKB/Swiss-Prot
  Peptide_N_glycanase_PAW_dom UniProtKB/Swiss-Prot
  PUB-like_dom_sf UniProtKB/Swiss-Prot
  PUB_domain UniProtKB/Swiss-Prot
  Transglutaminase-like UniProtKB/Swiss-Prot
KEGG Report rno:361014 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94949 IMAGE-MGC_LOAD
NCBI Gene 361014 ENTREZGENE
Pfam PAW UniProtKB/Swiss-Prot
  PUB UniProtKB/Swiss-Prot
  Transglut_core UniProtKB/Swiss-Prot
PhenoGen Ngly1 PhenoGen
PROSITE PAW UniProtKB/Swiss-Prot
SMART PAW UniProtKB/Swiss-Prot
  TGc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF143503 UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot
  SSF54001 UniProtKB/Swiss-Prot
UniProt NGLY1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ngly1  N-glycanase 1  LOC100909559  uncharacterized LOC100909559  Data Merged 737654 PROVISIONAL
2012-07-05 LOC100909559  uncharacterized LOC100909559      Symbol and Name status set to provisional 70820 PROVISIONAL
2007-02-07 Ngly1  N-glycanase 1  Ngly1_predicted  N-glycanase 1 (predicted)  Symbol and Name updated 1299863 APPROVED
2007-02-07 Ngly1_predicted  N-glycanase 1 (predicted)  LOC361014  similar to peptide N-glycanase  Data Merged 737654 APPROVED
2006-11-19 LOC361014  similar to peptide N-glycanase      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Ngly1_predicted  N-glycanase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED