Gene: Dtx1 (deltex E3 ubiquitin ligase 1) Rattus norvegicus
Symbol: Dtx1
Name: deltex E3 ubiquitin ligase 1
Description: Predicted to have Notch binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including cellular response to leukemia inhibitory factor; negative regulation of cell differentiation; and regulation of Notch signaling pathway. Predicted to localize to the cytosol and nuclear body. Orthologous to human DTX1 (deltex E3 ubiquitin ligase 1); INTERACTS WITH manganese(II) chloride; N-methyl-4-phenylpyridinium; 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: deltex 1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; deltex homolog 1 (Drosophila); E3 ubiquitin-protein ligase DTX1; LOC687424; similar to Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1)
Homo sapiens (human) : DTX1 (deltex E3 ubiquitin ligase 1)  HGNC  Alliance
Mus musculus (house mouse) : Dtx1 (deltex 1, E3 ubiquitin ligase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dtx1 (deltex E3 ubiquitin ligase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DTX1 (deltex E3 ubiquitin ligase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dtx1 (deltex E3 ubiquitin ligase 1)
Sus scrofa (pig) : DTX1 (deltex E3 ubiquitin ligase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01241,383,885 - 41,415,783 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01243,243,009 - 43,274,204 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1237,511,093 - 37,542,318 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dtx1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585380
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.