Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hvcn1 (hydrogen voltage-gated channel 1) Rattus norvegicus
Symbol: Hvcn1
Name: hydrogen voltage-gated channel 1
Description: Predicted to have identical protein binding activity and voltage-gated proton channel activity. Involved in positive regulation of superoxide anion generation and regulation of intracellular pH. Localizes to apical plasma membrane. Used to study middle cerebral artery infarction. Orthologous to human HVCN1 (hydrogen voltage gated channel 1); INTERACTS WITH amphetamine; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC304485; RGD1310788; similar to RIKEN cDNA 0610039P13; voltage-gated hydrogen channel 1
Homo sapiens (human) : HVCN1 (hydrogen voltage gated channel 1)  HGNC  Alliance
Mus musculus (house mouse) : Hvcn1 (hydrogen voltage-gated channel 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hvcn1 (hydrogen voltage gated channel 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HVCN1 (hydrogen voltage gated channel 1)
Canis lupus familiaris (dog) : HVCN1 (hydrogen voltage gated channel 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hvcn1 (hydrogen voltage gated channel 1)
Sus scrofa (pig) : HVCN1 (hydrogen voltage gated channel 1)
Chlorocebus sabaeus (African green monkey) : HVCN1 (hydrogen voltage gated channel 1)
Heterocephalus glaber (naked mole-rat) : Hvcn1 (hydrogen voltage gated channel 1)
more info ...
Allele / Splice: Hvcn1em1Mcwi   Hvcn1em2Mcwi  
Genetic Models: SS-Hvcn1em2Mcwi-/- SS-Hvcn1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01239,822,814 - 39,851,093 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,822,637 - 39,850,567 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,702,567 - 41,731,349 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,536,954 - 35,556,666 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,401,133 - 35,431,692 (-)NCBI
Celera1236,012,998 - 36,041,213 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Hvcn1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310788
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.