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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | RGD:734054 | 6480464 | ethylene dichloride results in decreased expression of SDS mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:734054 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of SDS mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of SDS mRNA | CTD | PMID:25380136 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:734054 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SDS mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:20056577 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:734054 | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of SDS mRNA more ... | CTD | PMID:16214954 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:734054 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SDS mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:734053 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SDS mRNA | CTD | PMID:20106945, PMID:26159488 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:734053 | 6480464 | Endosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SDS mRNA], Tetrachlorodibenzodioxin inhibits the reaction [Endosulfan results in increased expression of SDS mRNA] | CTD | PMID:26159488 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SDS mRNA | CTD | PMID:20959002, PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:734053 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SDS mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:734054 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SDS mRNA | CTD | PMID:18172886 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SDS mRNA | CTD | PMID:16054898, PMID:32109520 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of SDS mRNA | CTD | PMID:21346803 | 2-nitrofluorene | decreases expression | EXP | | 6480464 | 2-nitrofluorene results in decreased expression of SDS mRNA | CTD | PMID:14600272 | 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | RGD:734053 | 6480464 | 3 more ... | CTD | PMID:21703328 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:27509375, PMID:29474705 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of SDS mRNA | CTD | PMID:25380136 | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | decreases expression | EXP | | 6480464 | 4-N-methyl-N-nitrosamino-1-3-pyridyl-1-butanone results in decreased expression of SDS mRNA | CTD | PMID:14600272 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SDS mRNA | CTD | PMID:24780913, PMID:25825206 | acetylsalicylic acid | increases expression | ISO | RGD:734053 | 6480464 | Aspirin results in increased expression of SDS mRNA | CTD | PMID:11906190 | aflatoxin B1 | affects expression | ISO | RGD:734053 | 6480464 | Aflatoxin B1 affects the expression of SDS protein | CTD | PMID:20106945 | aflatoxin B1 | decreases expression | ISO | RGD:734053 | 6480464 | Aflatoxin B1 results in decreased expression of SDS mRNA | CTD | PMID:32234424 | aflatoxin B1 | increases methylation | ISO | RGD:734053 | 6480464 | Aflatoxin B1 results in increased methylation of SDS intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | RGD:734053 | 6480464 | Tretinoin results in increased expression of SDS mRNA | CTD | PMID:16054129 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SDS mRNA | CTD | PMID:16483693 | benzene | increases expression | ISO | RGD:734053 | 6480464 | Benzene results in increased expression of SDS mRNA | CTD | PMID:19162166 | benzo[a]pyrene | decreases expression | ISO | RGD:734053 | 6480464 | Benzoapyrene results in decreased expression of SDS mRNA | CTD | PMID:20106945, PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | RGD:734053 | 6480464 | Benzoapyrene results in decreased methylation of SDS 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:734054 | 6480464 | Benzoapyrene results in decreased expression of SDS mRNA | CTD | PMID:19770486, PMID:22228805 | beta-naphthoflavone | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SDS mRNA | CTD | PMID:18164116 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:734054 | 6480464 | Diethylhexyl Phthalate results in increased expression of SDS mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:734054 | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SDS mRNA] | CTD | PMID:19850644 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SDS mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SDS mRNA | CTD | PMID:30816183 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SDS mRNA | CTD | PMID:30903817 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of SDS mRNA | CTD | PMID:32479839 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of SDS mRNA | CTD | PMID:24136188 | calcitriol | decreases expression | ISO | RGD:734053 | 6480464 | Calcitriol results in decreased expression of SDS mRNA | CTD | PMID:26485663 | ciguatoxin CTX1B | affects expression | ISO | RGD:734054 | 6480464 | Ciguatoxins affects the expression of SDS mRNA | CTD | PMID:18353800 | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of SDS mRNA | CTD | PMID:22465980 | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of SDS mRNA | CTD | PMID:22465980 | cyclosporin A | decreases expression | ISO | RGD:734053 | 6480464 | Cyclosporine results in decreased expression of SDS mRNA | CTD | PMID:20106945 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of SDS mRNA | CTD | PMID:23640034 | diethyl maleate | decreases expression | EXP | | 6480464 | diethyl maleate results in decreased expression of SDS mRNA | CTD | PMID:21161181 | endosulfan | increases expression | ISO | RGD:734053 | 6480464 | Endosulfan results in increased expression of SDS mRNA | CTD | PMID:26159488 | endosulfan | multiple interactions | ISO | RGD:734053 | 6480464 | Endosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SDS mRNA], Tetrachlorodibenzodioxin inhibits the reaction [Endosulfan results in increased expression of SDS mRNA] | CTD | PMID:26159488 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of SDS mRNA | CTD | PMID:15353170 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of SDS mRNA | CTD | PMID:16946407 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of SDS mRNA | CTD | PMID:24136188 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of SDS mRNA | CTD | PMID:24136188 | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of SDS mRNA | CTD | PMID:31324951 | methotrexate | increases expression | ISO | RGD:734053 | 6480464 | Methotrexate results in increased expression of SDS mRNA | CTD | PMID:17400583 | monosodium L-glutamate | increases expression | ISO | RGD:734054 | 6480464 | Sodium Glutamate results in increased expression of SDS mRNA | CTD | PMID:22078008 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SDS mRNA, [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SDS mRNA | CTD | PMID:18164116, PMID:20360939 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:734054 | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SDS mRNA | CTD | PMID:24535843 | N-nitrosodimethylamine | decreases expression | EXP | | 6480464 | Dimethylnitrosamine results in decreased expression of SDS mRNA | CTD | PMID:14600272, PMID:25380136 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of SDS mRNA | CTD | PMID:24136188 | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of SDS mRNA | CTD | PMID:24136188 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of SDS mRNA | CTD | PMID:25838073 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SDS mRNA | CTD | PMID:17202762, PMID:30723492 | paracetamol | decreases expression | ISO | RGD:734053 | 6480464 | Acetaminophen results in decreased expression of SDS mRNA | CTD | PMID:29067470 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SDS mRNA | CTD | PMID:17366322 | paracetamol | affects expression | ISO | RGD:734054 | 6480464 | Acetaminophen affects the expression of SDS mRNA | CTD | PMID:17562736 | pentachlorophenol | increases expression | ISO | RGD:734054 | 6480464 | Pentachlorophenol results in increased expression of SDS mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | affects expression | ISO | RGD:734054 | 6480464 | perfluorooctane sulfonic acid affects the expression of SDS mRNA | CTD | PMID:19429403 | perfluorooctanoic acid | affects expression | ISO | RGD:734054 | 6480464 | perfluorooctanoic acid affects the expression of SDS mRNA | CTD | PMID:19429403 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of SDS mRNA | CTD | PMID:19162173 | phenethyl caffeate | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SDS mRNA | CTD | PMID:20360939 | phenformin | increases expression | EXP | | 6480464 | Phenformin results in increased expression of SDS mRNA | CTD | PMID:31324951 | phenobarbital | multiple interactions | ISO | RGD:734054 | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SDS mRNA, NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SDS mRNA] | CTD | PMID:19482888, PMID:24535843 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of SDS mRNA | CTD | PMID:19162173 | phenobarbital | increases expression | ISO | RGD:734054 | 6480464 | Phenobarbital results in increased expression of SDS mRNA | CTD | PMID:19270015 | phenobarbital | decreases expression | ISO | RGD:734054 | 6480464 | Phenobarbital results in decreased expression of SDS mRNA | CTD | PMID:19482888 | phlorizin | decreases expression | ISO | RGD:734054 | 6480464 | Phlorhizin results in decreased expression of SDS mRNA | CTD | PMID:22538082 | piperonyl butoxide | decreases expression | EXP | | 6480464 | Piperonyl Butoxide results in decreased expression of SDS mRNA | CTD | PMID:22484513 | pirinixic acid | increases expression | ISO | RGD:734054 | 6480464 | pirinixic acid results in increased expression of SDS mRNA | CTD | PMID:18445702 | pirinixic acid | multiple interactions | ISO | RGD:734054 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SDS mRNA | CTD | PMID:19710929 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of SDS mRNA | CTD | PMID:19162173 | propiconazole | decreases expression | ISO | RGD:734054 | 6480464 | propiconazole results in decreased expression of SDS mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | EXP | | 6480464 | [resveratrol co-treated with Streptozocin] results in decreased expression of SDS mRNA | CTD | PMID:25905778 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SDS mRNA | CTD | PMID:28374803 | streptozocin | multiple interactions | EXP | | 6480464 | [resveratrol co-treated with Streptozocin] results in decreased expression of SDS mRNA | CTD | PMID:25905778 | tamoxifen | affects expression | ISO | RGD:734054 | 6480464 | Tamoxifen affects the expression of SDS mRNA | CTD | PMID:20937368 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SDS protein | CTD | PMID:12629582 | tetrachloromethane | decreases expression | ISO | RGD:734054 | 6480464 | Carbon Tetrachloride results in decreased expression of SDS mRNA | CTD | PMID:27339419, PMID:31919559 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of SDS mRNA | CTD | PMID:12734012 | theophylline | increases expression | ISO | RGD:734053 | 6480464 | Theophylline results in increased expression of SDS mRNA | CTD | PMID:16083514 | thioacetamide | multiple interactions | EXP | | 6480464 | Thioacetamide results in decreased expression of and results in decreased activity of SDS protein | CTD | PMID:15724435 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SDS mRNA | CTD | PMID:15724435, PMID:23411599 | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of SDS mRNA | CTD | PMID:30589522 | trovafloxacin | increases expression | EXP | | 6480464 | trovafloxacin results in increased expression of SDS mRNA | CTD | PMID:24136188 | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of SDS mRNA | CTD | PMID:24136188 | valproic acid | affects expression | ISO | RGD:734054 | 6480464 | Valproic Acid affects the expression of SDS mRNA | CTD | PMID:17292431, PMID:17963808 | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of SDS mRNA | CTD | PMID:12672911 | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of SDS mRNA | CTD | PMID:12672911 | |