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Gene: Ubqln4 (ubiquilin 4) Rattus norvegicus

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Symbol:

Ubqln4

Name:

ubiquilin 4

RGD ID:

1308273

Description:

Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of metabolic process; regulation of proteasomal ubiquitin-dependent protein catabolic process; and ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including autophagosome; endoplasmic reticulum membrane; and site of DNA damage. Predicted to be part of cytosolic proteasome complex and nuclear proteasome complex. Predicted to be active in cytosol. Orthologous to human UBQLN4 (ubiquilin 4); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC310633; RGD1308273; similar to UBIN; ubiquilin-4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UBQLN4 (ubiquilin 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ubqln4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ubqln4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UBQLN4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UBQLN4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ubqln4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UBQLN4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UBQLN4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ubqln4 (ubiquilin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	UBQLN4 (ubiquilin 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ubqln4 (ubiquilin 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ubqln4 (ubiquilin 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DSK2	Alliance	DIOPT (InParanoid\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	DSK2	Alliance	DIOPT (InParanoid\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ubql-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ubqn	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ubqln4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Ubqln4^{Tn(sb-T2/Bart3)2.230Mcwi}

Genetic Models:

F344-Ubqln4^{Tn(sb-T2/Bart3)2.230Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	176,310,524 - 176,325,724 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	176,310,568 - 176,325,924 (+)	Ensembl				GRCr8
mRatBN7.2	2	174,012,726 - 174,028,062 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	174,012,777 - 174,028,059 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	181,156,886 - 181,172,060 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	179,179,251 - 179,194,425 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,779,342 - 173,794,732 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,915,701 - 187,931,035 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,915,751 - 187,931,035 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	207,318,101 - 207,333,435 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	180,669,525 - 180,684,724 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	167,957,113 - 167,972,312 (+)	NCBI		Celera
RGSC_v3.1	2	180,619,753 - 180,633,903 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 2 (ISO)

gastrointestinal stromal tumor (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

Noonan syndrome 8 (ISO)

parathyroid carcinoma (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,4-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

caffeine (ISO)

copper atom (EXP)

copper(0) (EXP)

Cuprizon (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethanol (ISO)

flutamide (EXP)

formaldehyde (ISO)

genistein (ISO)

haloperidol (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

Nutlin-3 (ISO)

paracetamol (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sevoflurane (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagy (IEA)

biological_process (ND)

DNA damage response (IEA,ISO)

DNA repair (IEA)

negative regulation of autophagosome maturation (IEA,ISO)

negative regulation of double-strand break repair via homologous recombination (IEA,ISO)

regulation of proteasomal ubiquitin-dependent protein catabolic process (IEA,ISO)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

autophagosome (IEA,ISO)

chromosome (IEA)

cytoplasm (IEA,ISO)

cytoplasmic vesicle (IEA)

cytosol (IBA,IEA,ISO)

cytosolic proteasome complex (IEA,ISO)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA,ISO)

nuclear proteasome complex (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

perinuclear region of cytoplasm (IEA)

protein-containing complex (IEA,ISO)

site of DNA damage (IEA,ISO)

Molecular Function

identical protein binding (IEA,ISO)

K48-linked polyubiquitin modification-dependent protein binding (IEA,ISO)

polyubiquitin modification-dependent protein binding (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Endoplasmic Reticulum-associated degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:11001934	PMID:11162551	PMID:15280365	PMID:16713569	PMID:18079109	PMID:23459205	PMID:27113755	PMID:29666234	PMID:30612738

Genomics

Comparative Map Data

Ubqln4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	176,310,524 - 176,325,724 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	176,310,568 - 176,325,924 (+)	Ensembl				GRCr8
mRatBN7.2	2	174,012,726 - 174,028,062 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	174,012,777 - 174,028,059 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	181,156,886 - 181,172,060 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	179,179,251 - 179,194,425 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,779,342 - 173,794,732 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,915,701 - 187,931,035 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,915,751 - 187,931,035 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	207,318,101 - 207,333,435 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	180,669,525 - 180,684,724 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	167,957,113 - 167,972,312 (+)	NCBI		Celera
RGSC_v3.1	2	180,619,753 - 180,633,903 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

UBQLN4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	156,031,247 - 156,053,798 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	156,035,299 - 156,053,798 (-)	Ensembl			hg38	GRCh38
GRCh37	1	156,005,090 - 156,023,589 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	154,271,716 - 154,290,140 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	152,818,165 - 152,836,589	NCBI
Celera	1	129,078,055 - 129,096,477 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI
HuRef	1	127,367,831 - 127,386,064 (-)	NCBI		HuRef
CHM1_1	1	157,401,172 - 157,419,603 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	155,169,709 - 155,192,264 (-)	NCBI		T2T-CHM13v2.0

Ubqln4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	88,460,984 - 88,477,032 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	88,461,065 - 88,477,032 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	88,553,677 - 88,569,725 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	88,553,758 - 88,569,725 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	88,357,638 - 88,373,647 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	88,639,643 - 88,655,652 (+)	NCBI		MGSCv36	mm8
Celera	3	88,593,533 - 88,609,536 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	38.87	NCBI

Ubqln4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	2,220,548 - 2,236,646 (-)	Ensembl
ChiLan1.0	NW_004955545	2,218,794 - 2,236,665 (-)	NCBI	ChiLan1.0	ChiLan1.0

UBQLN4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	93,792,457 - 93,814,703 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	93,524,402 - 93,545,849 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	131,374,635 - 131,395,986 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	135,209,490 - 135,225,666 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	135,209,490 - 135,225,666 (-)	Ensembl			panPan2	panpan1.1

UBQLN4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	41,764,209 - 41,778,457 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	41,764,253 - 41,777,002 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	41,253,685 - 41,267,979 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	41,630,903 - 41,645,198 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	41,630,863 - 41,645,198 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	41,411,750 - 41,426,044 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	41,465,103 - 41,479,633 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	41,749,531 - 41,763,822 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ubqln4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	26,269,482 - 26,285,374 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	5,301,389 - 5,315,756 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	5,299,864 - 5,316,583 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBQLN4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	93,976,451 - 93,994,828 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	93,976,386 - 93,994,830 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	102,719,204 - 102,737,608 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBQLN4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	7,811,275 - 7,829,782 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	7,107,553 - 7,127,896 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ubqln4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	1,383,897 - 1,398,484 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624885	1,382,302 - 1,398,474 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Ubqln4
65 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	698
Count of miRNA genes:	288
Interacting mature miRNAs:	356
Transcripts:	ENSRNOT00000026994
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
6907363	Bp357	Blood pressure QTL 357	4.1	0.002	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	129540907	174540907	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	152413072	185122374	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	143657411	190602963	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	152413072	185122374	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	152413072	185122374	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	152413072	185122374	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168354880	185122374	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
12879845	Cm89	Cardiac mass QTL 89		0.008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	152413072	175950118	Rat
61473	Bp19	Blood pressure QTL 19	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	172710921	175950118	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	114837527	185876470	Rat
12879846	Cm90	Cardiac mass QTL 90		0.011	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	2	152413072	175950118	Rat
12879847	Am4	Aortic mass QTL 4		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	152413072	175950118	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	152413072	185122374	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	157142078	192625452	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2301415	Cm67	Cardiac mass QTL 67		0.003	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	152413072	175950118	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
11565180	Kidm56	Kidney mass QTL 56		0.003	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	152413072	175950118	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150341585	189039377	Rat
11565181	Bw176	Body weight QTL 176		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	2	152413072	175950118	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	144599348	189599348	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147798556	192798556	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	172710921	184114403	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
6903312	Bw112	Body weight QTL 112	3.2	0.0013	body mass (VT:0001259)	body weight (CMO:0000012)	2	143657569	184114274	Rat
7488904	Bp363	Blood pressure QTL 363		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	172982062	175950118	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat

Markers in Region

RH134224

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	174,027,564 - 174,027,777 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	187,930,538 - 187,930,750	NCBI	Rnor6.0
Rnor_5.0	2	207,332,938 - 207,333,150	UniSTS	Rnor5.0
RGSC_v3.4	2	180,684,362 - 180,684,574	UniSTS	RGSC3.4
Celera	2	167,971,950 - 167,972,162	UniSTS
RH 3.4 Map	2	1125.5	UniSTS
Cytogenetic Map	2	q34	UniSTS

AI007968

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	2	180,683,751 - 180,683,914	UniSTS	RGSC3.4
Celera	2	167,971,339 - 167,971,502	UniSTS
RH 3.4 Map	16	701.7	UniSTS
Cytogenetic Map	2	q34	UniSTS

AI007968

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	174,026,953 - 174,027,117 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	187,929,927 - 187,930,090	NCBI	Rnor6.0
Rnor_5.0	2	207,332,327 - 207,332,490	UniSTS	Rnor5.0
RGSC_v3.4	2	180,683,751 - 180,683,914	UniSTS	RGSC3.4
Celera	2	167,971,339 - 167,971,502	UniSTS
RH 3.4 Map	16	701.7	UniSTS
Cytogenetic Map	2	q34	UniSTS

Genetic Models

This gene Ubqln4 is modified in the following models/strains:

F344-Ubqln4^{Tn(sb-T2/Bart3)2.230Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026994 ⟹ ENSRNOP00000026994

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	176,310,579 - 176,325,924 (+)	Ensembl
mRatBN7.2 Ensembl	2	174,012,777 - 174,028,059 (+)	Ensembl
Rnor_6.0 Ensembl	2	187,915,751 - 187,931,035 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092752

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	176,310,568 - 176,325,723 (+)	Ensembl
mRatBN7.2 Ensembl	2	174,012,777 - 174,028,059 (+)	Ensembl
Rnor_6.0 Ensembl	2	187,915,752 - 187,924,872 (+)	Ensembl

RefSeq Acc Id:

NM_001107688 ⟹ NP_001101158

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	176,310,524 - 176,325,723 (+)	NCBI
mRatBN7.2	2	174,012,728 - 174,027,927 (+)	NCBI
Rnor_6.0	2	187,915,701 - 187,930,900 (+)	NCBI
Rnor_5.0	2	207,318,101 - 207,333,435 (+)	NCBI
RGSC_v3.4	2	180,669,525 - 180,684,724 (+)	RGD
Celera	2	167,957,113 - 167,972,312 (+)	RGD

Sequence:

show sequence

GTTGGAGGCTCCGGAGCCGAGCCGGGCCGGGCGGGCCAGGAGGAGGAGGAGGAGGAGGAGCTGG
GCGGGCTGGCGGGCGGCCGGGCGGCGGCATGGCGGAGCCGAGTGGGGCTGAGACGAGGCCCCAG
ATTCGGGTCACCGTCAAGACCCCCAAGGACAAGGAGGAGATCCTGATCTGCGATCAAGCCTCGG
TCAAGGAGTTCAAGGAGGAAATCTCCCGGAGGTTTAAGGCTCAGCAGGATCAGCTGGTCCTGAT
CTTCGCAGGCAAGATCCTCAAGGATGGAGACACACTGAACCAGCATGGGATCAAGGACGGGCTC
ACGGTTCATCTAGTCATCAAAACCCCTCAGAAGGCTCAAGATCCAGTGACTACTACTGCTTCCT
CCCCATCCACTCCTGACTCTGCCTCAGCACCCTCCACCACGCCTGCCTCACCTGCGGCCCCTGT
CCAGCCCTGCAGCTCTGGCAATACTACTTCAGATGCTAGCAGTGGAGGGGGGCCTTCTCCAGTG
GCGGCAGAGGGACCCTCAAATGCCACTGCATCAATTCTTTCTGGCTTTGGGGGCATCCTGGGCC
TGGGCAGCCTGGGCCTGGGCTCCGCCAACTTTATGGAGCTACAGCAACAGATGCAGCGGCAGCT
CATGTCCAATCCTGAGATGCTGTCGCAGATCATGGAGAACCCCCTGGTCCAGGATATGATGTCA
AACCCTGACCTGATGCGCCACATGATCATGGCTAACCCCCAGATGCAACAGCTGATGGAGAGGA
ACCCTGAGATCAGTCACATGCTCAACAACCCGGAGCTCATGAGGCAGACAATGGAGCTTGCTCG
TAACCCAGCCATGATGCAAGAAATGATGCGGAACCAGGACCGGGCCCTCAGCAACCTGGAAAGT
GTCCCGGGAGGGTATAATGCCCTCCGCCGCATGTACACGGACATCCAGGAACCCATGTTCACTG
CTGCCCGGGAACAGTTTGGCAACAATCCCTTCTCTTCCCTGGCCGGGAACTCCGACAACTCATC
CTCCCAACCTCTTCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCCCCTCGCCCCCC
ACCTCCCAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACC
CGACAGTCTCGAACCCCTTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCAACAGCCC
AGAAATGCAGGCGCTGCTCCAGCAGATTTCTGAAAACCCCCAGCTGATGCAGAATGTCATCTCG
GCCCCTTACATGCGCACCATGATGCAGACGCTTGCCCAGAACCCTGACTTTGCTGCTCAGATGA
TGGTGAATGTACCGCTGTTTGCAGGGAATCCACAACTCCAGGAGCAGCTGCGCCTGCAGCTCCC
TGTATTTCTGCAGCAGATGCAGAACCCAGAGTCTCTCTCCATCCTCACCAACCCACGGGCCATG
CAAGCCTTGCTGCAGATCCAGCAGGGGCTGCAGACCCTCCAGACTGAAGCCCCTGGGCTAGTAC
CCAGCCTTGGCTCCTTTGGGACACCCCGGACCTCGGTACCTTTGGCAGGCAGCAACTCTGGATC
TGCAGCCGAGGCCCCCACTGCTTCCCCAGGCACACCAGCCACAACTCCTCCCAGTGCGGGTTCC
AATACCCAGCAGCAACTCATGCAGCAGATGATCCAACTTTTGTCTGGAAGTGGGAACTCACAGG
TTCCAGTGCCAGAAGTGAGATTTCAACAGCAGCTGGAGCAGCTCAACTCCATGGGCTTTGTCAA
CCGTGAGGCCAACCTACAAGCCCTGATCGCCACAGGAGGGGACATCAATGCGGCTATTGAGAGA
CTCCTGGGATCCCAGCTCTCCTGACCCCTTGGCTTGTGCCTCTTTTGTTCCCCACCTCTCAGTG
CCAGCCTTTGGCTCCTGTCAAGCCCTACCTTCTATAGTCTGTCTTCTTTGATCCCTACGAAAAG
CAGGGTGACTGCCGAGGCCTGTGCCCAACCCATAGCTCTGTCCAAGGATTTTGATTTGTTGTTG
TCTCATGAAATCTCTCCTGGTCCTCTTGGAGCAGAGCTATCTAGTGTGCACAGTGTATCAGTTG
GCCACACCTCCTTGCCCGAAAGCACCTTGGCAGCGGGACTGAGAGGAGGACCCAGTCTGGCTAA
TCGGAAGTCTTCCATCGGTACCACTAGAGTTTAGCTTGCCTTACATGTACTCCTCTTCTCCTGC
CCTCACCTCAGCCCAACCGGTGTTTGAATTTCACTCTTTGGCCAGGCTCTGGTGACACTGTGGT
TTTCTCTCTCTACACCTATACTGATTCGACCAGCACTTTTTCATGGGCTCCTTTGTGACTCTGA
GGCAGGGAAAAAGATACCTATCCTTCTGTCCAAAGGGAGCAGTGAGTCAGCACTCTGGGCAGGA
TTATCAAGATCAAACAGGACCAGTGGGGCCCGGTGCTGAAGAGCAACACCTGAGAGTCCTTGGA
AGCAGGGACTCAGGGGACAGCCTGAGCGGGTTCAGAAGTCAGTCTAGAGACACCCACAGATTTC
ACGGTGGAGAAGGCAGGCTCAGGCCTGACGGAAGAAGAGAGACTAATGAACTGTGAACTGAAGA
GAGGAGCTCAACAAAACTGACCAGGAATCAGACTGGCTCCGCTGTTTCCAAATATCATGCCCTC
ACACACACTGCATGAGCCCAGCCTTCAGGCTCCACTCCAGACCCGATGGGGTTCTCAGCTCTGT
AGGACATCTGTATAAGTGAATACATGCAGGCTGGGGAGGTTGTTCCTCGTTGATTTGTGTTTCA
CAACTTTGTCAACAGAGGGAGCTGGGACCCTTGGTCTCCGGATCTGGGGTAACCAGAAAGCATA
TTGGGTAATTCTTCTAGTGGTTATGGCTCCAACTGGTACCCGGCCACCTCGGTGAAAGAATAGT
GAGGTTTCTCTCCCAGAGTTCCTGCCTTTCAGTTCCTCGCTGGTTCCCTTTAGGCCACAAAGTT
CTATTTGAGGAGAAGTAGAAAGGCAGATGCCTTTGGTATGGAATTGGGCTTTGCTCAACTAGAG
TACTGAGGAAGCCCTCACCACATTCTCTCTGCCCTACGGTCCAGGTACTTGGAGGACCCCTGGC
TGAGAGGCGGAGGTGAGAAAAGGCATCCTGCTTGGTCCCAAGCAGTTCAGACATGCCTTCCTCT
TCCCCTCCCAACACCCACCCTGGCCCTTGTAAATAAATAATGTGGTTTTTGTGAGATT

hide sequence

RefSeq Acc Id:

XM_006232642 ⟹ XP_006232704

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	176,310,589 - 176,325,724 (+)	NCBI
mRatBN7.2	2	174,012,726 - 174,028,062 (+)	NCBI
Rnor_6.0	2	187,915,740 - 187,931,035 (+)	NCBI
Rnor_5.0	2	207,318,101 - 207,333,435 (+)	NCBI

Sequence:

show sequence

GAGGAGGAGGAGGAGGAGGAGCTGGGCGGGCTGGCGGGCGGCCGGGCGGCGGCATGGCGGAGCC
GAGTGGGGCTGAGACGAGGCCCCAGATTCGGGTCACCGTCAAGACCCCCAAGGACAAGGAGGAG
ATCCTGATCTGCGATCAAGCCTCGGTCAAGGAGTTCAAGGAGGAAATCTCCCGGAGGTTTAAGG
CTCAGCAGGATCAGCTGGTCCTGATCTTCGCAGGCAAGATCCTCAAGGATGGAGACACACTGAA
CCAGCATGGGATCAAGGACGGGCTCACGGTTCATCTAGTCATCAAAACCCCTCAGAAGGCTCAA
GATCCAGTGACTACTACTGCTTCCTCCCCATCCACTCCTGACTCTGCCTCAGCACCCTCCACCA
CGCCTGCCTCACCTGCGGCCCCTGTCCAGCCCTGCAGCTCTGGCAATACTACTTCAGATGCTAG
CAGTGGAGGGGGGCCTTCTCCAGTGGCGGCAGAGGGACCCTCAAATGCCACTGCATCAATTCTT
TCTGGCTTTGGGGGCATCCTGGGCCTGGGCAGCCTGGGCCTGGGCTCCGCCAACTTTATGGAGC
TACAGCAACAGATGCAGCGGCAGCTCATGTCCAATCCTGAGATGCTGTCGCAGATCATGGAGAA
CCCCCTGGTCCAGGATATGATGTCAAACCCTGACCTGATGCGCCACATGATCATGGCTAACCCC
CAGATGCAACAGCTGATGGAGAGGAACCCTGAGATCAGTCACATGCTCAACAACCCGGAGCTCA
TGAGGCAGTTTGGCAACAATCCCTTCTCTTCCCTGGCCGGGAACTCCGACAACTCATCCTCCCA
ACCTCTTCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCCCCTCGCCCCCCACCTCC
CAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAG
TCTCGAACCCCTTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCAACAGCCCAGAAAT
GCAGGCGCTGCTCCAGCAGATTTCTGAAAACCCCCAGCTGATGCAGAATGTCATCTCGGCCCCT
TACATGCGCACCATGATGCAGACGCTTGCCCAGAACCCTGACTTTGCTGCTCAGATGATGGTGA
ATGTACCGCTGTTTGCAGGGAATCCACAACTCCAGGAGCAGCTGCGCCTGCAGCTCCCTGTATT
TCTGCAGCAGATGCAGAACCCAGAGTCTCTCTCCATCCTCACCAACCCACGGGCCATGCAAGCC
TTGCTGCAGATCCAGCAGGGGCTGCAGACCCTCCAGACTGAAGCCCCTGGGCTAGTACCCAGCC
TTGGCTCCTTTGGGACACCCCGGACCTCGGTACCTTTGGCAGGCAGCAACTCTGGATCTGCAGC
CGAGGCCCCCACTGCTTCCCCAGGCACACCAGCCACAACTCCTCCCAGTGCGGGTTCCAATACC
CAGCAGCAACTCATGCAGCAGATGATCCAACTTTTGTCTGGAAGTGGGAACTCACAGGTTCCAG
TGCCAGAAGTGAGATTTCAACAGCAGCTGGAGCAGCTCAACTCCATGGGCTTTGTCAACCGTGA
GGCCAACCTACAAGCCCTGATCGCCACAGGAGGGGACATCAATGCGGCTATTGAGAGACTCCTG
GGATCCCAGCTCTCCTGACCCCTTGGCTTGTGCCTCTTTTGTTCCCCACCTCTCAGTGCCAGCC
TTTGGCTCCTGTCAAGCCCTACCTTCTATAGTCTGTCTTCTTTGATCCCTACGAAAAGCAGGGT
GACTGCCGAGGCCTGTGCCCAACCCATAGCTCTGTCCAAGGATTTTGATTTGTTGTTGTCTCAT
GAAATCTCTCCTGGTCCTCTTGGAGCAGAGCTATCTAGTGTGCACAGTGTATCAGTTGGCCACA
CCTCCTTGCCCGAAAGCACCTTGGCAGCGGGACTGAGAGGAGGACCCAGTCTGGCTAATCGGAA
GTCTTCCATCGGTACCACTAGAGTTTAGCTTGCCTTACATGTACTCCTCTTCTCCTGCCCTCAC
CTCAGCCCAACCGGTGTTTGAATTTCACTCTTTGGCCAGGCTCTGGTGACACTGTGGTTTTCTC
TCTCTACACCTATACTGATTCGACCAGCACTTTTTCATGGGCTCCTTTGTGACTCTGAGGCAGG
GAAAAAGATACCTATCCTTCTGTCCAAAGGGAGCAGTGAGTCAGCACTCTGGGCAGGATTATCA
AGATCAAACAGGACCAGTGGGGCCCGGTGCTGAAGAGCAACACCTGAGAGTCCTTGGAAGCAGG
GACTCAGGGGACAGCCTGAGCGGGTTCAGAAGTCAGTCTAGAGACACCCACAGATTTCACGGTG
GAGAAGGCAGGCTCAGGCCTGACGGAAGAAGAGAGACTAATGAACTGTGAACTGAAGAGAGGAG
CTCAACAAAACTGACCAGGAATCAGACTGGCTCCGCTGTTTCCAAATATCATGCCCTCACACAC
ACTGCATGAGCCCAGCCTTCAGGCTCCACTCCAGACCCGATGGGGTTCTCAGCTCTGTAGGACA
TCTGTATAAGTGAATACATGCAGGCTGGGGAGGTTGTTCCTCGTTGATTTGTGTTTCACAACTT
TGTCAACAGAGGGAGCTGGGACCCTTGGTCTCCGGATCTGGGGTAACCAGAAAGCATATTGGGT
AATTCTTCTAGTGGTTATGGCTCCAACTGGTACCCGGCCACCTCGGTGAAAGAATAGTGAGGTT
TCTCTCCCAGAGTTCCTGCCTTTCAGTTCCTCGCTGGTTCCCTTTAGGCCACAAAGTTCTATTT
GAGGAGAAGTAGAAAGGCAGATGCCTTTGGTATGGAATTGGGCTTTGCTCAACTAGAGTACTGA
GGAAGCCCTCACCACATTCTCTCTGCCCTACGGTCCAGGTACTTGGAGGACCCCTGGCTGAGAG
GCGGAGGTGAGAAAAGGCATCCTGCTTGGTCCCAAGCAGTTCAGACATGCCTTCCTCTTCCCCT
CCCAACACCCACCCTGGCCCTTGTAAATAAATAATGTGGTTTTTGTGAGATTATATTGGTGTTT
GTTTTCTGAGGGAGGAATCATGCTGAAGACACACCACTGTCTGTCTGGAATTGGGCTTGGGTTT
GATGTTCTAAGAGGATGTCACTGAAATCCAAGCTTTAATAAAGAACAGAAGTAATAGAA

hide sequence

RefSeq Acc Id:

XM_039102310 ⟹ XP_038958238

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	176,313,413 - 176,325,724 (+)	NCBI
mRatBN7.2	2	174,015,607 - 174,028,062 (+)	NCBI

RefSeq Acc Id:

XM_039102311 ⟹ XP_038958239

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	176,316,357 - 176,325,724 (+)	NCBI
mRatBN7.2	2	174,018,486 - 174,028,062 (+)	NCBI

RefSeq Acc Id:

XM_063281838 ⟹ XP_063137908

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	176,310,585 - 176,325,724 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101158	(Get FASTA)	NCBI Sequence Viewer
	XP_006232704	(Get FASTA)	NCBI Sequence Viewer
	XP_038958238	(Get FASTA)	NCBI Sequence Viewer
	XP_038958239	(Get FASTA)	NCBI Sequence Viewer
	XP_063137908	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM00699	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026994
	ENSRNOP00000026994.4
	ENSRNOP00000086536
	ENSRNOP00000086536.1

RefSeq Acc Id:

NP_001101158 ⟸ NM_001107688

- UniProtKB:

D4A3P1 (UniProtKB/TrEMBL), A6J690 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEPSGAETRPQIRVTVKTPKDKEEILICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDG
DTLNQHGIKDGLTVHLVIKTPQKAQDPVTTTASSPSTPDSASAPSTTPASPAAPVQPCSSGNTT
SDASSGGGPSPVAAEGPSNATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQ
IMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNPAMMQEMM
RNQDRALSNLESVPGGYNALRRMYTDIQEPMFTAAREQFGNNPFSSLAGNSDNSSSQPLRTENR
EPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQI
SENPQLMQNVISAPYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNP
ESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGTPRTSVPLAGSNSGSAAEAPTASP
GTPATTPPSAGSNTQQQLMQQMIQLLSGSGNSQVPVPEVRFQQQLEQLNSMGFVNREANLQALI
ATGGDINAAIERLLGSQLS

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RefSeq Acc Id:	XP_006232704 ⟸ XM_006232642
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A1E6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEPSGAETRPQIRVTVKTPKDKEEILICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDG DTLNQHGIKDGLTVHLVIKTPQKAQDPVTTTASSPSTPDSASAPSTTPASPAAPVQPCSSGNTT SDASSGGGPSPVAAEGPSNATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQ IMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQFGNNPFSSLAGNSDN SSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFN SPEMQALLQQISENPQLMQNVISAPYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQ LPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGTPRTSVPLAGSNS GSAAEAPTASPGTPATTPPSAGSNTQQQLMQQMIQLLSGSGNSQVPVPEVRFQQQLEQLNSMGF VNREANLQALIATGGDINAAIERLLGSQLS hide sequence

Ensembl Acc Id:

ENSRNOP00000026994 ⟸ ENSRNOT00000026994

RefSeq Acc Id:	XP_038958238 ⟸ XM_039102310
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038958239 ⟸ XM_039102311
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063137908 ⟸ XM_063281838
- Peptide Label:	isoform X2

Protein Domains

UBA Ubiquitin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A3P1-F1-model_v2	AlphaFold	D4A3P1	1-595	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691448

Promoter ID:

EPDNEW_R1971

Type:

multiple initiation site

Name:

Ubqln4_1

Description:

ubiquilin 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	187,915,763 - 187,915,823	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308273	AgrOrtholog
BioCyc Gene	G2FUF-52475	BioCyc
Ensembl Genes	ENSRNOG00000019933	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026994	ENTREZGENE
	ENSRNOT00000026994.8	UniProtKB/TrEMBL
	ENSRNOT00000092752	ENTREZGENE
	ENSRNOT00000092752.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.260.100	UniProtKB/TrEMBL
	DNA helicase RuvA subunit, C-terminal domain	UniProtKB/TrEMBL
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
InterPro	STI1_HS-bd	UniProtKB/TrEMBL
	UBA-like	UniProtKB/TrEMBL
	UBA/transl_elong_EF1B_N_euk	UniProtKB/TrEMBL
	Ubiquilin	UniProtKB/TrEMBL
	Ubiquitin	UniProtKB/TrEMBL
	Ubiquitin-rel_dom	UniProtKB/TrEMBL
KEGG Report	rno:310633	UniProtKB/TrEMBL
NCBI Gene	310633	ENTREZGENE
PANTHER	UBIQUILIN	UniProtKB/TrEMBL
	UBIQUILIN-4	UniProtKB/TrEMBL
Pfam	UBA	UniProtKB/TrEMBL
	ubiquitin	UniProtKB/TrEMBL
	UBQLN1	UniProtKB/TrEMBL
PhenoGen	Ubqln4	PhenoGen
PROSITE	UBA	UniProtKB/TrEMBL
	UBIQUITIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000019933	RatGTEx
SMART	STI1	UniProtKB/TrEMBL
	UBA	UniProtKB/TrEMBL
	UBQ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54236	UniProtKB/TrEMBL
	UBA_like	UniProtKB/TrEMBL
UniProt	A0A8I6A1E6	ENTREZGENE, UniProtKB/TrEMBL
	A6J690	ENTREZGENE, UniProtKB/TrEMBL
	D4A3P1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Ubqln4	ubiquilin 4	Ubqln4_predicted	ubiquilin 4 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Ubqln4_predicted	ubiquilin 4 (predicted)	RGD1308273_predicted	similar to UBIN (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1308273_predicted	similar to UBIN (predicted)	LOC310633_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC310633_predicted	similar to UBIN (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)