Slc8b1 (solute carrier family 8 member B1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Slc8b1 (solute carrier family 8 member B1) Rattus norvegicus
Analyze
Symbol: Slc8b1
Name: solute carrier family 8 member B1
RGD ID: 1565818
Description: Enables protein homodimerization activity. Predicted to be involved in several processes, including calcium export from the mitochondrion; cellular calcium ion homeostasis; and regulation of insulin secretion. Predicted to act upstream of or within calcium ion transmembrane transport and sodium ion transmembrane transport. Located in mitochondrial crista and sarcolemma. Orthologous to human SLC8B1 (solute carrier family 8 member B1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC498185; na(+)/K(+)/Ca(2+)-exchange protein 6; similar to sodium/calcium exchanger protein; Slc24a6; sodium/calcium exchanger protein, mitochondrial; sodium/potassium/calcium exchanger 6; sodium/potassium/calcium exchanger 6, mitochondrial; solute carrier family 24 (sodium/lithium/calcium exchanger), member 6; solute carrier family 24 (sodium/potassium/calcium exchanger), member 6; solute carrier family 24 member 6; solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21236,029,759 - 36,053,087 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,029,760 - 36,053,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1237,208,956 - 37,232,225 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01237,820,175 - 37,843,444 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01236,872,639 - 36,895,908 (-)NCBIRnor_WKY
Rnor_6.01241,566,980 - 41,590,294 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,566,981 - 41,590,244 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01243,421,506 - 43,444,143 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,227,844 - 37,250,698 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1237,689,943 - 37,713,214 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6. Cai X and Lytton J, J Biol Chem. 2004 Feb 13;279(7):5867-76. Epub 2003 Nov 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Palty R, etal., Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):436-41. doi: 10.1073/pnas.0908099107. Epub 2009 Dec 15.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Mitochondria as sensors and regulators of calcium signalling. Rizzuto R, etal., Nat Rev Mol Cell Biol. 2012 Sep;13(9):566-78. doi: 10.1038/nrm3412. Epub 2012 Aug 1.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Alteration of intracellular calcium and its modulator SLC24A6 after experimental intracerebral hemorrhage. Zheng M, etal., Acta Neurochir Suppl. 2013;118:169-73. doi: 10.1007/978-3-7091-1434-6_31.
Additional References at PubMed
PMID:15060069   PMID:15489334   PMID:23056385   PMID:24067497   PMID:24898248   PMID:27328625   PMID:28219928   PMID:28445457   PMID:29223733  


Genomics

Comparative Map Data
Slc8b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21236,029,759 - 36,053,087 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,029,760 - 36,053,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1237,208,956 - 37,232,225 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01237,820,175 - 37,843,444 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01236,872,639 - 36,895,908 (-)NCBIRnor_WKY
Rnor_6.01241,566,980 - 41,590,294 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,566,981 - 41,590,244 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01243,421,506 - 43,444,143 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,227,844 - 37,250,698 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1237,689,943 - 37,713,214 (-)NCBICelera
Cytogenetic Map12q16NCBI
SLC8B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812113,298,771 - 113,335,109 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12113,298,759 - 113,359,493 (-)EnsemblGRCh38hg38GRCh38
GRCh3712113,736,576 - 113,772,914 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612112,220,954 - 112,257,308 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412112,199,291 - 112,235,645NCBI
Celera12113,363,396 - 113,399,748 (-)NCBICelera
Cytogenetic Map12q24.13NCBI
HuRef12110,749,040 - 110,785,386 (-)NCBIHuRef
CHM1_112113,704,819 - 113,741,134 (-)NCBICHM1_1
T2T-CHM13v2.012113,275,399 - 113,311,727 (-)NCBIT2T-CHM13v2.0
Slc8b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395120,649,233 - 120,672,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5120,649,233 - 120,672,089 (+)EnsemblGRCm39 Ensembl
GRCm385120,511,168 - 120,534,024 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5120,511,168 - 120,534,024 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,961,201 - 120,984,033 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365120,771,809 - 120,794,636 (+)NCBIMGSCv36mm8
Celera5117,595,553 - 117,618,613 (+)NCBICelera
Cytogenetic Map5FNCBI
Slc8b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554829,595,604 - 9,605,271 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554829,594,872 - 9,617,136 (-)NCBIChiLan1.0ChiLan1.0
SLC8B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112114,286,624 - 114,319,683 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12114,286,624 - 114,319,683 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012110,903,215 - 110,936,908 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC8B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12610,662,491 - 10,688,182 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2610,662,208 - 10,687,629 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2610,784,902 - 10,810,095 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02610,906,960 - 10,932,125 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2610,906,963 - 10,932,067 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12610,880,877 - 10,906,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02610,943,518 - 10,968,703 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02610,992,669 - 11,017,851 (-)NCBIUU_Cfam_GSD_1.0
Slc8b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118148,663,425 - 148,682,942 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366683,160,148 - 3,181,814 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC8B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1438,773,407 - 38,808,265 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11438,773,396 - 38,808,261 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,272,619 - 41,288,609 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC8B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111108,553,545 - 108,590,017 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11108,553,794 - 108,589,533 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037136,502,914 - 136,538,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc8b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474719,168,834 - 19,178,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474719,158,395 - 19,179,450 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc8b1
238 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:349
Count of miRNA genes:200
Interacting mature miRNAs:241
Transcripts:ENSRNOT00000038736
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)122806443340130419Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)122806455740218380Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)122860752637691617Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

Markers in Region
RH130280  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21236,029,809 - 36,029,992 (+)MAPPERmRatBN7.2
Rnor_6.01241,567,031 - 41,567,213NCBIRnor6.0
Rnor_5.01243,421,557 - 43,421,739UniSTSRnor5.0
RGSC_v3.41237,227,895 - 37,228,077UniSTSRGSC3.4
Celera1237,689,994 - 37,690,176UniSTS
RH 3.4 Map12646.1UniSTS
Cytogenetic Map12q16UniSTS
RH131571  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21236,029,358 - 36,029,551 (+)MAPPERmRatBN7.2
Rnor_6.01241,566,580 - 41,566,772NCBIRnor6.0
Rnor_5.01243,421,106 - 43,421,298UniSTSRnor5.0
RGSC_v3.41237,227,444 - 37,227,636UniSTSRGSC3.4
Celera1237,689,543 - 37,689,735UniSTS
RH 3.4 Map12646.8UniSTS
Cytogenetic Map12q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 24 19 16 19 24 25 11
Low 43 33 22 3 22 8 11 74 11 16 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000038736   ⟹   ENSRNOP00000034026
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,029,760 - 36,053,031 (-)Ensembl
Rnor_6.0 Ensembl1241,566,981 - 41,590,244 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094097   ⟹   ENSRNOP00000096132
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,030,539 - 36,053,031 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094252   ⟹   ENSRNOP00000095205
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,030,539 - 36,053,031 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095087   ⟹   ENSRNOP00000096275
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,030,489 - 36,053,031 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095422   ⟹   ENSRNOP00000086798
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,030,539 - 36,053,031 (-)Ensembl
RefSeq Acc Id: NM_001017488   ⟹   NP_001017488
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,029,759 - 36,053,031 (-)NCBI
Rnor_6.01241,566,980 - 41,590,244 (-)NCBI
Rnor_5.01243,421,506 - 43,444,143 (-)NCBI
RGSC_v3.41237,227,844 - 37,250,698 (-)RGD
Celera1237,689,943 - 37,713,214 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089705   ⟹   XP_038945633
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,029,759 - 36,053,087 (-)NCBI
RefSeq Acc Id: XR_005491667
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,029,759 - 36,053,087 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001017488 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945633 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79350 (Get FASTA)   NCBI Sequence Viewer  
  EDM13779 (Get FASTA)   NCBI Sequence Viewer  
  Q6AXS0 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001017488   ⟸   NM_001017488
- Peptide Label: precursor
- UniProtKB: Q6AXS0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000034026   ⟸   ENSRNOT00000038736
RefSeq Acc Id: XP_038945633   ⟸   XM_039089705
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000095205   ⟸   ENSRNOT00000094252
RefSeq Acc Id: ENSRNOP00000086798   ⟸   ENSRNOT00000095422
RefSeq Acc Id: ENSRNOP00000096275   ⟸   ENSRNOT00000095087
RefSeq Acc Id: ENSRNOP00000096132   ⟸   ENSRNOT00000094097
Protein Domains
Na_Ca_ex

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXS0-F1-model_v2 AlphaFold Q6AXS0 1-585 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698665
Promoter ID:EPDNEW_R9190
Type:initiation region
Name:Slc8b1_1
Description:solute carrier family 8 member B1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01241,590,241 - 41,590,301EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565818 AgrOrtholog
BioCyc Gene G2FUF-19173 BioCyc
Ensembl Genes ENSRNOG00000001383 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000034026 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000086798.1 UniProtKB/TrEMBL
  ENSRNOP00000095205.1 UniProtKB/TrEMBL
  ENSRNOP00000096132.1 UniProtKB/TrEMBL
  ENSRNOP00000096275.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038736 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000094097.1 UniProtKB/TrEMBL
  ENSRNOT00000094252.1 UniProtKB/TrEMBL
  ENSRNOT00000095087.1 UniProtKB/TrEMBL
  ENSRNOT00000095422.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1420.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107820 IMAGE-MGC_LOAD
InterPro NaCa_Exmemb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NCX_ion-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:498185 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94807 IMAGE-MGC_LOAD
NCBI Gene 498185 ENTREZGENE
Pfam Na_Ca_ex UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc8b1 PhenoGen
UniProt A0A8I6A2Y3_RAT UniProtKB/TrEMBL
  A0A8I6APW6_RAT UniProtKB/TrEMBL
  A0A8I6AQA3_RAT UniProtKB/TrEMBL
  A0A8I6AUV1_RAT UniProtKB/TrEMBL
  NCLX_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc8b1  solute carrier family 8 member B1  Slc8b1  solute carrier family 8 (sodium/lithium/calcium exchanger), member B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-12 Slc8b1  solute carrier family 8 (sodium/lithium/calcium exchanger), member B1  Slc24a6  solute carrier family 24 (sodium/lithium/calcium exchanger), member 6  Name and Symbol changed 629549 APPROVED
2012-10-16 Slc24a6  solute carrier family 24 (sodium/lithium/calcium exchanger), member 6  Slc24a6  solute carrier family 24 (sodium/potassium/calcium exchanger), member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Slc24a6  solute carrier family 24 (sodium/potassium/calcium exchanger), member 6  LOC498185  similar to sodium/calcium exchanger protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498185  similar to sodium/calcium exchanger protein      Symbol and Name status set to provisional 70820 PROVISIONAL