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Strain: SD-Hamp em2Jfcol -/-

Symbol: SD-Hamp em2Jfcol -/-
Strain: SD-Hamp em2-/-
Substrain: Jfcol
RGD ID: 36174222
Citation ID: RRID:RRRC_00909
Ontology ID: RS:0005015
Alleles: Hamp em2Jfcol
Also Known As: RRRC:00909; SD-Hamp^[ em2Jfcol -/-]
Type: mutant
Available Source: Rat Resource & Research Center (RRRC)
Description: Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em2Jfcol -/- (RGD:36174222) is homozygous carrying a 230-bp deletion and a 1-bp insertion between exons 2 & 3 of both rat Hamp alleles.
Genetic Status: Homozygous
Last Known Status: Cryopreserved Sperm (as of 2020-07-29)
Research Usage This rat models hereditary hemochromatosis (Type 2B) in humans. Iron overload research.
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,170,926 - 86,172,865RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0189,368,021 - 89,369,960RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0190,523,506 - 90,525,473RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4185,978,120 - 85,980,059RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Strains registered by Jennifer Lee from University of Florida Strains registered by Jennifer Lee from University of Florida


Additional Information

Database Acc Id Source(s)