Rf41 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Rf41 (Renal function QTL 41) Rattus norvegicus

Symbol: Rf41
Name: Renal function QTL 41
RGD ID: 1331787
Previously known as: Specialized Center of Research QTL 11,13; SCOR11; SCOR13
Trait: kidney blood vessel physiology trait   (VT:0100012)    
Measurement Type: absolute change in renal blood flow rate   (CMO:0001168)    
LOD Score: 2.998
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8121 - 33,700,556RGD_MAPPER_PIPELINE
mRatBN7.21228,064,557 - 40,218,380RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01231,723,688 - 45,946,802RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01233,647,522 - 47,758,580RGDRnor5.0
RGSC_v3.41229,130,304 - 41,447,755RGDRGSC3.4
RGSC_v3.11228,993,692 - 41,311,143RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41Rathypertension  IAGP 70849 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41Ratabnormal renal plasma flow rate  IAGP 70849 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41Ratabsolute change in renal blood flow rate  IDA 70849 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41Ratangiotensin II  IDA 70849 RGD 
Rf41Ratcontrolled sodium content diet  IDA 70849 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41Ratelectromagnetic flowmetry  IDA 70849 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41RatBN/SsNHsd  IEA 70849 RGD 
Rf41RatSS/JrHsdMcwi  IEA 70849 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf41Ratkidney blood vessel physiology trait  IDA 70849 RGD 


#
Reference Title
Reference Citation
1. A genomic-systems biology map for cardiovascular function. Stoll M, etal., Science 2001 Nov 23;294(5547):1723-6.

Related QTL Description Reference
Bp218 maps to same region RGD:70849
Kidm11 maps to same region RGD:70849
Hrtrt14 maps to same region RGD:70849
Bp219 maps to same region RGD:70849



1 to 20 of 242 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1583825Fzd10frizzled class receptor 10122809837128101566Rat
11406627Rps20-ps3ribosomal protein S20, pseudogene 3122814558828146353Rat
41145714LOC120095942uncharacterized LOC120095942122824438928263727Rat
735062Tmem132dtransmembrane protein 132D122827003928917324Rat
40950631LOC120095943uncharacterized LOC120095943122830924128329042Rat
1304896Glt1d1glycosyltransferase 1 domain containing 1122897598429049707Rat
708469Slc15a4solute carrier family 15 member 4122904863429082480Rat
1583824Tmem132ctransmembrane protein 132C122911521329437900Rat
11472079LOC108352443uncharacterized LOC108352443122914059329146192Rat
41181629Tmem254-ps1transmembrane protein 254, pseudogene 1122939753429414987Rat
41348602LOC120095946uncharacterized LOC120095946122946757229469165Rat
41154964LOC120096083U2 spliceosomal RNA122946950029469687Rat
1559821Myl6l2myosin light chain 6 like 2122948809129488746Rat
41083776LOC120095947uncharacterized LOC120095947122950898329528608Rat
9386528Rpl7-ps7ribosomal protein L7, pseudogene 7122955463029556108Rat
9188281LOC103691337uncharacterized LOC103691337122964621429652464Rat
41351787LOC120095949uncharacterized LOC120095949122973060929736279Rat
41235196LOC120095951uncharacterized LOC120095951122986393629869460Rat
41366922LOC120095952uncharacterized LOC120095952122988752429899402Rat
11363226LOC108352445uncharacterized LOC108352445122995068830009315Rat

1 to 20 of 242 rows
1 to 20 of 353 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10125DXMgh7230123381916733819400Ratregion
10990D12Mco2242123871454038714782Ratregion
33955D1Mit22124123140994231410080Ratregion
33963D12Mit4198123819280938193007Ratregion
34070D12Mgh7138123569808835698226Ratregion
34086D12Mgh9135124021838040218516Ratregion
34389D12Mgh10132123769148537691617Ratregion
34729D12Mgh5124122806443328064557Ratregion
11281D12Wox15157123609153336091690Ratregion
11282D12Arb7340123609137936091727Ratregion
36101D12Rat15167122830212328302290Ratregion
36119D12Rat94267122905763229057901Ratregion
36125D12Rat14163122862266528622828Ratregion
37334D12Rat46158123039512130395279Ratregion
37366D12Rat54115123579702135797136Ratregion
35433D12Rat17153123082724630827399Ratregion
36818D12Rat25140123921527439215414Ratregion
37830D12Rat36206123210317432103380Ratregion
37874D12Rat31235123907476839075003Ratregion
36490D12Rat18161123470242634702587Ratregion
1 to 20 of 353 rows

Flank 1: (D12Mgh9)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21240,218,380 - 40,218,516 (+)MAPPER
Rnor_6.01245,946,802 - 45,946,937NCBI
Rnor_5.01247,758,580 - 47,758,715UniSTS
RGSC_v3.41241,447,755 - 41,447,890RGD
RGSC_v3.41241,447,755 - 41,447,890UniSTS
RGSC_v3.11241,311,143 - 41,311,278RGD
Celera1241,855,271 - 41,855,406UniSTS
Cytogenetic Map12 RGD
Peak: (D12Mgh9)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21240,218,380 - 40,218,516 (+)MAPPER
Rnor_6.01245,946,802 - 45,946,937NCBI
Rnor_5.01247,758,580 - 47,758,715UniSTS
RGSC_v3.41241,447,755 - 41,447,890RGD
RGSC_v3.41241,447,755 - 41,447,890UniSTS
RGSC_v3.11241,311,143 - 41,311,278RGD
Celera1241,855,271 - 41,855,406UniSTS
Cytogenetic Map12 RGD
Flank 2: (D12Mgh5)
Rat AssemblyChrPosition (strand)Source
GRCr81233,700,432 - 33,700,556 (+)Marker Load Pipeline
mRatBN7.21228,064,433 - 28,064,557 (+)MAPPER
Rnor_6.01231,723,565 - 31,723,688NCBI
Rnor_5.01233,647,399 - 33,647,522UniSTS
RGSC_v3.41229,130,181 - 29,130,304UniSTS
RGSC_v3.41229,130,180 - 29,130,304RGD
RGSC_v3.11228,993,569 - 28,993,692RGD
Celera1229,756,877 - 29,756,993UniSTS
RH 3.4 Map12466.8UniSTS
RH 3.4 Map12466.8RGD
RH 2.0 Map12343.2RGD
SHRSP x BN Map1231.95RGD
Cytogenetic Map12 RGD


1 to 10 of 59 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat

1 to 10 of 59 rows


Database
Acc Id
Source(s)
NCBI Gene Rf41

Note Type Note Reference
qtl_general suggestive linkage also found at this locus to change in renal blood flow from angiotensin II dose 3 minus control (SCOR13,LOD=2.5) 70849
qtl_general change in renal blood flow from angiotensin II dose 2 minus control (SCOR11) 70849
qtl_general additional information, including phenotype and mapping information, can be found at A genomics-systems biology map for cardiovascular function 70849